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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:52.7 nTPM
HPA Brain:232.8 nTPM
GTEx:52.7 nTPM
FANTOM5:305.2 Scaled Tags Per Million
Pig:233.2 nTPM
Mouse:155.1 nTPM
Allen mouse:14.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

232.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 177.8
2411 Female, age 72, unknown 218.7
2666 Male, age 74, left hemisphere 206.1
2219 Male, age 76, both hemispheres 195.6
1870 Female, age 42, unknown 181.6
1827 Male, age 72, unknown 175.3
1833 Male, age 53, unknown 172.6
2019 Male, age 18, unknown 163.8
1830 Male, age 51, unknown 158.8
2586 Male, age 75, left hemisphere 155.0
2828 Female, age 72, unknown 151.0
Dorsal raphe nucleus
nTPM: 165.3
2750 Male, age 76, both hemispheres 226.1
2298 Female, age 72, unknown 170.3
2047 Male, age 72, unknown 164.1
1828 Male, age 53, unknown 146.0
2016 Female, age 72, unknown 120.0
Inferior colliculus
nTPM: 140.3
2097 Female, age 72, unknown 155.2
1848 Female, age 42, unknown 138.4
1890 Male, age 53, unknown 134.3
2849 Male, age 72, unknown 133.3
Median raphe nucleus
nTPM: 209.9
2220 Male, age 76, midline 209.9
Periaquaductal grey, anterior
nTPM: 157.0
1947 Male, age 18, unknown 177.6
1795 Male, age 51, unknown 150.4
2502 Female, age 75, unknown 142.9
Periaquaductal grey, dorsal
nTPM: 126.5
2464 Female, age 72, unknown 138.9
1831 Male, age 72, unknown 130.0
1840 Male, age 53, unknown 126.0
2850 Male, age 76, both hemispheres 111.1
Periaquaductal grey, lateral
nTPM: 115.0
2053 Male, age 18, unknown 136.5
2272 Male, age 74, both hemispheres 111.1
2140 Male, age 76, both hemispheres 97.5
Pretectal area
nTPM: 161.6
2007 Male, age 72, unknown 210.1
1815 Male, age 53, unknown 206.1
1816 Male, age 51, unknown 206.0
1944 Female, age 72, unknown 198.2
1817 Female, age 42, unknown 197.0
2224 Female, age 72, unknown 155.3
2825 Male, age 18, unknown 141.3
2667 Female, age 75, unknown 129.3
2316 Male, age 76, right hemisphere 125.3
2407 Male, age 75, both hemispheres 117.8
2273 Male, age 74, both hemispheres 91.7
Red nucleus
nTPM: 177.4
2725 Female, age 75, unknown 220.7
1821 Female, age 72, unknown 206.3
2588 Male, age 74, left hemisphere 202.1
2503 Female, age 72, unknown 190.0
1904 Male, age 53, unknown 176.6
1865 Male, age 51, unknown 173.4
2823 Male, age 76, right hemisphere 171.6
2584 Male, age 75, left hemisphere 170.1
2785 Male, age 18, unknown 163.8
1954 Female, age 42, unknown 157.3
2769 Male, age 72, unknown 149.8
2227 Male, age 72, unknown 147.3
Substantia nigra
nTPM: 232.8
1916 Female, age 42, unknown 328.1
2241 Male, age 72, unknown 282.5
1851 Male, age 51, unknown 279.4
2409 Female, age 72, unknown 255.6
1941 Male, age 53, unknown 250.0
1889 Female, age 72, unknown 225.8
2699 Male, age 18, unknown 205.3
2583 Male, age 75, right hemisphere 180.9
2665 Male, age 74, both hemispheres 167.5
2590 Female, age 75, unknown 153.2
Superior colliculus
nTPM: 161.7
2668 Female, age 75, unknown 244.4
1895 Male, age 76, right hemisphere 176.2
1796 Male, age 53, unknown 174.5
2587 Male, age 74, left hemisphere 169.4
2087 Female, age 72, unknown 167.6
2261 Male, age 18, unknown 163.0
1913 Female, age 42, unknown 161.0
1839 Male, age 51, unknown 143.1
1995 Male, age 72, unknown 132.9
2664 Male, age 75, both hemispheres 85.2
Ventral tegmental area
nTPM: 214.0
2410 Female, age 72, unknown 290.2
2218 Male, age 76, both hemispheres 259.9
1915 Female, age 42, unknown 229.0
2223 Female, age 72, unknown 188.8
1942 Male, age 51, unknown 164.7
2021 Male, age 53, unknown 151.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

52.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 52.7
Samples: 139

Max nTPM: 155.7
Min nTPM: 12.7
Std nTPM: 28.8
Median nTPM: 45.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 155.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 142.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 141.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 117.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 114.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 113.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 110.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 107.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 106.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 102.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 101.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 101.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 98.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 90.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 90.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 89.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 88.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 88.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 87.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 85.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 82.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 81.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 81.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 78.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 78.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 76.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 76.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 75.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 74.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 73.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 72.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 71.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 71.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 71.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 70.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 70.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 69.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 67.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 65.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 65.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 61.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 61.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 61.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 61.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 60.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 60.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 59.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 58.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 58.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 57.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 57.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 56.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 56.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 55.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 54.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 53.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 53.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 52.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 51.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 51.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 50.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 49.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 49.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 49.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 47.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 47.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 46.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 45.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 45.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 45.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 44.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 44.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 43.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 43.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 42.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 41.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 41.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 41.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 40.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 39.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 39.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 39.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 39.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 38.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 38.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 38.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 38.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 38.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 37.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 37.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 37.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 36.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 36.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 36.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 35.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 34.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 34.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 34.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 32.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 32.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 32.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 32.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 32.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 31.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 31.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 30.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 29.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 29.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 29.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 28.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 28.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 28.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 28.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 28.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 27.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 27.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 25.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 24.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 24.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 24.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 23.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 22.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 21.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 21.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 21.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 21.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 20.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 19.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 19.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 19.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 19.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 19.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 19.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 18.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 18.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 17.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 15.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 14.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 12.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

305.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 305.2
FF:10158-103A5 76 years, female 305.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

233.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 228.1
Samples: 4

Max nTPM: 328.3
Min nTPM: 147.6
Sample A Female 284.8
Sample B Female 151.7
Sample C Male 328.3
Sample D Male 147.6
Midbrain
nTPM: 233.2
Samples: 4

Max nTPM: 338.1
Min nTPM: 184.7
Sample A Female 211.2
Sample B Female 184.7
Sample C Male 338.1
Sample D Male 198.7
Periaqueductal gray
nTPM: 143.8
Samples: 3

Max nTPM: 166.0
Min nTPM: 123.2
Sample B Female 142.2
Sample C Male 166.0
Sample D Male 123.2
Superior colliculi
nTPM: 208.0
Samples: 4

Max nTPM: 303.2
Min nTPM: 119.4
Sample A Female 188.8
Sample B Female 119.4
Sample C Male 303.2
Sample D Male 220.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

155.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 155.1
Samples: 4

Max nTPM: 159.6
Min nTPM: 148.1
Sample A Male 148.1
Sample B Male 159.6
Sample C Female 158.2
Sample D Female 154.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

14.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 14.2
71358627 Antisense, RP_050725_03_F05, Mouse strain C57BL/6J (56 days, male) 15.3
68844642 Antisense, RP_050222_02_B03, Mouse strain C57BL/6J (56 days, male) 13.2

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