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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:442.1 nTPM
HPA Brain:340.1 nTPM
GTEx:442.1 nTPM
FANTOM5:21.0 Scaled Tags Per Million
Pig:441.9 nTPM
Mouse:840.3 nTPM
Allen mouse:20.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

340.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 245.6
2019 Male, age 18, unknown 317.4
1827 Male, age 72, unknown 283.6
2666 Male, age 74, left hemisphere 269.7
2411 Female, age 72, unknown 267.7
2586 Male, age 75, left hemisphere 256.8
2219 Male, age 76, both hemispheres 246.1
2828 Female, age 72, unknown 237.8
1870 Female, age 42, unknown 206.8
1833 Male, age 53, unknown 195.2
1830 Male, age 51, unknown 175.4
Dorsal raphe nucleus
nTPM: 251.1
2298 Female, age 72, unknown 328.5
1828 Male, age 53, unknown 269.8
2047 Male, age 72, unknown 247.2
2750 Male, age 76, both hemispheres 237.7
2016 Female, age 72, unknown 172.0
Inferior colliculus
nTPM: 231.2
2097 Female, age 72, unknown 305.3
1890 Male, age 53, unknown 243.7
1848 Female, age 42, unknown 203.3
2849 Male, age 72, unknown 172.3
Median raphe nucleus
nTPM: 280.5
2220 Male, age 76, midline 280.5
Periaquaductal grey, anterior
nTPM: 259.4
1795 Male, age 51, unknown 291.8
1947 Male, age 18, unknown 245.5
2502 Female, age 75, unknown 240.8
Periaquaductal grey, dorsal
nTPM: 203.3
1831 Male, age 72, unknown 210.2
2464 Female, age 72, unknown 203.9
2850 Male, age 76, both hemispheres 200.1
1840 Male, age 53, unknown 199.0
Periaquaductal grey, lateral
nTPM: 190.5
2272 Male, age 74, both hemispheres 198.4
2053 Male, age 18, unknown 186.8
2140 Male, age 76, both hemispheres 186.2
Pretectal area
nTPM: 340.1
1816 Male, age 51, unknown 560.7
1944 Female, age 72, unknown 496.0
1817 Female, age 42, unknown 473.6
2007 Male, age 72, unknown 439.5
1815 Male, age 53, unknown 365.6
2667 Female, age 75, unknown 353.6
2224 Female, age 72, unknown 246.9
2273 Male, age 74, both hemispheres 221.4
2316 Male, age 76, right hemisphere 204.8
2825 Male, age 18, unknown 201.1
2407 Male, age 75, both hemispheres 177.9
Red nucleus
nTPM: 240.7
2785 Male, age 18, unknown 308.4
1821 Female, age 72, unknown 297.3
2725 Female, age 75, unknown 255.1
2588 Male, age 74, left hemisphere 247.7
2503 Female, age 72, unknown 238.1
1954 Female, age 42, unknown 235.2
1865 Male, age 51, unknown 231.4
2823 Male, age 76, right hemisphere 227.8
1904 Male, age 53, unknown 223.4
2769 Male, age 72, unknown 218.8
2227 Male, age 72, unknown 217.4
2584 Male, age 75, left hemisphere 188.4
Substantia nigra
nTPM: 300.7
1916 Female, age 42, unknown 414.9
1889 Female, age 72, unknown 389.9
2665 Male, age 74, both hemispheres 324.7
2241 Male, age 72, unknown 323.4
1851 Male, age 51, unknown 321.7
1941 Male, age 53, unknown 309.7
2409 Female, age 72, unknown 274.8
2699 Male, age 18, unknown 223.1
2590 Female, age 75, unknown 221.5
2583 Male, age 75, right hemisphere 203.8
Superior colliculus
nTPM: 261.2
2087 Female, age 72, unknown 439.1
2261 Male, age 18, unknown 327.6
2668 Female, age 75, unknown 297.5
1796 Male, age 53, unknown 288.2
1913 Female, age 42, unknown 251.3
2587 Male, age 74, left hemisphere 223.8
1895 Male, age 76, right hemisphere 213.7
1995 Male, age 72, unknown 210.3
1839 Male, age 51, unknown 185.8
2664 Male, age 75, both hemispheres 174.6
Ventral tegmental area
nTPM: 261.5
2410 Female, age 72, unknown 302.7
1915 Female, age 42, unknown 302.1
2218 Male, age 76, both hemispheres 286.5
2223 Female, age 72, unknown 241.9
1942 Male, age 51, unknown 225.7
2021 Male, age 53, unknown 210.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

442.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 442.1
Samples: 139

Max nTPM: 886.7
Min nTPM: 210.4
Std nTPM: 143.1
Median nTPM: 415.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 886.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 868.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 818.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 813.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 800.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 729.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 723.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 716.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 699.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 670.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 657.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 653.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 638.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 636.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 631.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 618.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 618.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 613.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 613.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 611.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 608.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 604.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 604.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 598.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 594.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 584.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 576.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 570.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 567.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 562.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 561.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 548.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 538.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 527.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 517.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 515.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 514.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 507.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 505.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 498.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 497.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 478.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 477.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 474.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 474.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 469.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 469.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 468.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 462.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 459.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 459.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 458.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 456.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 453.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 452.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 446.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 445.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 444.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 437.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 430.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 429.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 427.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 425.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 423.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 421.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 421.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 420.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 418.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 416.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 415.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 413.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 411.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 410.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 403.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 400.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 398.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 397.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 395.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 390.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 383.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 383.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 382.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 382.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 382.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 379.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 378.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 377.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 377.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 377.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 373.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 372.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 370.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 369.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 367.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 367.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 367.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 363.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 362.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 361.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 358.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 357.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 357.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 355.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 354.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 347.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 342.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 339.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 337.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 335.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 335.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 329.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 320.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 317.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 316.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 315.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 312.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 303.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 303.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 299.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 291.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 291.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 287.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 279.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 278.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 275.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 275.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 274.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 273.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 267.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 262.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 261.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 258.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 247.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 232.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 224.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 222.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 221.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 218.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 210.4
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

21.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 21.0
FF:10158-103A5 76 years, female 21.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

441.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 350.8
Samples: 4

Max nTPM: 467.3
Min nTPM: 240.4
Sample A Female 467.3
Sample B Female 273.5
Sample C Male 421.8
Sample D Male 240.4
Midbrain
nTPM: 395.6
Samples: 4

Max nTPM: 510.1
Min nTPM: 310.4
Sample A Female 310.4
Sample B Female 358.9
Sample C Male 510.1
Sample D Male 402.9
Periaqueductal gray
nTPM: 326.1
Samples: 3

Max nTPM: 383.4
Min nTPM: 278.0
Sample B Female 316.8
Sample C Male 383.4
Sample D Male 278.0
Superior colliculi
nTPM: 442.0
Samples: 4

Max nTPM: 553.8
Min nTPM: 309.1
Sample A Female 486.2
Sample B Female 309.1
Sample C Male 553.8
Sample D Male 418.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

840.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 840.4
Samples: 4

Max nTPM: 883.7
Min nTPM: 805.5
Sample A Male 834.1
Sample B Male 838.1
Sample C Female 805.5
Sample D Female 883.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

20.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 20.2
70191997 Antisense, RP_050517_01_A08, Mouse strain C57BL/6J (56 days, male) 20.2

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