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C12orf57
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TISSUE PRIMARY DATA MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN NASOPHARYNX
ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
ANTIBODIES
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VALIDATION
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:245.9 nTPM
HPA Brain:129.0 nTPM
GTEx:245.9 nTPM
FANTOM5:75.1 Scaled Tags Per Million
Pig:44.0 nTPM
Mouse:33.7 nTPM
Allen mouse:2.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

129.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 102.9
2586 Male, age 75, left hemisphere 126.8
2411 Female, age 72, unknown 114.0
1827 Male, age 72, unknown 109.6
1870 Female, age 42, unknown 107.7
2019 Male, age 18, unknown 102.8
1833 Male, age 53, unknown 99.4
2219 Male, age 76, both hemispheres 97.5
1830 Male, age 51, unknown 92.5
2666 Male, age 74, left hemisphere 89.8
2828 Female, age 72, unknown 88.8
Dorsal raphe nucleus
nTPM: 112.2
2298 Female, age 72, unknown 134.7
2047 Male, age 72, unknown 113.3
1828 Male, age 53, unknown 107.3
2750 Male, age 76, both hemispheres 105.7
2016 Female, age 72, unknown 100.2
Inferior colliculus
nTPM: 129.0
2097 Female, age 72, unknown 139.5
1848 Female, age 42, unknown 129.4
2849 Male, age 72, unknown 125.9
1890 Male, age 53, unknown 121.2
Median raphe nucleus
nTPM: 104.9
2220 Male, age 76, midline 104.9
Periaquaductal grey, anterior
nTPM: 123.3
2502 Female, age 75, unknown 142.0
1947 Male, age 18, unknown 119.0
1795 Male, age 51, unknown 109.0
Periaquaductal grey, dorsal
nTPM: 99.6
1840 Male, age 53, unknown 106.5
2464 Female, age 72, unknown 105.4
2850 Male, age 76, both hemispheres 96.3
1831 Male, age 72, unknown 90.0
Periaquaductal grey, lateral
nTPM: 88.9
2140 Male, age 76, both hemispheres 97.1
2053 Male, age 18, unknown 85.5
2272 Male, age 74, both hemispheres 84.2
Pretectal area
nTPM: 102.4
2224 Female, age 72, unknown 125.9
1817 Female, age 42, unknown 119.7
2007 Male, age 72, unknown 113.9
2316 Male, age 76, right hemisphere 111.6
2825 Male, age 18, unknown 109.7
1816 Male, age 51, unknown 106.2
1944 Female, age 72, unknown 102.5
1815 Male, age 53, unknown 96.7
2667 Female, age 75, unknown 90.2
2273 Male, age 74, both hemispheres 82.5
2407 Male, age 75, both hemispheres 66.9
Red nucleus
nTPM: 106.0
2503 Female, age 72, unknown 122.6
1821 Female, age 72, unknown 118.2
2588 Male, age 74, left hemisphere 115.1
2785 Male, age 18, unknown 115.0
2227 Male, age 72, unknown 113.2
2769 Male, age 72, unknown 112.8
2725 Female, age 75, unknown 103.8
1904 Male, age 53, unknown 98.2
1954 Female, age 42, unknown 97.6
1865 Male, age 51, unknown 95.1
2823 Male, age 76, right hemisphere 91.0
2584 Male, age 75, left hemisphere 89.6
Substantia nigra
nTPM: 98.6
1916 Female, age 42, unknown 124.2
1851 Male, age 51, unknown 115.2
2665 Male, age 74, both hemispheres 110.0
1889 Female, age 72, unknown 106.6
2699 Male, age 18, unknown 97.5
2241 Male, age 72, unknown 95.8
1941 Male, age 53, unknown 93.8
2590 Female, age 75, unknown 89.6
2583 Male, age 75, right hemisphere 79.1
2409 Female, age 72, unknown 74.1
Superior colliculus
nTPM: 101.9
1796 Male, age 53, unknown 123.7
1895 Male, age 76, right hemisphere 116.9
2587 Male, age 74, left hemisphere 111.8
2668 Female, age 75, unknown 107.8
1839 Male, age 51, unknown 106.3
2664 Male, age 75, both hemispheres 99.4
2087 Female, age 72, unknown 93.2
2261 Male, age 18, unknown 90.5
1913 Female, age 42, unknown 86.8
1995 Male, age 72, unknown 82.3
Ventral tegmental area
nTPM: 109.6
1915 Female, age 42, unknown 120.3
1942 Male, age 51, unknown 115.3
2021 Male, age 53, unknown 110.4
2410 Female, age 72, unknown 107.7
2218 Male, age 76, both hemispheres 103.7
2223 Female, age 72, unknown 100.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

245.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 245.9
Samples: 139

Max nTPM: 614.4
Min nTPM: 140.6
Std nTPM: 72.3
Median nTPM: 233.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 614.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 505.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 478.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 470.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 395.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 367.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 365.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 357.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 355.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 348.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 347.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 341.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 340.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 338.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 325.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 322.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 319.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 317.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 311.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 307.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 304.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 301.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 297.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 295.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 294.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 292.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 291.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 290.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 286.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 284.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 282.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 281.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 281.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 278.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 277.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 274.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 274.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 273.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 273.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 272.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 271.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 270.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 269.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 264.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 264.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 262.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 260.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 260.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 257.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 257.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 256.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 256.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 255.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 254.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 253.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 250.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 246.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 245.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 244.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 242.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 242.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 240.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 240.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 240.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 239.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 236.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 236.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 235.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 234.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 233.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 232.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 232.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 231.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 231.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 230.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 230.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 230.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 227.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 227.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 223.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 223.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 222.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 220.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 218.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 217.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 216.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 216.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 215.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 214.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 211.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 211.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 209.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 209.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 209.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 208.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 207.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 207.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 205.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 202.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 202.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 202.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 201.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 200.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 199.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 198.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 195.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 194.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 194.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 194.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 193.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 193.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 193.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 191.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 190.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 188.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 185.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 184.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 184.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 184.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 176.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 175.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 172.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 170.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 170.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 166.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 166.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 165.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 161.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 158.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 158.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 158.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 157.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 154.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 154.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 153.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 151.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 148.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 143.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 140.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

75.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 75.1
FF:10158-103A5 76 years, female 75.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

44.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 34.2
Samples: 4

Max nTPM: 55.7
Min nTPM: 15.2
Sample A Female 55.7
Sample B Female 34.6
Sample C Male 31.4
Sample D Male 15.2
Midbrain
nTPM: 35.2
Samples: 4

Max nTPM: 38.5
Min nTPM: 31.0
Sample A Female 33.8
Sample B Female 38.5
Sample C Male 37.4
Sample D Male 31.0
Periaqueductal gray
nTPM: 25.5
Samples: 3

Max nTPM: 30.2
Min nTPM: 19.4
Sample B Female 30.2
Sample C Male 26.9
Sample D Male 19.4
Superior colliculi
nTPM: 44.0
Samples: 4

Max nTPM: 63.9
Min nTPM: 28.2
Sample A Female 63.9
Sample B Female 47.5
Sample C Male 36.5
Sample D Male 28.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

33.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 33.8
Samples: 4

Max nTPM: 46.1
Min nTPM: 24.7
Sample A Male 46.1
Sample B Male 28.6
Sample C Female 24.7
Sample D Female 35.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

2.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.1
386251 Antisense, RP_040804_01_E02, Mouse strain C57BL/6J (56 days, male) 2.1

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