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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:196.3 nTPM
HPA Brain:229.3 nTPM
GTEx:196.3 nTPM
FANTOM5:282.6 Scaled Tags Per Million
Pig:197.7 nTPM
Mouse:7.5 nTPM
Allen mouse:0.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

229.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 166.6
1830 Male, age 51, unknown 204.2
2666 Male, age 74, left hemisphere 201.2
1833 Male, age 53, unknown 189.9
2586 Male, age 75, left hemisphere 189.2
2019 Male, age 18, unknown 183.6
1870 Female, age 42, unknown 179.2
2411 Female, age 72, unknown 164.9
2828 Female, age 72, unknown 148.2
1827 Male, age 72, unknown 105.9
2219 Male, age 76, both hemispheres 99.3
Dorsal raphe nucleus
nTPM: 112.6
2750 Male, age 76, both hemispheres 201.8
1828 Male, age 53, unknown 115.9
2016 Female, age 72, unknown 109.0
2047 Male, age 72, unknown 79.5
2298 Female, age 72, unknown 56.9
Inferior colliculus
nTPM: 109.1
1890 Male, age 53, unknown 124.1
1848 Female, age 42, unknown 108.6
2849 Male, age 72, unknown 106.1
2097 Female, age 72, unknown 97.7
Median raphe nucleus
nTPM: 91.8
2220 Male, age 76, midline 91.8
Periaquaductal grey, anterior
nTPM: 90.4
2502 Female, age 75, unknown 107.4
1947 Male, age 18, unknown 93.2
1795 Male, age 51, unknown 70.5
Periaquaductal grey, dorsal
nTPM: 71.3
2464 Female, age 72, unknown 110.9
1831 Male, age 72, unknown 86.9
1840 Male, age 53, unknown 44.9
2850 Male, age 76, both hemispheres 42.5
Periaquaductal grey, lateral
nTPM: 65.8
2053 Male, age 18, unknown 90.1
2272 Male, age 74, both hemispheres 65.3
2140 Male, age 76, both hemispheres 41.9
Pretectal area
nTPM: 92.0
1815 Male, age 53, unknown 144.6
1817 Female, age 42, unknown 127.3
2316 Male, age 76, right hemisphere 116.6
2007 Male, age 72, unknown 110.4
2407 Male, age 75, both hemispheres 108.9
2825 Male, age 18, unknown 96.4
1944 Female, age 72, unknown 69.7
1816 Male, age 51, unknown 63.9
2667 Female, age 75, unknown 62.6
2224 Female, age 72, unknown 60.1
2273 Male, age 74, both hemispheres 51.2
Red nucleus
nTPM: 229.3
2823 Male, age 76, right hemisphere 271.3
1865 Male, age 51, unknown 262.7
1821 Female, age 72, unknown 261.4
1904 Male, age 53, unknown 256.9
2588 Male, age 74, left hemisphere 250.7
2769 Male, age 72, unknown 234.0
2227 Male, age 72, unknown 225.8
2503 Female, age 72, unknown 223.2
1954 Female, age 42, unknown 215.9
2785 Male, age 18, unknown 195.3
2725 Female, age 75, unknown 181.3
2584 Male, age 75, left hemisphere 172.6
Substantia nigra
nTPM: 122.1
2665 Male, age 74, both hemispheres 144.7
1851 Male, age 51, unknown 139.7
2590 Female, age 75, unknown 136.3
2583 Male, age 75, right hemisphere 133.2
1889 Female, age 72, unknown 131.1
2409 Female, age 72, unknown 129.6
2699 Male, age 18, unknown 115.3
2241 Male, age 72, unknown 99.8
1916 Female, age 42, unknown 96.3
1941 Male, age 53, unknown 95.2
Superior colliculus
nTPM: 127.6
1995 Male, age 72, unknown 174.1
1913 Female, age 42, unknown 172.7
2668 Female, age 75, unknown 155.6
1895 Male, age 76, right hemisphere 149.2
2587 Male, age 74, left hemisphere 148.4
1839 Male, age 51, unknown 136.2
2664 Male, age 75, both hemispheres 94.1
1796 Male, age 53, unknown 90.0
2261 Male, age 18, unknown 78.8
2087 Female, age 72, unknown 77.4
Ventral tegmental area
nTPM: 119.7
2223 Female, age 72, unknown 155.1
2410 Female, age 72, unknown 148.7
1942 Male, age 51, unknown 106.8
1915 Female, age 42, unknown 106.6
2021 Male, age 53, unknown 103.7
2218 Male, age 76, both hemispheres 97.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

196.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 196.3
Samples: 139

Max nTPM: 454.0
Min nTPM: 56.9
Std nTPM: 91.3
Median nTPM: 175.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 454.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 447.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 438.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 398.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 395.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 386.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 386.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 382.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 379.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 375.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 374.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 369.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 356.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 347.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 342.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 319.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 316.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 316.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 308.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 304.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 301.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 299.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 294.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 293.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 274.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 272.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 269.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 268.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 267.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 266.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 264.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 259.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 253.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 253.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 246.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 243.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 243.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 231.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 229.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 228.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 227.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 225.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 223.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 213.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 212.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 210.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 206.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 206.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 204.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 204.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 202.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 200.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 199.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 197.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 196.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 196.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 196.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 195.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 194.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 191.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 190.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 190.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 189.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 184.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 182.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 181.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 180.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 179.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 177.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 175.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 174.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 171.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 171.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 171.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 169.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 169.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 168.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 168.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 168.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 168.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 167.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 166.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 163.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 159.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 158.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 158.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 154.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 153.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 150.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 148.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 147.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 146.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 145.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 141.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 141.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 140.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 138.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 138.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 138.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 136.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 131.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 127.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 126.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 125.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 124.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 122.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 121.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 120.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 119.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 118.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 116.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 115.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 115.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 114.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 114.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 113.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 111.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 109.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 109.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 108.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 107.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 106.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 106.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 103.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 102.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 101.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 97.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 87.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 83.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 82.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 82.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 81.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 80.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 75.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 74.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 69.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 60.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 59.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 56.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

282.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 282.6
FF:10158-103A5 76 years, female 282.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

197.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 178.8
Samples: 4

Max nTPM: 262.2
Min nTPM: 130.7
Sample A Female 173.8
Sample B Female 130.7
Sample C Male 148.3
Sample D Male 262.2
Midbrain
nTPM: 197.7
Samples: 4

Max nTPM: 404.7
Min nTPM: 100.5
Sample A Female 404.7
Sample B Female 179.5
Sample C Male 106.1
Sample D Male 100.5
Periaqueductal gray
nTPM: 116.1
Samples: 3

Max nTPM: 138.6
Min nTPM: 96.8
Sample B Female 138.6
Sample C Male 96.8
Sample D Male 112.9
Superior colliculi
nTPM: 150.3
Samples: 4

Max nTPM: 176.7
Min nTPM: 82.9
Sample A Female 174.7
Sample B Female 82.9
Sample C Male 166.7
Sample D Male 176.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

7.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 7.6
Samples: 4

Max nTPM: 8.8
Min nTPM: 6.7
Sample A Male 8.8
Sample B Male 7.8
Sample C Female 6.9
Sample D Female 6.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.1
67815543 Antisense, RP_040920_01_H02, Mouse strain C57BL/6J (56 days, male) 0.1

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