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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:309.0 nTPM
HPA Brain:342.7 nTPM
GTEx:309.0 nTPM
FANTOM5:227.2 Scaled Tags Per Million
Pig:0.0 nTPM
Mouse:1424.0 nTPM
Allen mouse:25.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

342.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 248.3
2019 Male, age 18, unknown 359.7
2411 Female, age 72, unknown 295.9
2219 Male, age 76, both hemispheres 292.6
1827 Male, age 72, unknown 291.2
2828 Female, age 72, unknown 240.6
1870 Female, age 42, unknown 224.6
1833 Male, age 53, unknown 219.0
2666 Male, age 74, left hemisphere 203.0
1830 Male, age 51, unknown 188.5
2586 Male, age 75, left hemisphere 168.1
Dorsal raphe nucleus
nTPM: 290.6
2298 Female, age 72, unknown 401.5
1828 Male, age 53, unknown 309.1
2750 Male, age 76, both hemispheres 266.0
2047 Male, age 72, unknown 262.7
2016 Female, age 72, unknown 213.7
Inferior colliculus
nTPM: 280.0
2097 Female, age 72, unknown 389.4
1890 Male, age 53, unknown 285.2
1848 Female, age 42, unknown 248.3
2849 Male, age 72, unknown 197.0
Median raphe nucleus
nTPM: 254.7
2220 Male, age 76, midline 254.7
Periaquaductal grey, anterior
nTPM: 265.7
1947 Male, age 18, unknown 284.4
1795 Male, age 51, unknown 267.9
2502 Female, age 75, unknown 244.8
Periaquaductal grey, dorsal
nTPM: 214.4
2464 Female, age 72, unknown 219.8
1840 Male, age 53, unknown 216.3
2850 Male, age 76, both hemispheres 211.5
1831 Male, age 72, unknown 209.9
Periaquaductal grey, lateral
nTPM: 246.0
2272 Male, age 74, both hemispheres 337.3
2140 Male, age 76, both hemispheres 201.1
2053 Male, age 18, unknown 199.7
Pretectal area
nTPM: 332.2
2007 Male, age 72, unknown 445.0
1816 Male, age 51, unknown 441.9
1817 Female, age 42, unknown 434.9
1944 Female, age 72, unknown 414.4
2667 Female, age 75, unknown 363.8
2273 Male, age 74, both hemispheres 346.1
1815 Male, age 53, unknown 337.7
2224 Female, age 72, unknown 280.8
2316 Male, age 76, right hemisphere 236.5
2825 Male, age 18, unknown 204.8
2407 Male, age 75, both hemispheres 148.3
Red nucleus
nTPM: 270.5
1821 Female, age 72, unknown 387.0
2785 Male, age 18, unknown 319.7
2725 Female, age 75, unknown 317.7
2503 Female, age 72, unknown 297.3
2823 Male, age 76, right hemisphere 264.0
1954 Female, age 42, unknown 263.7
1904 Male, age 53, unknown 257.7
1865 Male, age 51, unknown 256.6
2769 Male, age 72, unknown 252.9
2227 Male, age 72, unknown 251.8
2588 Male, age 74, left hemisphere 216.3
2584 Male, age 75, left hemisphere 162.0
Substantia nigra
nTPM: 342.7
1916 Female, age 42, unknown 481.0
1851 Male, age 51, unknown 403.7
1889 Female, age 72, unknown 401.4
1941 Male, age 53, unknown 390.3
2241 Male, age 72, unknown 384.7
2665 Male, age 74, both hemispheres 329.3
2409 Female, age 72, unknown 325.6
2699 Male, age 18, unknown 267.1
2590 Female, age 75, unknown 253.6
2583 Male, age 75, right hemisphere 190.8
Superior colliculus
nTPM: 253.6
2087 Female, age 72, unknown 376.3
2261 Male, age 18, unknown 291.6
1796 Male, age 53, unknown 280.8
1895 Male, age 76, right hemisphere 279.4
2587 Male, age 74, left hemisphere 267.5
2668 Female, age 75, unknown 251.8
1913 Female, age 42, unknown 227.1
1839 Male, age 51, unknown 220.3
1995 Male, age 72, unknown 209.4
2664 Male, age 75, both hemispheres 131.5
Ventral tegmental area
nTPM: 299.7
2410 Female, age 72, unknown 418.1
1915 Female, age 42, unknown 362.4
2218 Male, age 76, both hemispheres 361.6
1942 Male, age 51, unknown 246.7
2223 Female, age 72, unknown 212.5
2021 Male, age 53, unknown 196.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

309.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 309.0
Samples: 139

Max nTPM: 834.4
Min nTPM: 125.9
Std nTPM: 133.4
Median nTPM: 270.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 834.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 826.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 758.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 674.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 612.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 611.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 608.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 532.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 511.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 498.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 496.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 486.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 485.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 470.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 470.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 466.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 463.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 454.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 453.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 446.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 445.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 438.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 432.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 428.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 426.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 419.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 419.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 416.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 415.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 402.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 397.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 395.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 394.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 390.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 380.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 377.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 364.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 362.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 357.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 357.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 356.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 344.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 341.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 336.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 334.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 329.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 326.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 318.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 314.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 305.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 304.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 303.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 302.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 298.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 297.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 297.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 296.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 294.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 290.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 290.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 287.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 286.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 285.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 284.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 283.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 280.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 277.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 275.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 274.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 270.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 270.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 269.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 269.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 268.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 265.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 265.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 261.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 261.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 260.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 258.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 255.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 254.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 253.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 251.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 250.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 249.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 245.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 238.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 238.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 237.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 236.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 236.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 234.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 234.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 233.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 230.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 230.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 229.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 225.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 224.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 219.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 217.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 215.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 215.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 213.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 213.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 211.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 210.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 209.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 207.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 206.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 206.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 202.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 202.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 200.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 195.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 193.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 192.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 191.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 191.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 190.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 189.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 188.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 184.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 182.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 181.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 178.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 171.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 171.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 171.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 161.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 160.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 159.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 150.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 140.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 140.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 137.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 136.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 125.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

227.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 227.2
FF:10158-103A5 76 years, female 227.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

0.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 0.0
Samples: 4

Max nTPM: 0.0
Min nTPM: 0.0
Sample A Female 0.0
Sample B Female 0.0
Sample C Male 0.0
Sample D Male 0.0
Midbrain
nTPM: 0.0
Samples: 4

Max nTPM: 0.0
Min nTPM: 0.0
Sample A Female 0.0
Sample B Female 0.0
Sample C Male 0.0
Sample D Male 0.0
Periaqueductal gray
nTPM: 0.0
Samples: 3

Max nTPM: 0.0
Min nTPM: 0.0
Sample B Female 0.0
Sample C Male 0.0
Sample D Male 0.0
Superior colliculi
nTPM: 0.0
Samples: 4

Max nTPM: 0.0
Min nTPM: 0.0
Sample A Female 0.0
Sample B Female 0.0
Sample C Male 0.0
Sample D Male 0.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1424.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 1424.0
Samples: 4

Max nTPM: 1445.5
Min nTPM: 1385.1
Sample A Male 1445.5
Sample B Male 1428.4
Sample C Female 1385.1
Sample D Female 1436.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

25.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 25.7
70528264 Antisense, RP_050623_02_C01, Mouse strain C57BL/6J (56 days, male) 25.7

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