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TISSUE PRIMARY DATA MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN NASOPHARYNX
ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
ANTIBODIES
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VALIDATION
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:76.2 nTPM
HPA Brain:732.5 nTPM
GTEx:76.2 nTPM
FANTOM5:65.0 Scaled Tags Per Million
Pig:329.3 nTPM
Mouse:255.2 nTPM
Allen mouse:8.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

732.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 428.2
2586 Male, age 75, left hemisphere 824.9
2828 Female, age 72, unknown 465.8
1827 Male, age 72, unknown 446.6
2219 Male, age 76, both hemispheres 412.1
1833 Male, age 53, unknown 406.6
2019 Male, age 18, unknown 368.1
2666 Male, age 74, left hemisphere 353.2
1830 Male, age 51, unknown 343.9
1870 Female, age 42, unknown 341.4
2411 Female, age 72, unknown 319.2
Dorsal raphe nucleus
nTPM: 459.0
2047 Male, age 72, unknown 569.5
1828 Male, age 53, unknown 547.2
2016 Female, age 72, unknown 429.5
2298 Female, age 72, unknown 412.2
2750 Male, age 76, both hemispheres 336.6
Inferior colliculus
nTPM: 732.5
1848 Female, age 42, unknown 897.5
2097 Female, age 72, unknown 704.5
1890 Male, age 53, unknown 664.1
2849 Male, age 72, unknown 663.9
Median raphe nucleus
nTPM: 306.8
2220 Male, age 76, midline 306.8
Periaquaductal grey, anterior
nTPM: 472.7
2502 Female, age 75, unknown 577.7
1947 Male, age 18, unknown 449.9
1795 Male, age 51, unknown 390.4
Periaquaductal grey, dorsal
nTPM: 480.3
1840 Male, age 53, unknown 615.8
2464 Female, age 72, unknown 610.3
2850 Male, age 76, both hemispheres 429.8
1831 Male, age 72, unknown 265.2
Periaquaductal grey, lateral
nTPM: 367.5
2140 Male, age 76, both hemispheres 477.3
2053 Male, age 18, unknown 421.8
2272 Male, age 74, both hemispheres 203.3
Pretectal area
nTPM: 439.4
1817 Female, age 42, unknown 660.9
1816 Male, age 51, unknown 534.3
2007 Male, age 72, unknown 500.8
1944 Female, age 72, unknown 458.3
2667 Female, age 75, unknown 455.2
2825 Male, age 18, unknown 450.1
1815 Male, age 53, unknown 440.3
2316 Male, age 76, right hemisphere 414.6
2224 Female, age 72, unknown 394.2
2407 Male, age 75, both hemispheres 296.1
2273 Male, age 74, both hemispheres 228.8
Red nucleus
nTPM: 494.3
1821 Female, age 72, unknown 645.6
1954 Female, age 42, unknown 630.9
2769 Male, age 72, unknown 630.5
2227 Male, age 72, unknown 606.3
2588 Male, age 74, left hemisphere 599.2
2503 Female, age 72, unknown 508.0
1865 Male, age 51, unknown 488.4
2823 Male, age 76, right hemisphere 483.2
1904 Male, age 53, unknown 475.8
2785 Male, age 18, unknown 324.5
2725 Female, age 75, unknown 309.4
2584 Male, age 75, left hemisphere 230.1
Substantia nigra
nTPM: 408.3
1916 Female, age 42, unknown 618.7
1889 Female, age 72, unknown 564.4
2699 Male, age 18, unknown 455.8
2241 Male, age 72, unknown 437.0
1851 Male, age 51, unknown 394.5
2665 Male, age 74, both hemispheres 381.2
1941 Male, age 53, unknown 329.9
2583 Male, age 75, right hemisphere 308.2
2409 Female, age 72, unknown 301.4
2590 Female, age 75, unknown 292.1
Superior colliculus
nTPM: 444.7
2668 Female, age 75, unknown 664.9
1895 Male, age 76, right hemisphere 535.8
2087 Female, age 72, unknown 499.3
2664 Male, age 75, both hemispheres 498.9
1839 Male, age 51, unknown 485.6
2261 Male, age 18, unknown 482.7
1796 Male, age 53, unknown 419.0
2587 Male, age 74, left hemisphere 328.4
1913 Female, age 42, unknown 271.0
1995 Male, age 72, unknown 261.9
Ventral tegmental area
nTPM: 346.4
2410 Female, age 72, unknown 408.0
1915 Female, age 42, unknown 388.3
2223 Female, age 72, unknown 368.8
1942 Male, age 51, unknown 332.8
2218 Male, age 76, both hemispheres 309.6
2021 Male, age 53, unknown 270.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

76.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 76.2
Samples: 139

Max nTPM: 249.5
Min nTPM: 5.4
Std nTPM: 53.4
Median nTPM: 62.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 249.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 234.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 230.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 229.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 225.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 193.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 192.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 180.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 179.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 175.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 173.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 161.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 158.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 156.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 155.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 149.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 140.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 133.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 132.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 132.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 130.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 130.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 129.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 126.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 126.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 121.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 119.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 114.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 112.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 111.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 110.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 109.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 108.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 104.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 101.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 99.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 97.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 96.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 95.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 94.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 94.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 93.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 91.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 90.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 86.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 85.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 85.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 84.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 81.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 81.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 81.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 80.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 80.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 80.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 77.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 76.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 75.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 74.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 72.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 70.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 69.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 69.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 69.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 68.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 68.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 66.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 66.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 64.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 62.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 62.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 58.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 58.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 58.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 58.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 55.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 54.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 53.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 52.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 52.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 52.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 52.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 51.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 50.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 50.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 49.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 48.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 48.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 47.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 46.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 46.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 46.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 46.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 46.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 45.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 43.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 42.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 40.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 40.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 38.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 37.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 36.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 36.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 35.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 34.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 34.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 34.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 34.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 33.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 32.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 32.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 31.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 31.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 31.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 31.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 30.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 30.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 29.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 29.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 26.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 26.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 25.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 25.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 22.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 22.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 21.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 20.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 19.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 19.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 18.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 17.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 17.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 17.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 16.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 15.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 14.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 13.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 12.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 10.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 5.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

65.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 65.0
FF:10158-103A5 76 years, female 65.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

329.3
Pig sample Sample description nTPM
Substantia nigra
nTPM: 253.0
Samples: 4

Max nTPM: 275.8
Min nTPM: 207.5
Sample A Female 265.7
Sample B Female 207.5
Sample C Male 275.8
Sample D Male 262.9
Midbrain
nTPM: 329.3
Samples: 4

Max nTPM: 504.4
Min nTPM: 125.3
Sample A Female 125.3
Sample B Female 399.9
Sample C Male 504.4
Sample D Male 287.5
Periaqueductal gray
nTPM: 300.6
Samples: 3

Max nTPM: 421.3
Min nTPM: 222.6
Sample B Female 421.3
Sample C Male 257.9
Sample D Male 222.6
Superior colliculi
nTPM: 302.4
Samples: 4

Max nTPM: 403.7
Min nTPM: 193.0
Sample A Female 287.0
Sample B Female 193.0
Sample C Male 403.7
Sample D Male 325.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

255.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 255.2
Samples: 4

Max nTPM: 265.0
Min nTPM: 233.4
Sample A Male 233.4
Sample B Male 265.0
Sample C Female 259.2
Sample D Female 263.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

8.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 8.3
73521823 Antisense, RP_051101_03_B07, Mouse strain C57BL/6J (56 days, male) 8.8
69873839 Antisense, RP_050512_02_B03, Mouse strain C57BL/6J (56 days, male) 7.8

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.


contact@proteinatlas.org