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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:200.1 nTPM
HPA Brain:361.8 nTPM
GTEx:200.1 nTPM
FANTOM5:1082.0 Scaled Tags Per Million
Pig:422.6 nTPM
Mouse:338.8 nTPM
Allen mouse:7.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

361.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 251.8
2586 Male, age 75, left hemisphere 283.6
2666 Male, age 74, left hemisphere 270.1
1870 Female, age 42, unknown 260.6
2019 Male, age 18, unknown 258.4
2411 Female, age 72, unknown 249.2
1827 Male, age 72, unknown 244.4
2219 Male, age 76, both hemispheres 242.8
2828 Female, age 72, unknown 241.2
1833 Male, age 53, unknown 238.8
1830 Male, age 51, unknown 228.8
Dorsal raphe nucleus
nTPM: 298.3
2047 Male, age 72, unknown 382.5
2750 Male, age 76, both hemispheres 305.7
2298 Female, age 72, unknown 292.0
1828 Male, age 53, unknown 272.8
2016 Female, age 72, unknown 238.5
Inferior colliculus
nTPM: 234.1
1890 Male, age 53, unknown 245.9
2097 Female, age 72, unknown 233.7
1848 Female, age 42, unknown 231.7
2849 Male, age 72, unknown 225.0
Median raphe nucleus
nTPM: 361.8
2220 Male, age 76, midline 361.8
Periaquaductal grey, anterior
nTPM: 248.1
1947 Male, age 18, unknown 274.7
1795 Male, age 51, unknown 243.6
2502 Female, age 75, unknown 225.8
Periaquaductal grey, dorsal
nTPM: 245.0
2850 Male, age 76, both hemispheres 275.8
1840 Male, age 53, unknown 250.6
1831 Male, age 72, unknown 241.1
2464 Female, age 72, unknown 212.3
Periaquaductal grey, lateral
nTPM: 229.3
2053 Male, age 18, unknown 232.5
2140 Male, age 76, both hemispheres 227.8
2272 Male, age 74, both hemispheres 227.5
Pretectal area
nTPM: 265.1
1817 Female, age 42, unknown 311.8
1816 Male, age 51, unknown 309.9
1944 Female, age 72, unknown 300.6
1815 Male, age 53, unknown 296.7
2007 Male, age 72, unknown 283.7
2667 Female, age 75, unknown 269.7
2407 Male, age 75, both hemispheres 256.3
2273 Male, age 74, both hemispheres 230.6
2825 Male, age 18, unknown 227.4
2224 Female, age 72, unknown 227.3
2316 Male, age 76, right hemisphere 202.1
Red nucleus
nTPM: 257.4
1821 Female, age 72, unknown 313.6
2725 Female, age 75, unknown 305.2
1954 Female, age 42, unknown 261.4
2503 Female, age 72, unknown 260.4
1865 Male, age 51, unknown 258.1
1904 Male, age 53, unknown 258.1
2584 Male, age 75, left hemisphere 253.4
2785 Male, age 18, unknown 251.4
2588 Male, age 74, left hemisphere 249.9
2769 Male, age 72, unknown 230.2
2227 Male, age 72, unknown 223.8
2823 Male, age 76, right hemisphere 222.7
Substantia nigra
nTPM: 305.7
1916 Female, age 42, unknown 367.2
2241 Male, age 72, unknown 331.0
1851 Male, age 51, unknown 329.3
2665 Male, age 74, both hemispheres 317.2
1941 Male, age 53, unknown 305.4
1889 Female, age 72, unknown 300.1
2409 Female, age 72, unknown 299.6
2699 Male, age 18, unknown 292.8
2583 Male, age 75, right hemisphere 275.1
2590 Female, age 75, unknown 239.5
Superior colliculus
nTPM: 252.3
2664 Male, age 75, both hemispheres 295.8
2668 Female, age 75, unknown 284.9
2087 Female, age 72, unknown 265.7
2261 Male, age 18, unknown 264.4
1796 Male, age 53, unknown 246.6
2587 Male, age 74, left hemisphere 242.5
1913 Female, age 42, unknown 240.6
1895 Male, age 76, right hemisphere 229.7
1839 Male, age 51, unknown 226.1
1995 Male, age 72, unknown 226.1
Ventral tegmental area
nTPM: 276.2
1915 Female, age 42, unknown 296.3
2218 Male, age 76, both hemispheres 296.2
2223 Female, age 72, unknown 274.8
2410 Female, age 72, unknown 267.0
1942 Male, age 51, unknown 264.9
2021 Male, age 53, unknown 258.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

200.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 200.1
Samples: 139

Max nTPM: 313.1
Min nTPM: 124.8
Std nTPM: 32.3
Median nTPM: 200.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 313.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 307.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 290.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 268.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 267.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 261.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 259.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 257.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 252.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 249.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 246.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 245.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 244.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 241.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 236.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 235.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 233.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 232.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 232.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 231.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 227.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 226.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 225.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 225.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 225.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 224.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 224.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 223.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 222.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 222.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 222.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 220.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 218.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 218.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 217.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 217.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 216.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 216.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 215.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 214.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 213.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 213.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 212.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 212.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 212.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 211.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 211.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 210.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 209.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 208.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 208.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 208.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 206.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 205.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 205.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 205.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 204.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 203.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 202.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 202.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 202.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 201.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 201.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 201.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 201.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 201.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 200.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 200.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 200.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 200.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 198.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 198.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 197.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 197.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 197.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 197.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 197.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 196.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 196.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 194.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 192.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 191.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 190.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 189.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 189.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 188.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 188.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 187.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 187.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 187.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 185.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 185.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 185.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 185.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 183.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 183.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 183.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 182.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 182.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 182.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 181.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 180.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 180.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 179.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 179.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 177.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 177.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 176.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 175.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 175.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 174.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 174.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 173.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 173.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 172.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 171.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 169.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 169.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 169.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 168.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 165.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 164.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 161.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 160.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 159.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 159.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 159.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 158.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 157.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 157.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 153.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 152.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 151.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 150.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 148.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 146.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 133.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 132.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 124.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

1082.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 1082.0
FF:10158-103A5 76 years, female 1082.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

422.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 361.2
Samples: 4

Max nTPM: 413.0
Min nTPM: 321.4
Sample A Female 413.0
Sample B Female 338.7
Sample C Male 371.6
Sample D Male 321.4
Midbrain
nTPM: 400.1
Samples: 4

Max nTPM: 482.5
Min nTPM: 327.9
Sample A Female 482.5
Sample B Female 359.8
Sample C Male 430.0
Sample D Male 327.9
Periaqueductal gray
nTPM: 323.2
Samples: 3

Max nTPM: 339.7
Min nTPM: 310.0
Sample B Female 319.8
Sample C Male 339.7
Sample D Male 310.0
Superior colliculi
nTPM: 422.6
Samples: 4

Max nTPM: 438.8
Min nTPM: 398.2
Sample A Female 427.5
Sample B Female 426.0
Sample C Male 438.8
Sample D Male 398.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

338.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 338.8
Samples: 4

Max nTPM: 355.1
Min nTPM: 316.3
Sample A Male 316.3
Sample B Male 347.4
Sample C Female 355.1
Sample D Female 336.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

7.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 7.4
69671965 Antisense, RP_050428_02_G01, Mouse strain C57BL/6J (56 days, male) 14.8
70795766 Antisense, RP_050712_01_H11, Mouse strain C57BL/6J (56 days, male) 0.1

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