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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:355.9 nTPM
HPA Brain:45.3 nTPM
GTEx:355.9 nTPM
FANTOM5:1064.0 Scaled Tags Per Million
Pig:224.5 nTPM
Mouse:350.0 nTPM
Allen mouse:0.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

45.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 37.0
1870 Female, age 42, unknown 48.0
1833 Male, age 53, unknown 44.1
1830 Male, age 51, unknown 41.9
2411 Female, age 72, unknown 41.3
2219 Male, age 76, both hemispheres 40.7
2019 Male, age 18, unknown 39.0
1827 Male, age 72, unknown 35.9
2828 Female, age 72, unknown 30.7
2666 Male, age 74, left hemisphere 30.3
2586 Male, age 75, left hemisphere 17.7
Dorsal raphe nucleus
nTPM: 34.9
2750 Male, age 76, both hemispheres 47.9
1828 Male, age 53, unknown 36.5
2016 Female, age 72, unknown 31.6
2047 Male, age 72, unknown 29.3
2298 Female, age 72, unknown 29.0
Inferior colliculus
nTPM: 40.6
2849 Male, age 72, unknown 44.8
1848 Female, age 42, unknown 40.6
1890 Male, age 53, unknown 38.6
2097 Female, age 72, unknown 38.2
Median raphe nucleus
nTPM: 45.3
2220 Male, age 76, midline 45.3
Periaquaductal grey, anterior
nTPM: 34.8
2502 Female, age 75, unknown 38.1
1947 Male, age 18, unknown 35.4
1795 Male, age 51, unknown 30.7
Periaquaductal grey, dorsal
nTPM: 41.9
2850 Male, age 76, both hemispheres 55.1
2464 Female, age 72, unknown 40.7
1831 Male, age 72, unknown 39.1
1840 Male, age 53, unknown 32.8
Periaquaductal grey, lateral
nTPM: 37.0
2140 Male, age 76, both hemispheres 44.5
2272 Male, age 74, both hemispheres 37.7
2053 Male, age 18, unknown 28.8
Pretectal area
nTPM: 39.9
2667 Female, age 75, unknown 50.4
1815 Male, age 53, unknown 44.4
2316 Male, age 76, right hemisphere 43.4
2825 Male, age 18, unknown 41.5
1816 Male, age 51, unknown 39.5
2007 Male, age 72, unknown 39.3
1817 Female, age 42, unknown 39.0
2224 Female, age 72, unknown 39.0
1944 Female, age 72, unknown 38.6
2273 Male, age 74, both hemispheres 36.7
2407 Male, age 75, both hemispheres 26.7
Red nucleus
nTPM: 44.3
2823 Male, age 76, right hemisphere 59.9
2503 Female, age 72, unknown 52.2
1954 Female, age 42, unknown 50.2
1904 Male, age 53, unknown 49.2
1865 Male, age 51, unknown 49.0
1821 Female, age 72, unknown 48.4
2725 Female, age 75, unknown 45.3
2785 Male, age 18, unknown 41.1
2769 Male, age 72, unknown 39.9
2227 Male, age 72, unknown 39.8
2588 Male, age 74, left hemisphere 31.3
2584 Male, age 75, left hemisphere 25.0
Substantia nigra
nTPM: 36.5
2699 Male, age 18, unknown 46.7
2241 Male, age 72, unknown 43.3
2409 Female, age 72, unknown 39.8
1889 Female, age 72, unknown 39.7
1941 Male, age 53, unknown 37.2
2665 Male, age 74, both hemispheres 37.0
1851 Male, age 51, unknown 33.6
1916 Female, age 42, unknown 33.3
2583 Male, age 75, right hemisphere 27.1
2590 Female, age 75, unknown 27.1
Superior colliculus
nTPM: 38.6
1913 Female, age 42, unknown 53.4
1895 Male, age 76, right hemisphere 49.6
2587 Male, age 74, left hemisphere 41.6
1995 Male, age 72, unknown 41.3
2087 Female, age 72, unknown 38.6
1839 Male, age 51, unknown 37.0
2668 Female, age 75, unknown 34.1
2261 Male, age 18, unknown 33.1
1796 Male, age 53, unknown 30.5
2664 Male, age 75, both hemispheres 27.0
Ventral tegmental area
nTPM: 37.0
2223 Female, age 72, unknown 42.9
2218 Male, age 76, both hemispheres 38.6
2410 Female, age 72, unknown 37.4
2021 Male, age 53, unknown 34.6
1942 Male, age 51, unknown 34.3
1915 Female, age 42, unknown 34.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

355.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 355.9
Samples: 139

Max nTPM: 721.0
Min nTPM: 232.6
Std nTPM: 77.2
Median nTPM: 344.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 721.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 578.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 573.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 560.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 536.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 528.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 524.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 511.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 496.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 484.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 478.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 474.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 471.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 463.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 459.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 450.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 444.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 444.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 435.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 435.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 428.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 426.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 420.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 418.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 417.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 413.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 409.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 404.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 399.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 393.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 393.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 393.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 392.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 388.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 387.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 387.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 386.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 378.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 378.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 377.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 375.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 375.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 372.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 371.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 365.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 363.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 362.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 362.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 361.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 361.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 360.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 355.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 355.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 352.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 352.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 351.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 351.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 351.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 351.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 350.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 350.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 349.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 348.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 348.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 348.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 346.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 345.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 345.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 345.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 344.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 343.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 337.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 335.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 334.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 334.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 334.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 333.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 332.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 331.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 330.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 330.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 329.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 329.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 329.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 327.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 326.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 320.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 318.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 318.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 318.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 316.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 315.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 311.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 311.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 310.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 309.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 308.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 308.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 307.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 307.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 306.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 306.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 305.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 304.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 303.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 302.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 302.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 301.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 298.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 298.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 297.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 297.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 297.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 293.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 293.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 293.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 289.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 288.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 288.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 286.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 284.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 283.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 283.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 282.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 281.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 278.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 277.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 277.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 272.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 266.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 260.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 259.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 259.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 258.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 254.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 253.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 250.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 249.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 232.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

1064.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 1064.0
FF:10158-103A5 76 years, female 1064.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

224.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 201.5
Samples: 4

Max nTPM: 237.6
Min nTPM: 183.6
Sample A Female 183.6
Sample B Female 191.8
Sample C Male 193.1
Sample D Male 237.6
Midbrain
nTPM: 215.3
Samples: 4

Max nTPM: 276.0
Min nTPM: 175.6
Sample A Female 276.0
Sample B Female 223.4
Sample C Male 186.2
Sample D Male 175.6
Periaqueductal gray
nTPM: 224.5
Samples: 3

Max nTPM: 229.1
Min nTPM: 219.9
Sample B Female 229.1
Sample C Male 219.9
Sample D Male 224.5
Superior colliculi
nTPM: 190.8
Samples: 4

Max nTPM: 211.9
Min nTPM: 168.8
Sample A Female 187.2
Sample B Female 168.8
Sample C Male 195.3
Sample D Male 211.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

350.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 350.1
Samples: 4

Max nTPM: 366.2
Min nTPM: 340.1
Sample A Male 341.5
Sample B Male 352.4
Sample C Female 366.2
Sample D Female 340.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.0
71232819 Antisense, RP_050503_02_A04, Mouse strain C57BL/6J (56 days, male) 0.0

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