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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:1957.3 nTPM
HPA Brain:290.0 nTPM
GTEx:1957.3 nTPM
FANTOM5:29.8 Scaled Tags Per Million
Pig:559.6 nTPM
Mouse:624.6 nTPM
Allen mouse:4.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

290.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 258.7
2411 Female, age 72, unknown 308.7
1827 Male, age 72, unknown 303.4
2666 Male, age 74, left hemisphere 292.6
2828 Female, age 72, unknown 287.4
1870 Female, age 42, unknown 266.3
2019 Male, age 18, unknown 249.5
1833 Male, age 53, unknown 226.6
1830 Male, age 51, unknown 225.2
2586 Male, age 75, left hemisphere 217.2
2219 Male, age 76, both hemispheres 209.8
Dorsal raphe nucleus
nTPM: 255.4
2298 Female, age 72, unknown 320.0
2750 Male, age 76, both hemispheres 270.5
2016 Female, age 72, unknown 244.3
1828 Male, age 53, unknown 237.0
2047 Male, age 72, unknown 205.0
Inferior colliculus
nTPM: 248.5
2097 Female, age 72, unknown 299.0
1890 Male, age 53, unknown 265.5
1848 Female, age 42, unknown 219.9
2849 Male, age 72, unknown 209.4
Median raphe nucleus
nTPM: 243.7
2220 Male, age 76, midline 243.7
Periaquaductal grey, anterior
nTPM: 273.9
2502 Female, age 75, unknown 331.3
1947 Male, age 18, unknown 251.5
1795 Male, age 51, unknown 238.9
Periaquaductal grey, dorsal
nTPM: 245.0
1840 Male, age 53, unknown 272.5
2464 Female, age 72, unknown 250.0
1831 Male, age 72, unknown 245.4
2850 Male, age 76, both hemispheres 212.2
Periaquaductal grey, lateral
nTPM: 216.2
2053 Male, age 18, unknown 264.9
2140 Male, age 76, both hemispheres 198.0
2272 Male, age 74, both hemispheres 185.7
Pretectal area
nTPM: 266.9
1816 Male, age 51, unknown 330.0
1944 Female, age 72, unknown 325.6
1815 Male, age 53, unknown 309.5
1817 Female, age 42, unknown 301.5
2007 Male, age 72, unknown 279.2
2316 Male, age 76, right hemisphere 256.9
2224 Female, age 72, unknown 252.5
2407 Male, age 75, both hemispheres 228.7
2825 Male, age 18, unknown 226.2
2667 Female, age 75, unknown 214.9
2273 Male, age 74, both hemispheres 210.6
Red nucleus
nTPM: 260.7
2503 Female, age 72, unknown 325.9
2584 Male, age 75, left hemisphere 286.4
1865 Male, age 51, unknown 276.1
1821 Female, age 72, unknown 274.4
2588 Male, age 74, left hemisphere 267.8
2725 Female, age 75, unknown 260.6
1904 Male, age 53, unknown 254.3
2227 Male, age 72, unknown 254.2
2785 Male, age 18, unknown 252.5
2769 Male, age 72, unknown 239.7
2823 Male, age 76, right hemisphere 221.1
1954 Female, age 42, unknown 215.0
Substantia nigra
nTPM: 288.7
2409 Female, age 72, unknown 384.4
2241 Male, age 72, unknown 349.5
1851 Male, age 51, unknown 335.6
2665 Male, age 74, both hemispheres 315.6
1889 Female, age 72, unknown 300.1
1916 Female, age 42, unknown 259.6
2590 Female, age 75, unknown 259.4
2699 Male, age 18, unknown 246.4
1941 Male, age 53, unknown 240.5
2583 Male, age 75, right hemisphere 195.9
Superior colliculus
nTPM: 290.0
2261 Male, age 18, unknown 352.0
2587 Male, age 74, left hemisphere 330.1
1913 Female, age 42, unknown 312.8
2668 Female, age 75, unknown 312.7
2087 Female, age 72, unknown 299.2
1995 Male, age 72, unknown 293.9
1796 Male, age 53, unknown 291.1
1895 Male, age 76, right hemisphere 260.6
1839 Male, age 51, unknown 235.5
2664 Male, age 75, both hemispheres 211.7
Ventral tegmental area
nTPM: 265.7
2410 Female, age 72, unknown 290.2
1915 Female, age 42, unknown 285.9
2223 Female, age 72, unknown 269.3
2021 Male, age 53, unknown 266.5
1942 Male, age 51, unknown 263.2
2218 Male, age 76, both hemispheres 219.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1957.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 1957.3
Samples: 139

Max nTPM: 7841.7
Min nTPM: 735.1
Std nTPM: 929.9
Median nTPM: 1703.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 7841.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 5842.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 4685.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 4208.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 4140.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 3472.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 3471.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 3396.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 3297.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 3259.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 3211.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 3150.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 2961.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 2944.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 2905.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 2805.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 2787.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 2778.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 2741.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 2728.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 2686.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 2655.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 2632.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 2552.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 2525.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 2510.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 2506.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 2491.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 2441.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 2412.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 2399.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 2369.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 2353.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 2338.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 2331.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 2268.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 2247.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 2225.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 2219.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 2195.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 2192.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 2153.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 2136.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 2119.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 2067.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 2029.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 2027.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 2013.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 2004.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1999.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 1976.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 1925.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1916.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 1916.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 1912.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1905.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1901.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1896.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 1891.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 1881.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 1876.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 1866.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 1847.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 1834.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1828.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 1795.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 1745.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 1732.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 1719.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 1703.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1684.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 1670.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1663.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 1662.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 1648.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 1644.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 1637.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 1636.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 1630.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 1606.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1601.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 1599.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 1569.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 1556.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 1547.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 1542.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 1535.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 1525.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 1519.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 1510.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 1478.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 1477.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 1476.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1464.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 1453.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 1441.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 1441.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 1439.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 1434.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 1413.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 1398.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 1392.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 1388.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 1382.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 1380.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 1371.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 1364.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 1357.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 1347.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 1330.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 1330.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 1303.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 1284.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 1278.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 1275.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 1269.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 1264.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1259.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 1250.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 1242.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 1242.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 1237.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 1230.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 1219.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 1215.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 1182.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 1153.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 1144.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 1105.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 1073.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 1068.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 1042.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 992.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 984.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 945.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 941.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 920.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 834.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 735.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

29.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 29.8
FF:10158-103A5 76 years, female 29.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

559.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 559.6
Samples: 4

Max nTPM: 775.7
Min nTPM: 413.6
Sample A Female 775.7
Sample B Female 593.0
Sample C Male 456.0
Sample D Male 413.6
Midbrain
nTPM: 541.2
Samples: 4

Max nTPM: 732.3
Min nTPM: 377.8
Sample A Female 732.3
Sample B Female 614.7
Sample C Male 440.1
Sample D Male 377.8
Periaqueductal gray
nTPM: 436.9
Samples: 3

Max nTPM: 466.1
Min nTPM: 401.1
Sample B Female 466.1
Sample C Male 443.5
Sample D Male 401.1
Superior colliculi
nTPM: 554.4
Samples: 4

Max nTPM: 669.5
Min nTPM: 481.3
Sample A Female 669.5
Sample B Female 532.2
Sample C Male 534.6
Sample D Male 481.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

624.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 624.6
Samples: 4

Max nTPM: 673.9
Min nTPM: 591.7
Sample A Male 673.9
Sample B Male 609.4
Sample C Female 591.7
Sample D Female 623.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

4.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.7
68744869 Antisense, RP_050208_01_G10, Mouse strain C57BL/6J (56 days, male) 4.7

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