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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:173.7 nTPM
HPA Brain:359.6 nTPM
GTEx:173.7 nTPM
FANTOM5:199.7 Scaled Tags Per Million
Pig:387.3 nTPM
Mouse:160.8 nTPM
Allen mouse:7.2 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

359.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 293.4
2586 Male, age 75, left hemisphere 355.5
2666 Male, age 74, left hemisphere 347.2
2219 Male, age 76, both hemispheres 330.2
1827 Male, age 72, unknown 321.9
2019 Male, age 18, unknown 307.7
2828 Female, age 72, unknown 275.9
1830 Male, age 51, unknown 259.4
1833 Male, age 53, unknown 252.0
1870 Female, age 42, unknown 244.3
2411 Female, age 72, unknown 240.1
Dorsal raphe nucleus
nTPM: 239.5
1828 Male, age 53, unknown 255.7
2750 Male, age 76, both hemispheres 252.8
2016 Female, age 72, unknown 233.8
2047 Male, age 72, unknown 228.2
2298 Female, age 72, unknown 227.1
Inferior colliculus
nTPM: 313.1
2097 Female, age 72, unknown 358.5
1890 Male, age 53, unknown 356.2
1848 Female, age 42, unknown 283.6
2849 Male, age 72, unknown 254.3
Median raphe nucleus
nTPM: 260.0
2220 Male, age 76, midline 260.0
Periaquaductal grey, anterior
nTPM: 359.6
1947 Male, age 18, unknown 410.9
2502 Female, age 75, unknown 376.4
1795 Male, age 51, unknown 291.4
Periaquaductal grey, dorsal
nTPM: 221.5
1831 Male, age 72, unknown 232.7
2464 Female, age 72, unknown 230.9
2850 Male, age 76, both hemispheres 224.0
1840 Male, age 53, unknown 198.4
Periaquaductal grey, lateral
nTPM: 241.6
2272 Male, age 74, both hemispheres 261.8
2053 Male, age 18, unknown 249.5
2140 Male, age 76, both hemispheres 213.6
Pretectal area
nTPM: 292.5
2007 Male, age 72, unknown 376.0
1816 Male, age 51, unknown 373.1
1817 Female, age 42, unknown 372.5
1815 Male, age 53, unknown 344.5
1944 Female, age 72, unknown 318.2
2407 Male, age 75, both hemispheres 285.7
2667 Female, age 75, unknown 241.0
2825 Male, age 18, unknown 237.6
2316 Male, age 76, right hemisphere 237.5
2273 Male, age 74, both hemispheres 227.9
2224 Female, age 72, unknown 203.7
Red nucleus
nTPM: 315.9
2584 Male, age 75, left hemisphere 356.9
1821 Female, age 72, unknown 349.9
2503 Female, age 72, unknown 347.5
1865 Male, age 51, unknown 329.7
2785 Male, age 18, unknown 318.1
2725 Female, age 75, unknown 312.6
2227 Male, age 72, unknown 303.5
1954 Female, age 42, unknown 301.7
2769 Male, age 72, unknown 298.1
2588 Male, age 74, left hemisphere 294.1
1904 Male, age 53, unknown 290.9
2823 Male, age 76, right hemisphere 287.4
Substantia nigra
nTPM: 318.8
1941 Male, age 53, unknown 363.5
1916 Female, age 42, unknown 347.4
1851 Male, age 51, unknown 335.8
1889 Female, age 72, unknown 331.0
2665 Male, age 74, both hemispheres 326.1
2241 Male, age 72, unknown 309.0
2590 Female, age 75, unknown 306.2
2583 Male, age 75, right hemisphere 300.8
2409 Female, age 72, unknown 288.5
2699 Male, age 18, unknown 280.2
Superior colliculus
nTPM: 294.6
2668 Female, age 75, unknown 344.1
2664 Male, age 75, both hemispheres 331.4
2261 Male, age 18, unknown 312.6
2087 Female, age 72, unknown 298.5
1796 Male, age 53, unknown 294.2
1913 Female, age 42, unknown 279.0
1995 Male, age 72, unknown 275.4
1895 Male, age 76, right hemisphere 271.1
2587 Male, age 74, left hemisphere 270.9
1839 Male, age 51, unknown 268.9
Ventral tegmental area
nTPM: 261.7
2410 Female, age 72, unknown 281.5
1915 Female, age 42, unknown 280.5
2218 Male, age 76, both hemispheres 272.1
1942 Male, age 51, unknown 269.3
2223 Female, age 72, unknown 253.4
2021 Male, age 53, unknown 213.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

173.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 173.7
Samples: 139

Max nTPM: 303.3
Min nTPM: 95.6
Std nTPM: 45.4
Median nTPM: 163.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 303.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 297.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 293.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 283.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 282.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 268.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 262.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 259.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 255.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 248.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 247.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 240.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 240.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 239.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 237.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 234.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 234.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 233.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 231.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 228.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 226.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 220.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 220.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 214.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 214.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 212.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 211.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 209.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 208.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 208.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 207.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 206.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 205.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 204.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 201.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 200.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 196.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 195.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 195.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 194.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 193.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 191.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 189.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 188.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 188.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 187.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 186.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 185.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 185.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 184.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 183.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 182.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 182.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 179.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 179.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 178.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 174.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 174.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 173.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 173.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 172.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 171.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 171.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 170.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 170.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 167.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 167.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 165.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 165.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 163.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 163.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 163.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 162.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 161.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 161.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 160.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 159.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 158.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 156.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 155.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 155.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 155.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 154.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 154.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 154.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 154.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 153.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 153.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 153.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 153.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 153.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 152.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 152.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 151.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 151.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 149.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 147.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 147.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 147.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 147.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 146.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 145.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 144.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 143.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 142.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 141.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 140.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 139.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 137.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 136.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 136.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 135.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 134.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 134.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 133.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 133.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 131.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 131.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 130.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 130.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 127.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 125.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 123.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 121.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 119.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 118.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 118.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 115.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 114.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 113.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 111.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 109.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 105.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 105.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 101.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 100.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 97.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 97.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 95.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

199.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 199.7
FF:10158-103A5 76 years, female 199.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

387.3
Pig sample Sample description nTPM
Substantia nigra
nTPM: 345.1
Samples: 4

Max nTPM: 403.8
Min nTPM: 266.9
Sample A Female 403.8
Sample B Female 266.9
Sample C Male 338.9
Sample D Male 370.8
Midbrain
nTPM: 387.3
Samples: 4

Max nTPM: 444.9
Min nTPM: 365.2
Sample A Female 444.9
Sample B Female 366.6
Sample C Male 372.5
Sample D Male 365.2
Periaqueductal gray
nTPM: 282.1
Samples: 3

Max nTPM: 297.6
Min nTPM: 269.8
Sample B Female 297.6
Sample C Male 279.0
Sample D Male 269.8
Superior colliculi
nTPM: 374.3
Samples: 4

Max nTPM: 423.2
Min nTPM: 248.6
Sample A Female 423.2
Sample B Female 248.6
Sample C Male 412.7
Sample D Male 412.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

160.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 160.8
Samples: 4

Max nTPM: 163.5
Min nTPM: 156.9
Sample A Male 161.3
Sample B Male 161.3
Sample C Female 163.5
Sample D Female 156.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

7.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 7.2
70445658 Antisense, RP_050614_04_C09, Mouse strain C57BL/6J (56 days, male) 7.8
74988529 Antisense, RP_060315_05_E08, Mouse strain C57BL/6J (56 days, male) 6.6

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