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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
Not detected
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
134.7
nTPM
HPA:
83.7
nTPM
GTEx:
134.7
nTPM
FANTOM5:
204.5
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA041542
Antibody CAB007811
Cholangiocytes
Not detected
Not detected
Hepatocytes
Not detected
Not detected
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
83.7
Female, age 60
Liver sample 21 nTPM: 101.1
Male, age 54
Liver sample 23 nTPM: 111.8
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 89.6
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 67.3
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 40
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 97.7
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 25.8
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 162.9
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 83.6
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 57.6
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
134.7
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 134.7
Samples: 226
Max nTPM: 462.2
Min nTPM: 1.4
Std nTPM: 79.1
Median nTPM: 128.1
GTEX-11ZUS-2526-SM-59872
30-39 years, male
462.2
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
369.7
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
349.8
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
334.3
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
312.8
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
310.9
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
307.2
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
301.9
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
294.4
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
284.9
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
280.8
GTEX-QESD-2026-SM-447BI
20-29 years, male
274.8
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
266.7
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
263.1
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
258.2
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
255.2
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
255.0
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
251.7
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
248.7
GTEX-13112-1426-SM-5EGH8
50-59 years, male
245.4
GTEX-YECK-1926-SM-4W21H
60-69 years, male
245.2
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
241.7
GTEX-14JG1-1626-SM-664NH
40-49 years, male
237.4
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
233.6
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
230.9
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
230.8
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
224.8
GTEX-14E7W-1526-SM-6871X
70-79 years, male
223.8
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
222.3
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
222.3
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
220.8
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
219.5
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
219.2
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
218.0
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
216.6
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
215.8
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
215.5
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
214.5
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
212.7
GTEX-144GL-1426-SM-79OMA
50-59 years, male
210.6
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
209.9
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
207.6
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
205.1
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
204.8
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
204.6
GTEX-P78B-1326-SM-3P611
40-49 years, female
203.6
GTEX-R53T-0326-SM-48FEC
50-59 years, female
200.9
GTEX-18A7A-1526-SM-72D69
50-59 years, female
198.8
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
196.7
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
194.5
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
190.4
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
189.7
GTEX-1B932-1426-SM-793AN
40-49 years, female
188.9
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
186.0
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
185.1
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
185.1
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
185.0
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
183.2
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
181.1
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
177.7
GTEX-RN64-1826-SM-48FDV
50-59 years, male
177.2
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
176.8
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
174.4
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
173.2
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
169.1
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
168.7
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
168.0
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
167.9
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
167.7
GTEX-18465-1626-SM-7LG6N
50-59 years, male
166.6
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
165.5
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
164.9
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
162.8
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
161.5
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
159.0
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
158.9
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
158.4
GTEX-RU72-1426-SM-46MUF
50-59 years, female
158.4
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
156.8
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
156.1
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
155.6
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
155.2
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
154.7
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
154.6
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
153.7
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
152.6
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
152.5
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
150.4
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
149.4
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
147.5
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
146.5
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
146.2
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
145.7
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
145.3
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
145.0
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
144.2
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
143.9
GTEX-14PHX-0526-SM-664NW
50-59 years, male
141.3
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
139.5
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
138.7
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
138.2
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
138.0
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
136.2
GTEX-S33H-1626-SM-4AD68
30-39 years, male
135.8
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
133.9
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
130.7
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
130.7
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
130.3
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
129.9
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
129.7
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
129.6
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
129.1
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
129.1
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
127.1
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
126.8
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
126.5
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
125.9
GTEX-1399T-0826-SM-5IFES
60-69 years, male
125.6
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
125.6
GTEX-1B933-1226-SM-731DW
50-59 years, female
122.2
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
121.8
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
121.7
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
121.7
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
121.5
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
116.8
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
113.8
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
113.3
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
113.0
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
112.7
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
111.9
GTEX-X261-1726-SM-4PQYT
50-59 years, male
111.5
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
109.4
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
108.4
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
108.3
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
107.9
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
107.3
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
106.8
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
105.6
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
104.7
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
104.0
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
103.9
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
102.6
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
102.5
GTEX-11GSP-0626-SM-5986T
60-69 years, female
101.9
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
100.5
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
100.1
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
100.0
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
99.6
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
97.0
GTEX-17HHE-0126-SM-79398
50-59 years, male
92.4
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
92.0
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
90.4
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
90.1
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
89.0
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
88.5
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
87.8
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
86.4
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
85.4
GTEX-18A66-2026-SM-7189C
60-69 years, male
84.7
GTEX-12696-0826-SM-5EGGE
60-69 years, male
84.5
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
83.7
GTEX-13113-1326-SM-5GCOI
60-69 years, female
83.5
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
83.4
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
82.9
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
81.4
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
81.0
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
80.7
GTEX-REY6-1226-SM-48FDR
60-69 years, male
79.9
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
79.6
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
79.5
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
79.1
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
78.9
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
78.8
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
77.8
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
77.5
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
76.2
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
74.8
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
71.8
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
68.3
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
67.8
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
67.7
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
67.0
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
66.3
GTEX-O5YV-0726-SM-EV798
60-69 years, female
64.6
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
63.7
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
63.5
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
63.1
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
61.9
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
54.1
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
52.0
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
50.3
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
47.2
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
45.5
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
44.5
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
44.4
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
44.0
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
36.4
GTEX-17F96-1226-SM-79OK2
70-79 years, male
36.2
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
36.1
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
35.9
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
32.8
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
32.4
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
32.4
GTEX-14XAO-0226-SM-68728
60-69 years, female
31.5
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
30.3
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
30.2
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
30.0
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
28.5
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
27.5
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
26.2
GTEX-Q734-0326-SM-48U15
40-49 years, female
25.2
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
24.7
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
23.3
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
21.5
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
20.9
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
20.1
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
17.6
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
17.4
GTEX-QEL4-1226-SM-447A4
50-59 years, male
17.2
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
14.0
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
13.3
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
13.1
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
10.3
GTEX-14PJO-1726-SM-68719
60-69 years, male
9.5
GTEX-S32W-1926-SM-4AD63
50-59 years, female
8.7
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
1.4
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
