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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:206.2 nTPM
HPA Brain:290.4 nTPM
GTEx:206.2 nTPM
FANTOM5:447.9 Scaled Tags Per Million
Pig:176.5 nTPM
Mouse:2.9 nTPM
Allen mouse:0.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

290.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 195.2
1830 Male, age 51, unknown 277.6
2411 Female, age 72, unknown 257.1
2019 Male, age 18, unknown 251.7
1870 Female, age 42, unknown 239.4
1833 Male, age 53, unknown 233.4
2828 Female, age 72, unknown 184.7
2586 Male, age 75, left hemisphere 143.3
2666 Male, age 74, left hemisphere 135.7
1827 Male, age 72, unknown 116.4
2219 Male, age 76, both hemispheres 113.1
Dorsal raphe nucleus
nTPM: 145.2
2750 Male, age 76, both hemispheres 292.9
1828 Male, age 53, unknown 145.5
2016 Female, age 72, unknown 126.4
2047 Male, age 72, unknown 93.7
2298 Female, age 72, unknown 67.4
Inferior colliculus
nTPM: 119.2
1890 Male, age 53, unknown 149.6
1848 Female, age 42, unknown 124.9
2849 Male, age 72, unknown 111.6
2097 Female, age 72, unknown 90.7
Median raphe nucleus
nTPM: 139.3
2220 Male, age 76, midline 139.3
Periaquaductal grey, anterior
nTPM: 77.8
1947 Male, age 18, unknown 95.8
1795 Male, age 51, unknown 73.8
2502 Female, age 75, unknown 63.7
Periaquaductal grey, dorsal
nTPM: 72.4
2464 Female, age 72, unknown 125.9
1831 Male, age 72, unknown 87.6
2850 Male, age 76, both hemispheres 38.5
1840 Male, age 53, unknown 37.7
Periaquaductal grey, lateral
nTPM: 85.7
2272 Male, age 74, both hemispheres 128.7
2053 Male, age 18, unknown 91.5
2140 Male, age 76, both hemispheres 37.0
Pretectal area
nTPM: 101.4
2407 Male, age 75, both hemispheres 159.7
2316 Male, age 76, right hemisphere 152.1
1815 Male, age 53, unknown 123.2
2007 Male, age 72, unknown 117.9
2825 Male, age 18, unknown 112.4
2273 Male, age 74, both hemispheres 109.3
1817 Female, age 42, unknown 105.8
2224 Female, age 72, unknown 72.5
2667 Female, age 75, unknown 59.2
1944 Female, age 72, unknown 58.4
1816 Male, age 51, unknown 45.0
Red nucleus
nTPM: 290.4
1821 Female, age 72, unknown 353.0
1865 Male, age 51, unknown 347.9
2769 Male, age 72, unknown 340.0
2227 Male, age 72, unknown 337.0
2823 Male, age 76, right hemisphere 335.4
1904 Male, age 53, unknown 289.3
2785 Male, age 18, unknown 287.3
2503 Female, age 72, unknown 253.5
1954 Female, age 42, unknown 240.7
2584 Male, age 75, left hemisphere 236.4
2725 Female, age 75, unknown 235.8
2588 Male, age 74, left hemisphere 228.7
Substantia nigra
nTPM: 131.4
2583 Male, age 75, right hemisphere 187.7
2590 Female, age 75, unknown 183.6
1889 Female, age 72, unknown 159.2
1851 Male, age 51, unknown 150.9
2409 Female, age 72, unknown 143.4
1941 Male, age 53, unknown 115.0
1916 Female, age 42, unknown 106.8
2699 Male, age 18, unknown 106.6
2241 Male, age 72, unknown 95.1
2665 Male, age 74, both hemispheres 65.8
Superior colliculus
nTPM: 136.4
2668 Female, age 75, unknown 200.0
1913 Female, age 42, unknown 188.5
1895 Male, age 76, right hemisphere 186.7
2587 Male, age 74, left hemisphere 164.2
1995 Male, age 72, unknown 157.5
1839 Male, age 51, unknown 148.9
1796 Male, age 53, unknown 103.5
2664 Male, age 75, both hemispheres 79.0
2087 Female, age 72, unknown 74.9
2261 Male, age 18, unknown 60.6
Ventral tegmental area
nTPM: 191.3
2223 Female, age 72, unknown 399.1
2410 Female, age 72, unknown 185.7
2021 Male, age 53, unknown 160.6
1942 Male, age 51, unknown 145.8
2218 Male, age 76, both hemispheres 144.4
1915 Female, age 42, unknown 112.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

206.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 206.2
Samples: 139

Max nTPM: 968.2
Min nTPM: 40.3
Std nTPM: 141.8
Median nTPM: 156.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 968.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 768.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 653.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 580.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 526.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 523.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 493.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 480.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 453.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 432.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 432.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 396.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 382.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 382.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 375.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 372.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 355.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 348.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 331.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 317.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 310.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 296.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 289.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 289.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 288.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 288.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 284.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 283.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 276.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 275.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 271.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 268.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 264.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 261.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 258.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 253.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 246.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 244.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 242.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 242.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 240.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 240.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 238.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 236.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 221.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 215.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 215.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 214.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 211.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 210.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 210.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 208.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 206.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 205.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 201.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 200.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 195.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 195.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 191.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 188.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 187.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 186.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 184.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 183.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 180.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 172.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 170.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 165.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 162.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 156.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 156.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 156.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 154.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 149.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 149.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 147.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 146.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 146.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 145.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 145.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 145.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 143.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 143.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 141.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 140.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 140.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 138.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 138.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 138.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 137.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 137.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 136.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 134.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 130.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 130.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 129.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 128.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 126.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 125.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 124.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 120.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 120.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 120.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 119.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 118.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 117.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 117.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 116.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 116.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 110.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 108.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 107.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 105.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 104.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 100.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 99.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 98.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 97.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 91.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 90.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 89.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 87.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 82.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 80.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 80.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 74.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 72.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 71.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 65.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 64.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 63.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 63.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 62.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 61.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 58.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 57.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 46.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 43.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 40.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

447.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 447.9
FF:10158-103A5 76 years, female 447.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

176.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 144.9
Samples: 4

Max nTPM: 228.3
Min nTPM: 96.0
Sample A Female 136.7
Sample B Female 96.0
Sample C Male 118.6
Sample D Male 228.3
Midbrain
nTPM: 176.5
Samples: 4

Max nTPM: 387.1
Min nTPM: 76.6
Sample A Female 387.1
Sample B Female 163.6
Sample C Male 76.6
Sample D Male 78.6
Periaqueductal gray
nTPM: 97.3
Samples: 3

Max nTPM: 132.0
Min nTPM: 69.8
Sample B Female 132.0
Sample C Male 69.8
Sample D Male 90.2
Superior colliculi
nTPM: 114.4
Samples: 4

Max nTPM: 139.9
Min nTPM: 67.2
Sample A Female 119.3
Sample B Female 67.2
Sample C Male 131.0
Sample D Male 139.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

2.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 2.9
Samples: 4

Max nTPM: 3.4
Min nTPM: 1.8
Sample A Male 3.4
Sample B Male 3.2
Sample C Female 1.8
Sample D Female 3.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.1
71529905 Antisense, RP_050915_01_C04, Mouse strain C57BL/6J (56 days, male) 0.1

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