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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:131.1 nTPM
HPA Brain:318.7 nTPM
GTEx:131.1 nTPM
FANTOM5:408.6 Scaled Tags Per Million
Pig:350.3 nTPM
Mouse:26.8 nTPM
Allen mouse:1.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

318.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 252.1
1870 Female, age 42, unknown 319.3
1830 Male, age 51, unknown 303.7
2411 Female, age 72, unknown 288.6
2666 Male, age 74, left hemisphere 281.5
2828 Female, age 72, unknown 278.1
2019 Male, age 18, unknown 277.9
1833 Male, age 53, unknown 260.7
2586 Male, age 75, left hemisphere 205.2
1827 Male, age 72, unknown 175.6
2219 Male, age 76, both hemispheres 130.7
Dorsal raphe nucleus
nTPM: 231.4
2750 Male, age 76, both hemispheres 252.7
1828 Male, age 53, unknown 247.1
2016 Female, age 72, unknown 242.5
2047 Male, age 72, unknown 209.9
2298 Female, age 72, unknown 204.9
Inferior colliculus
nTPM: 212.3
1890 Male, age 53, unknown 247.2
2097 Female, age 72, unknown 238.1
1848 Female, age 42, unknown 190.5
2849 Male, age 72, unknown 173.4
Median raphe nucleus
nTPM: 182.0
2220 Male, age 76, midline 182.0
Periaquaductal grey, anterior
nTPM: 147.7
2502 Female, age 75, unknown 153.2
1947 Male, age 18, unknown 147.1
1795 Male, age 51, unknown 142.9
Periaquaductal grey, dorsal
nTPM: 183.8
2464 Female, age 72, unknown 219.2
1831 Male, age 72, unknown 199.5
2850 Male, age 76, both hemispheres 181.9
1840 Male, age 53, unknown 134.8
Periaquaductal grey, lateral
nTPM: 202.7
2053 Male, age 18, unknown 229.9
2140 Male, age 76, both hemispheres 192.9
2272 Male, age 74, both hemispheres 185.2
Pretectal area
nTPM: 164.1
2316 Male, age 76, right hemisphere 207.8
1815 Male, age 53, unknown 196.7
2825 Male, age 18, unknown 182.3
2273 Male, age 74, both hemispheres 174.3
2667 Female, age 75, unknown 169.1
1817 Female, age 42, unknown 168.3
2407 Male, age 75, both hemispheres 166.6
1944 Female, age 72, unknown 156.6
2007 Male, age 72, unknown 143.7
2224 Female, age 72, unknown 139.1
1816 Male, age 51, unknown 100.9
Red nucleus
nTPM: 318.7
1865 Male, age 51, unknown 400.5
2769 Male, age 72, unknown 366.6
2227 Male, age 72, unknown 363.7
2503 Female, age 72, unknown 341.7
1904 Male, age 53, unknown 333.7
1821 Female, age 72, unknown 333.6
1954 Female, age 42, unknown 331.6
2823 Male, age 76, right hemisphere 314.8
2785 Male, age 18, unknown 290.8
2725 Female, age 75, unknown 281.1
2588 Male, age 74, left hemisphere 240.5
2584 Male, age 75, left hemisphere 226.0
Substantia nigra
nTPM: 243.0
2583 Male, age 75, right hemisphere 296.1
2699 Male, age 18, unknown 275.2
1851 Male, age 51, unknown 266.2
2590 Female, age 75, unknown 248.9
2409 Female, age 72, unknown 247.0
1941 Male, age 53, unknown 239.5
2241 Male, age 72, unknown 224.1
1916 Female, age 42, unknown 211.6
2665 Male, age 74, both hemispheres 211.0
1889 Female, age 72, unknown 210.1
Superior colliculus
nTPM: 207.0
1913 Female, age 42, unknown 343.3
1995 Male, age 72, unknown 298.2
2587 Male, age 74, left hemisphere 244.8
2668 Female, age 75, unknown 198.0
1839 Male, age 51, unknown 197.1
1796 Male, age 53, unknown 178.5
2087 Female, age 72, unknown 166.9
2664 Male, age 75, both hemispheres 161.0
1895 Male, age 76, right hemisphere 153.5
2261 Male, age 18, unknown 128.8
Ventral tegmental area
nTPM: 270.5
2223 Female, age 72, unknown 395.3
2410 Female, age 72, unknown 297.1
1942 Male, age 51, unknown 251.0
1915 Female, age 42, unknown 236.4
2021 Male, age 53, unknown 227.8
2218 Male, age 76, both hemispheres 215.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

131.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 131.1
Samples: 139

Max nTPM: 339.8
Min nTPM: 33.1
Std nTPM: 49.2
Median nTPM: 129.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 339.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 258.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 235.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 235.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 228.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 228.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 225.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 219.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 215.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 210.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 203.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 199.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 198.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 193.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 192.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 192.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 189.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 187.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 186.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 185.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 183.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 179.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 176.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 176.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 176.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 173.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 173.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 172.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 168.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 163.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 161.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 159.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 158.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 158.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 155.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 152.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 151.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 151.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 150.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 149.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 149.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 147.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 147.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 146.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 144.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 144.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 143.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 143.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 142.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 142.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 141.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 141.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 140.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 139.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 137.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 136.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 136.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 135.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 134.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 134.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 133.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 133.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 132.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 132.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 132.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 131.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 131.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 131.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 130.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 129.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 129.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 126.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 125.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 124.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 123.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 120.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 119.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 119.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 119.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 119.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 119.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 119.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 118.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 118.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 118.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 118.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 118.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 117.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 116.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 116.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 115.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 114.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 114.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 111.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 109.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 108.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 104.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 103.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 103.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 103.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 101.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 100.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 99.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 96.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 96.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 96.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 93.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 93.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 93.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 92.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 92.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 90.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 90.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 89.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 89.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 87.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 86.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 81.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 79.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 73.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 72.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 72.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 71.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 71.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 70.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 69.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 68.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 65.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 65.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 63.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 61.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 57.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 56.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 52.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 50.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 48.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 43.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 39.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 33.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

408.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 408.6
FF:10158-103A5 76 years, female 408.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

350.3
Pig sample Sample description nTPM
Substantia nigra
nTPM: 331.9
Samples: 4

Max nTPM: 434.3
Min nTPM: 209.1
Sample A Female 356.9
Sample B Female 209.1
Sample C Male 327.1
Sample D Male 434.3
Midbrain
nTPM: 350.3
Samples: 4

Max nTPM: 701.8
Min nTPM: 182.1
Sample A Female 701.8
Sample B Female 278.5
Sample C Male 238.9
Sample D Male 182.1
Periaqueductal gray
nTPM: 247.9
Samples: 3

Max nTPM: 261.1
Min nTPM: 238.9
Sample B Female 261.1
Sample C Male 238.9
Sample D Male 243.6
Superior colliculi
nTPM: 254.4
Samples: 4

Max nTPM: 324.9
Min nTPM: 119.3
Sample A Female 273.5
Sample B Female 119.3
Sample C Male 299.9
Sample D Male 324.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

26.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 26.8
Samples: 4

Max nTPM: 31.0
Min nTPM: 24.1
Sample A Male 25.6
Sample B Male 24.1
Sample C Female 26.3
Sample D Female 31.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

1.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.7
69013438 Antisense, RP_050309_02_D07, Mouse strain C57BL/6J (56 days, male) 1.7

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