CEREBRAL CORTEX - Expression summary
Protein expression
Cerebral cortexi
h
m
l
n
Endothelial cells: Low
Glial cells: Medium
Neuronal cells: High
Neuropil: Medium
RNA expressioni
Consensus:104.2 nTPM
HPA:88.1 nTPM
HPA Brain:88.1 nTPM
HPA PFC Brain:76.9 nTPM
GTEx:104.2 nTPM
FANTOM5:118.2 Scaled Tags Per Million
Pig:72.4 nTPM
Mouse:139.1 nTPM
Allen mouse:19.7 Expression energy

CEREBRAL CORTEX - Antibody stainingi
Antibody HPA008425
Endothelial cells Low
Glial cells Medium
Neuronal cells High
Neuropil Medium



CEREBRAL CORTEX - HPA RNA-seqi
Average nTPMi 88.1
N/A
Male, age 5
Cerebral cortex sample 48
nTPM: 86.5
overview
Female, age 40
Cerebral cortex sample 105
nTPM: 90.3
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65
overview
Male, age 70
Cerebral cortex sample 106
nTPM: 87.4
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65

CEREBRAL CORTEX - HPA Brain RNA-seq
Max subtype nTPMi 88.1
Sample id Sample description nTPM
Angular gyrus
nTPM: 77.2
2221 Female, age 67, right hemisphere 99.3
2103 Male, age 75, left hemisphere 98.6
1866 Male, age 76, both hemispheres 84.6
2260 Female, age 72, left hemisphere 83.8
1790 Male, age 76, right hemisphere 77.7
2602 Female, age 94, right hemisphere 66.5
2722 Male, age 61, left hemisphere 55.0
2265 Female, age 91, left hemisphere 52.2
Anterior cingulate cortex, supragenual-dorsal
nTPM: 70.0
1896 Female, age 85, right hemisphere 85.7
2547 Male, age 74, left hemisphere 76.0
2472 Male, age 75, left hemisphere 66.3
2478 Female, age 67, right hemisphere 66.1
2342 Female, age 94, right hemisphere 55.8
Anterior cingulate cortex, supragenual-ventral
nTPM: 66.7
1950 Female, age 85, right hemisphere 73.7
1755 Female, age 94, right hemisphere 68.2
2479 Female, age 67, right hemisphere 64.3
1761 Male, age 74, left hemisphere 64.2
2538 Male, age 75, left hemisphere 63.1
Anterior insular cortex, dorsal
nTPM: 63.4
2670 Male, age 75, left hemisphere 66.5
2506 Female, age 94, right hemisphere 65.4
2001 Male, age 76, right hemisphere 63.7
2235 Female, age 91, right hemisphere 58.0
Anterior insular cortex, ventral
nTPM: 76.1
1925 Female, age 91, left hemisphere 96.3
1852 Male, age 76, left hemisphere 79.2
2596 Male, age 75, left hemisphere 76.9
2262 Female, age 67, right hemisphere 71.4
2757 Male, age 61, right hemisphere 67.9
2507 Female, age 94, left hemisphere 64.6
Area parastriata, inferior
nTPM: 78.7
2234 Male, age 75, left hemisphere 107.1
2509 Female, age 94, left hemisphere 106.7
1789 Male, age 76, right hemisphere 82.9
2268 Male, age 61, right hemisphere 70.2
1758 Female, age 72, right hemisphere 68.0
1760 Female, age 67, left hemisphere 63.0
2421 Female, age 91, left hemisphere 52.8
Area parastriata, parietal
nTPM: 75.0
2420 Male, age 75, left hemisphere 88.0
1785 Male, age 76, right hemisphere 77.5
2680 Female, age 94, right hemisphere 74.3
2233 Male, age 61, right hemisphere 70.8
2236 Female, age 91, left hemisphere 64.4
Area parastriata, superior
nTPM: 88.1
2604 Female, age 94, right hemisphere 102.1
2435 Male, age 61, left hemisphere 96.1
2881 Male, age 76, left hemisphere 95.8
2419 Male, age 75, right hemisphere 85.6
1773 Female, age 91, left hemisphere 81.0
2684 Female, age 67, left hemisphere 67.8
Area parastriata, temporal
nTPM: 71.8
1804 Male, age 76, right hemisphere 76.6
2471 Male, age 75, left hemisphere 74.3
2424 Female, age 67, left hemisphere 72.6
2267 Male, age 61, right hemisphere 71.4
2681 Female, age 94, right hemisphere 64.0
Area striata
nTPM: 67.1
2679 Female, age 94, right hemisphere 73.5
1753 Female, age 72, right hemisphere 71.7
1884 Male, age 76, left hemisphere 71.0
2417 Male, age 61, right hemisphere 70.2
2002 Female, age 91, right hemisphere 59.8
2427 Female, age 91, left hemisphere 56.7
Claustrum
nTPM: 72.7
2198 Male, age 80, both hemispheres 86.6
2196 Female, age 79, unknown 85.1
1956 Male, age 74, unknown 81.5
2491 Male, age 75, both hemispheres 75.3
2392 Female, age 94, both hemispheres 72.3
2284 Female, age 91, both hemispheres 66.9
2292 Female, age 85, both hemispheres 65.1
2568 Male, age 61, both hemispheres 65.1
2645 Female, age 72, unknown 56.7
Frontal eye field
nTPM: 69.2
2147 Male, age 61, left hemisphere 77.6
2543 Male, age 74, left hemisphere 68.7
2441 Male, age 75, left hemisphere 65.8
2761 Female, age 94, left hemisphere 64.7
Frontal operculum
nTPM: 76.9
2030 Male, age 61, right hemisphere 95.6
2348 Male, age 75, left hemisphere 71.5
2781 Female, age 85, right hemisphere 63.7
Fusiform gyrus
nTPM: 78.0
2784 Female, age 85, left hemisphere 92.4
2431 Male, age 75, right hemisphere 84.4
1807 Male, age 76, left hemisphere 84.3
2074 Female, age 91, left hemisphere 81.0
2112 Male, age 80, both hemispheres 72.6
2433 Female, age 72, left hemisphere 69.4
2617 Female, age 94, left hemisphere 61.5
Inferior frontal gyrus, opercular
nTPM: 73.1
2866 Male, age 61, right hemisphere 89.0
2865 Male, age 61, left hemisphere 85.6
2873 Female, age 85, left hemisphere 83.5
2874 Female, age 85, right hemisphere 75.8
2868 Male, age 75, right hemisphere 71.3
2871 Female, age 94, left hemisphere 69.2
2875 Female, age 67, left hemisphere 67.9
2872 Female, age 94, right hemisphere 65.8
2867 Male, age 75, left hemisphere 64.8
2869 Male, age 74, left hemisphere 58.4
Inferior parietal lobule
nTPM: 73.2
2876 Male, age 76, right hemisphere 86.8
2418 Male, age 75, left hemisphere 75.6
2599 Female, age 94, left hemisphere 67.3
2606 Female, age 67, right hemisphere 63.0
Inferior temporal gyrus
nTPM: 75.4
1880 Male, age 80, right hemisphere 86.1
2430 Male, age 75, right hemisphere 83.4
1808 Male, age 76, left hemisphere 78.2
1965 Female, age 91, left hemisphere 75.7
1970 Female, age 85, right hemisphere 69.3
2689 Female, age 94, right hemisphere 59.8
Intraparietal deep sulcus
nTPM: 69.2
2600 Female, age 94, right hemisphere 78.0
2230 Male, age 61, right hemisphere 74.5
2798 Male, age 76, left hemisphere 71.2
2102 Female, age 91, left hemisphere 66.6
2607 Female, age 67, right hemisphere 65.3
2669 Male, age 75, left hemisphere 59.5
Lingual gyrus
nTPM: 71.6
1893 Male, age 76, left hemisphere 79.5
2838 Male, age 80, right hemisphere 78.7
2688 Male, age 75, right hemisphere 70.8
2073 Female, age 85, left hemisphere 65.2
2618 Female, age 94, left hemisphere 63.8
Middle cingulate cortex
nTPM: 67.6
2357 Female, age 67, right hemisphere 73.6
2640 Female, age 94, right hemisphere 73.4
2028 Female, age 85, left hemisphere 70.9
2539 Male, age 75, left hemisphere 61.9
2633 Male, age 74, left hemisphere 58.2
Middle temporal gyrus
nTPM: 74.4
1819 Male, age 80, right hemisphere 90.9
1799 Male, age 76, left hemisphere 76.7
2034 Female, age 91, right hemisphere 73.2
2616 Female, age 94, left hemisphere 68.7
2611 Male, age 75, right hemisphere 62.4
Occipital cortex
nTPM: 72.3
2426 Male, age 75, midline 82.6
1842 Male, age 76, right hemisphere 79.3
2677 Female, age 67, right hemisphere 67.6
2470 Male, age 75, right hemisphere 66.3
2608 Female, age 67, both hemispheres 65.9
Olfactory area
nTPM: 81.1
2756 Female, age 67, right hemisphere 96.2
1805 Female, age 85, right hemisphere 94.0
2222 Female, age 67, right hemisphere 91.1
2440 Male, age 75, left hemisphere 74.5
2542 Male, age 74, left hemisphere 65.5
2352 Female, age 94, right hemisphere 65.2
Olfactory tubercle
nTPM: 77.1
1846 Male, age 80, right hemisphere 92.8
1998 Female, age 91, both hemispheres 92.1
2856 Male, age 75, right hemisphere 62.3
2487 Female, age 94, left hemisphere 61.2
Orbitofrontal gyrus, anterior
nTPM: 68.7
2863 Female, age 85, right hemisphere 101.8
2864 Female, age 67, left hemisphere 62.6
2862 Female, age 85, left hemisphere 41.8
Paracentral lobule, anterior
nTPM: 79.0
1926 Male, age 61, left hemisphere 96.0
1776 Female, age 85, right hemisphere 81.8
2340 Female, age 67, right hemisphere 81.2
1754 Male, age 75, left hemisphere 79.4
2474 Male, age 74, left hemisphere 68.5
2638 Female, age 94, right hemisphere 66.9
Paracentral lobule, posterior
nTPM: 67.8
1775 Female, age 85, right hemisphere 86.7
2551 Female, age 94, right hemisphere 79.7
1764 Male, age 74, right hemisphere 64.7
2446 Male, age 75, left hemisphere 57.5
2345 Male, age 61, left hemisphere 50.2
Parietal operculum
nTPM: 65.0
2356 Female, age 67, right hemisphere 70.5
2719 Male, age 75, left hemisphere 66.1
2552 Female, age 94, right hemisphere 63.8
1763 Male, age 74, left hemisphere 59.6
Parieto-insular cortex
nTPM: 70.1
1976 Female, age 91, right hemisphere 107.3
2831 Male, age 76, right hemisphere 67.4
2671 Male, age 75, left hemisphere 61.5
2508 Female, age 94, right hemisphere 58.1
2232 Male, age 61, right hemisphere 56.3
Parieto-occipital transitional area
nTPM: 67.2
1784 Male, age 76, right hemisphere 78.5
2674 Female, age 94, right hemisphere 70.9
2468 Male, age 75, left hemisphere 66.9
2270 Male, age 61, right hemisphere 61.7
2683 Female, age 67, left hemisphere 57.8
Piriform cortex
nTPM: 78.5
2347 Male, age 75, right hemisphere 97.1
2153 Female, age 85, left hemisphere 60.0
Postcentral gyrus
nTPM: 87.9
2533 Male, age 75, right hemisphere 87.9
Postcentral gyrus, dorsal
nTPM: 84.7
1836 Female, age 85, right hemisphere 99.9
2339 Female, age 67, right hemisphere 93.4
2350 Male, age 75, left hemisphere 84.3
2477 Female, age 94, right hemisphere 83.8
2151 Male, age 61, left hemisphere 82.0
2544 Male, age 74, left hemisphere 64.8
Postcentral gyrus, middle
nTPM: 76.0
2146 Female, age 67, right hemisphere 88.5
1897 Female, age 85, right hemisphere 83.8
2248 Male, age 61, left hemisphere 81.1
2545 Male, age 74, left hemisphere 65.5
2444 Male, age 75, left hemisphere 61.0
Postcentral gyrus, ventral
nTPM: 71.0
2024 Female, age 85, right hemisphere 72.3
2836 Female, age 94, right hemisphere 71.4
2445 Male, age 75, left hemisphere 69.3
Posterior cingulate cortex
nTPM: 79.0
2553 Female, age 94, right hemisphere 88.9
1759 Male, age 74, right hemisphere 76.3
2473 Male, age 75, left hemisphere 71.7
Posterior cingulate cortex, dorsal
nTPM: 67.1
2641 Female, age 94, right hemisphere 79.3
2343 Male, age 61, left hemisphere 71.8
2556 Female, age 67, right hemisphere 68.2
2076 Female, age 85, right hemisphere 63.0
2634 Male, age 74, left hemisphere 60.5
2540 Male, age 75, right hemisphere 60.0
Posterior cingulate cortex, ventral
nTPM: 63.0
2541 Male, age 75, right hemisphere 72.0
1994 Female, age 85, right hemisphere 66.6
2448 Female, age 67, right hemisphere 66.3
1762 Female, age 94, right hemisphere 62.0
2635 Male, age 74, left hemisphere 56.7
2346 Male, age 61, left hemisphere 54.4
Posterior insular cortex
nTPM: 67.2
2832 Female, age 91, right hemisphere 85.3
1823 Male, age 76, right hemisphere 70.8
2511 Female, age 67, right hemisphere 69.0
2603 Female, age 94, left hemisphere 63.5
2597 Male, age 75, left hemisphere 59.3
2231 Male, age 61, left hemisphere 55.1
Precentral gyrus
nTPM: 69.2
2557 Male, age 75, right hemisphere 69.2
Precentral gyrus, dorsal
nTPM: 74.1
2476 Female, age 94, right hemisphere 82.4
1756 Male, age 74, left hemisphere 77.8
2442 Male, age 75, left hemisphere 70.0
2354 Female, age 67, right hemisphere 66.1
Precentral gyrus, middle
nTPM: 84.4
1969 Female, age 67, right hemisphere 116.4
1909 Male, age 61, left hemisphere 90.3
2443 Male, age 75, left hemisphere 77.6
2475 Male, age 74, right hemisphere 76.0
2549 Female, age 94, right hemisphere 61.6
Precentral gyrus, ventral
nTPM: 75.0
2662 Female, age 67, right hemisphere 96.4
2678 Male, age 74, left hemisphere 70.5
2550 Female, age 94, right hemisphere 68.0
2630 Male, age 75, left hemisphere 65.0
Precuneus
nTPM: 68.0
1782 Male, age 76, right hemisphere 81.8
2467 Male, age 75, right hemisphere 81.5
2673 Female, age 94, right hemisphere 71.6
2510 Female, age 67, right hemisphere 62.9
1780 Female, age 91, right hemisphere 60.1
2594 Male, age 61, left hemisphere 50.2
Premotor cortex, dorsal
nTPM: 77.0
1878 Female, age 85, right hemisphere 91.3
2027 Male, age 61, left hemisphere 87.7
2554 Female, age 67, right hemisphere 69.3
2631 Male, age 74, left hemisphere 68.5
2536 Male, age 75, left hemisphere 68.4
Premotor cortex, ventral
nTPM: 74.9
1777 Female, age 67, left hemisphere 109.6
1881 Female, age 85, right hemisphere 84.2
2349 Male, age 75, left hemisphere 72.3
1779 Male, age 61, left hemisphere 68.4
2637 Female, age 94, right hemisphere 60.9
1757 Male, age 74, left hemisphere 54.2
Retrosplenial cortex
nTPM: 79.9
1951 Male, age 61, right hemisphere 91.3
1914 Male, age 76, right hemisphere 80.5
2675 Female, age 94, left hemisphere 67.9
Subcentral gyrus, S2
nTPM: 67.8
2351 Male, age 75, left hemisphere 80.6
2072 Male, age 61, left hemisphere 71.5
2762 Male, age 74, left hemisphere 69.6
1964 Female, age 85, right hemisphere 67.6
2839 Female, age 94, right hemisphere 59.4
2555 Female, age 67, right hemisphere 58.5
Superior parietal lobule
nTPM: 74.4
1992 Female, age 91, right hemisphere 89.0
1800 Male, age 76, right hemisphere 87.0
2229 Male, age 61, right hemisphere 69.2
2605 Female, age 67, right hemisphere 65.9
2672 Female, age 94, right hemisphere 61.1
Superior temporal gyrus
nTPM: 74.8
1844 Female, age 91, left hemisphere 100.8
1843 Male, age 76, left hemisphere 75.3
2615 Female, age 94, left hemisphere 72.8
2687 Male, age 75, right hemisphere 62.7
2025 Male, age 80, right hemisphere 62.4
Supplementary motor cortex
nTPM: 70.8
1993 Male, age 61, left hemisphere 85.7
2548 Female, age 94, right hemisphere 67.6
2632 Male, age 74, left hemisphere 66.9
2537 Male, age 75, left hemisphere 63.0
Supramarginal gyrus
nTPM: 69.0
1991 Female, age 91, right hemisphere 76.2
1798 Male, age 76, right hemisphere 73.7
2415 Male, age 61, left hemisphere 68.9
2601 Female, age 94, left hemisphere 63.7
2513 Female, age 72, left hemisphere 62.5
Temporal pole
nTPM: 85.0
1832 Female, age 91, left hemisphere 113.5
1853 Female, age 85, right hemisphere 96.0
2518 Male, age 75, right hemisphere 82.8
1826 Male, age 76, right hemisphere 66.9
2612 Female, age 94, left hemisphere 65.8
Temporo-insular cortex, parainsular gyrus
nTPM: 59.9
1802 Male, age 76, left hemisphere 72.0
2598 Male, age 75, left hemisphere 70.7
2416 Male, age 61, right hemisphere 60.1
2512 Female, age 67, right hemisphere 54.9
2676 Female, age 94, right hemisphere 52.6
2264 Female, age 91, right hemisphere 48.9
Temporo-occipital transitional zone
nTPM: 73.8
1793 Male, age 80, right hemisphere 95.6
1900 Male, age 76, left hemisphere 76.8
2251 Female, age 85, right hemisphere 49.0
Transversal temporal gyrus, anterior
nTPM: 75.5
1888 Female, age 91, left hemisphere 101.2
1910 Male, age 80, right hemisphere 78.7
1809 Male, age 76, right hemisphere 72.6
2522 Female, age 94, left hemisphere 64.2
2610 Male, age 75, right hemisphere 60.8
Transversal temporal gyrus, posterior
nTPM: 69.1
2833 Male, age 80, right hemisphere 78.6
1967 Female, age 91, right hemisphere 71.6
1922 Male, age 76, left hemisphere 69.2
2520 Male, age 75, right hemisphere 68.5
2614 Female, age 94, left hemisphere 57.8

CEREBRAL CORTEX - HPA PFC Brain RNA-seq
Max subtype nTPMi 76.9
Sample id Sample description nTPM
Anterior cingulate gyrus, pregenual-dorsal
nTPM: 67.2
1515 Female, age 94, right hemisphere 91.5
1516 Female, age 85, left hemisphere 84.5
1510 Male, age 61, left hemisphere 76.8
1511 Male, age 61, right hemisphere 71.1
1514 Male, age 74, right hemisphere 70.7
1512 Male, age 75, left hemisphere 56.6
1517 Female, age 67, left hemisphere 53.8
1513 Male, age 74, left hemisphere 51.2
1518 Female, age 67, right hemisphere 48.9
Anterior cingulate gyrus, pregenual-ventral
nTPM: 59.1
1519 Male, age 61, left hemisphere 65.9
1521 Male, age 74, left hemisphere 62.5
1522 Male, age 74, right hemisphere 60.2
1520 Male, age 75, right hemisphere 53.6
1523 Female, age 67, left hemisphere 53.2
Anterior cingulate gyrus, subgenual
nTPM: 66.0
1529 Female, age 85, left hemisphere 105.3
1524 Male, age 61, left hemisphere 69.4
1525 Male, age 75, left hemisphere 62.0
1526 Male, age 75, right hemisphere 61.7
1527 Male, age 74, left hemisphere 58.3
1530 Female, age 67, right hemisphere 57.4
1528 Male, age 74, right hemisphere 47.6
Dorsolateral prefrontal cortex
nTPM: 62.6
1447 Female, age 94, left hemisphere 85.2
1448 Female, age 94, right hemisphere 68.3
1445 Male, age 75, right hemisphere 68.1
1449 Female, age 85, right hemisphere 57.8
1444 Male, age 75, left hemisphere 55.0
1450 Female, age 67, right hemisphere 52.8
1446 Male, age 74, right hemisphere 50.7
Dorsomedial prefrontal cortex
nTPM: 69.0
1442 Male, age 75, right hemisphere 78.0
1439 Male, age 61, left hemisphere 76.2
1440 Male, age 61, right hemisphere 74.5
1441 Male, age 75, left hemisphere 65.4
1443 Female, age 67, right hemisphere 51.0
Frontal cortex
nTPM: 70.5
1581 Female, age 85, right hemisphere 94.9
1578 Female, age 94, left hemisphere 86.6
1580 Female, age 85, left hemisphere 86.0
1572 Male, age 61, left hemisphere 83.5
1579 Female, age 94, right hemisphere 78.3
1573 Male, age 61, right hemisphere 73.5
1575 Male, age 75, right hemisphere 63.5
1583 Female, age 67, right hemisphere 60.5
1582 Female, age 67, left hemisphere 57.8
1576 Male, age 74, left hemisphere 57.4
1574 Male, age 75, left hemisphere 55.7
1577 Male, age 74, right hemisphere 48.6
Frontomarginal cortex
nTPM: 73.0
1466 Male, age 61, right hemisphere 104.8
1465 Male, age 61, left hemisphere 92.5
1471 Female, age 85, left hemisphere 85.6
1470 Female, age 94, right hemisphere 68.6
1469 Female, age 94, left hemisphere 68.1
1473 Female, age 67, right hemisphere 66.2
1467 Male, age 75, right hemisphere 65.6
1468 Male, age 74, left hemisphere 55.5
1472 Female, age 67, left hemisphere 50.1
Frontopolar cortex
nTPM: 73.9
1459 Male, age 61, right hemisphere 120.6
1458 Male, age 61, left hemisphere 90.9
1462 Female, age 94, left hemisphere 65.0
1460 Male, age 75, left hemisphere 64.7
1461 Male, age 75, right hemisphere 64.2
1464 Female, age 67, right hemisphere 60.5
1463 Female, age 67, left hemisphere 51.7
Gyrus rectus
nTPM: 71.6
1475 Male, age 61, right hemisphere 99.6
1478 Female, age 94, left hemisphere 83.1
1479 Female, age 94, right hemisphere 78.5
1480 Female, age 85, left hemisphere 77.6
1477 Male, age 75, right hemisphere 63.5
1474 Male, age 61, left hemisphere 61.3
1476 Male, age 75, left hemisphere 56.5
1481 Female, age 67, left hemisphere 52.6
Inferior frontal gyrus, orbital
nTPM: 68.8
1501 Male, age 61, right hemisphere 100.9
1506 Female, age 94, left hemisphere 88.0
1508 Female, age 85, right hemisphere 86.1
1500 Male, age 61, left hemisphere 77.6
1502 Male, age 75, left hemisphere 67.1
1505 Male, age 74, right hemisphere 63.9
1503 Male, age 75, right hemisphere 62.5
1509 Female, age 67, right hemisphere 59.4
1504 Male, age 74, left hemisphere 49.3
1507 Female, age 85, left hemisphere 33.6
Inferior frontal gyrus, triangular
nTPM: 67.1
1546 Female, age 94, right hemisphere 85.8
1548 Female, age 85, right hemisphere 73.6
1542 Male, age 61, left hemisphere 71.7
1544 Male, age 75, right hemisphere 71.4
1543 Male, age 61, right hemisphere 63.4
1547 Female, age 85, left hemisphere 60.2
1545 Male, age 74, right hemisphere 59.1
1549 Female, age 67, left hemisphere 51.5
Orbitofrontal gyrus, lateral
nTPM: 73.3
1498 Female, age 85, right hemisphere 90.4
1493 Male, age 61, right hemisphere 89.7
1497 Female, age 85, left hemisphere 77.9
1495 Female, age 94, left hemisphere 71.6
1496 Female, age 94, right hemisphere 69.7
1494 Male, age 75, left hemisphere 60.0
1499 Female, age 67, right hemisphere 53.5
Orbitofrontal gyrus, medial
nTPM: 64.1
1482 Male, age 61, left hemisphere 84.8
1487 Female, age 94, left hemisphere 79.9
1488 Female, age 94, right hemisphere 71.5
1490 Female, age 85, right hemisphere 68.4
1484 Male, age 75, right hemisphere 68.3
1483 Male, age 75, left hemisphere 64.0
1489 Female, age 85, left hemisphere 61.2
1485 Male, age 74, left hemisphere 60.8
1491 Female, age 67, left hemisphere 51.6
1486 Male, age 74, right hemisphere 49.0
1492 Female, age 67, right hemisphere 45.2
Orbitofrontal gyrus, posterior
nTPM: 71.5
1537 Female, age 94, right hemisphere 89.8
1531 Male, age 61, left hemisphere 86.7
1532 Male, age 61, right hemisphere 80.5
1536 Female, age 94, left hemisphere 80.1
1534 Male, age 75, right hemisphere 74.4
1533 Male, age 75, left hemisphere 70.6
1539 Female, age 85, right hemisphere 68.7
1538 Female, age 85, left hemisphere 64.8
1540 Female, age 67, left hemisphere 61.1
1541 Female, age 67, right hemisphere 60.4
1535 Male, age 74, left hemisphere 49.4
Subcallosal gyrus
nTPM: 62.1
1559 Female, age 85, right hemisphere 91.8
1558 Female, age 85, left hemisphere 82.9
1550 Male, age 61, left hemisphere 79.1
1551 Male, age 61, right hemisphere 65.3
1557 Female, age 94, right hemisphere 62.8
1552 Male, age 75, left hemisphere 61.2
1560 Female, age 67, left hemisphere 54.6
1554 Male, age 74, left hemisphere 52.2
1553 Male, age 75, right hemisphere 51.8
1561 Female, age 67, right hemisphere 50.3
1556 Female, age 94, left hemisphere 49.0
1555 Male, age 74, right hemisphere 44.1
Superior frontal gyrus
nTPM: 74.2
1562 Male, age 61, left hemisphere 93.7
1569 Female, age 85, left hemisphere 90.1
1567 Female, age 94, left hemisphere 89.6
1570 Female, age 85, right hemisphere 84.4
1563 Male, age 61, right hemisphere 80.4
1568 Female, age 94, right hemisphere 78.3
1565 Male, age 75, right hemisphere 65.1
1564 Male, age 75, left hemisphere 62.9
1566 Male, age 74, right hemisphere 48.6
1571 Female, age 67, right hemisphere 48.6
Temporal cortex
nTPM: 64.6
1591 Male, age 75, right hemisphere 82.7
1596 Female, age 85, right hemisphere 76.9
1594 Female, age 94, left hemisphere 71.8
1590 Male, age 61, right hemisphere 71.5
1595 Female, age 94, right hemisphere 67.6
1592 Male, age 74, left hemisphere 41.5
1593 Male, age 74, right hemisphere 40.3
Ventrolateral prefrontal cortex
nTPM: 59.3
1454 Female, age 94, left hemisphere 81.7
1455 Female, age 85, right hemisphere 66.5
1451 Male, age 75, right hemisphere 60.5
1453 Male, age 74, right hemisphere 57.9
1452 Male, age 74, left hemisphere 53.3
1456 Female, age 67, left hemisphere 51.1
1457 Female, age 67, right hemisphere 44.1
Ventromedial prefrontal cortex
nTPM: 76.9
1436 Female, age 85, left hemisphere 140.2
1432 Male, age 61, left hemisphere 82.4
1435 Female, age 94, right hemisphere 71.4
1437 Female, age 85, right hemisphere 71.4
1433 Male, age 61, right hemisphere 66.4
1438 Female, age 67, left hemisphere 54.5
1434 Male, age 75, right hemisphere 51.9

CEREBRAL CORTEX - GTEx RNA-seqi
Max subtype nTPMi 104.2
GTEx sample id Sample description nTPM
Brain - Anterior cingulate cortex (BA24)
Average nTPM: 93.0
Samples: 176

Max nTPM: 145.7
Min nTPM: 57.5
Std nTPM: 17.5
Median nTPM: 91.3
GTEX-11DZ1-0011-R3a-SM-DNZYY 50-59 years, male 145.7
GTEX-1C6WA-0011-R3a-SM-9OSVP 60-69 years, male 136.4
GTEX-12WSC-0011-R3a-SM-5P9F1 50-59 years, male 135.3
GTEX-YFC4-0011-R3a-SM-4RGLP 40-49 years, female 133.8
GTEX-1B933-0011-R3b-SM-7P8PL 50-59 years, female 127.1
GTEX-P44G-0011-R3A-SM-2I3FC 30-39 years, male 126.1
GTEX-13IVO-0011-R3b-SM-5IJBJ 70-79 years, male 124.9
GTEX-14PN4-0011-R3b-SM-686ZU 50-59 years, male 124.6
GTEX-16YQH-0011-R3a-SM-7EPGM 30-39 years, male 124.4
GTEX-1GMR8-0011-R3b-SM-9QEIG 50-59 years, female 123.8
GTEX-Q2AG-0011-R3A-SM-2HMJ9 40-49 years, female 123.3
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Brain - Cortex
Average nTPM: 93.7
Samples: 255

Max nTPM: 140.0
Min nTPM: 61.6
Std nTPM: 13.8
Median nTPM: 95.1
GTEX-1F48J-2826-SM-7P8R4 50-59 years, female 140.0
GTEX-1EMGI-3026-SM-7P8P6 60-69 years, male 128.4
GTEX-13SLX-3126-SM-5S2Q5 50-59 years, female 128.2
GTEX-1C6WA-3026-SM-7P8RQ 60-69 years, male 126.8
GTEX-117XS-3026-SM-5N9CA 60-69 years, male 122.3
GTEX-15EO6-3026-SM-7KUMA 50-59 years, male 121.0
GTEX-P44G-2426-SM-2I5ER 30-39 years, male 119.2
GTEX-12ZZW-2926-SM-5LZUP 50-59 years, male 118.5
GTEX-12WSC-3026-SM-5GCNF 50-59 years, male 117.0
GTEX-WVLH-3026-SM-3MJG9 50-59 years, male 116.7
GTEX-15G19-2926-SM-7KUFL 60-69 years, male 116.3
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Brain - Frontal Cortex (BA9)
Average nTPM: 104.2
Samples: 209

Max nTPM: 168.1
Min nTPM: 60.8
Std nTPM: 18.1
Median nTPM: 103.4
GTEX-13NYS-0011-R10a-SM-5MR4S 60-69 years, male 168.1
GTEX-1GF9V-0011-R10b-SM-CKZNP 60-69 years, male 158.5
GTEX-1192X-0011-R10a-SM-DO941 50-59 years, male 149.1
GTEX-NL3H-0011-R10A-SM-2I3E9 60-69 years, male 147.5
GTEX-1EX96-0011-R10b-SM-CE6QR 50-59 years, male 145.6
GTEX-1HFI6-0011-R10b-SM-ARZLO 40-49 years, male 143.3
GTEX-12ZZY-0011-R10b-SM-5HL7W 60-69 years, male 142.1
GTEX-PVOW-0011-R10A-SM-EXOHB 40-49 years, male 140.8
GTEX-14BIN-0011-R10a-SM-5S2UA 50-59 years, female 140.1
GTEX-1HB9E-0011-R10a-SM-CJI3H 50-59 years, male 139.9
GTEX-13RTJ-0011-R10b-SM-5O9CW 60-69 years, male 139.2
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CEREBRAL CORTEX - FANTOM5 CAGEi
Max subtype Scaled Tags Per Millioni 118.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Occipital cortex
Scaled Tags Per Million: 68.5
FF:10163-103B1 76 years, female 68.5
Postcentral gyrus
Scaled Tags Per Million: 107.2
FF:10032-101E5 44-52 years, mixed 107.2
Frontal lobe
Scaled Tags Per Million: 69.0
FF:10040-101F4 32-61 years, mixed 69.0
Insula
Scaled Tags Per Million: 81.5
FF:10039-101F3 20-68 years, mixed 81.5
Medial frontal gyrus
Scaled Tags Per Million: 79.4
FF:10150-102I6 76 years, female 79.4
Medial temporal gyrus
Scaled Tags Per Million: 99.7
FF:10183-103D3 60 years, female 118.5
FF:10156-103A3 76 years, female 80.9
Occipital lobe
Scaled Tags Per Million: 118.2
FF:10076-102A4 27 years, male 118.2
Occipital pole
Scaled Tags Per Million: 104.5
FF:10036-101E9 22-68 years, mixed 104.5
Paracentral gyrus
Scaled Tags Per Million: 94.5
FF:10035-101E8 22-69 years, mixed 94.5
Parietal lobe
Scaled Tags Per Million: 100.1
FF:10171-103B9 60 years, female 119.7
FF:10034-101E7 35-89 years, mixed 94.2
FF:10157-103A4 76 years, female 86.5
Temporal lobe
Scaled Tags Per Million: 112.6
FF:10031-101E4 32-61 years, mixed 112.6

CEREBRAL CORTEX - Pig RNA-seqi
Max subtype nTPMi 72.4
Pig sample Sample description nTPM
Occipital cortex
nTPM: 63.4
Samples: 4

Max nTPM: 74.3
Min nTPM: 55.7
Sample A Female 62.8
Sample B Female 55.7
Sample C Male 74.3
Sample D Male 60.6
Retrosplenial cortex
nTPM: 56.9
Samples: 4

Max nTPM: 67.3
Min nTPM: 48.3
Sample A Female 57.8
Sample B Female 54.2
Sample C Male 67.3
Sample D Male 48.3
Cingulate cortex
nTPM: 59.9
Samples: 4

Max nTPM: 69.1
Min nTPM: 51.4
Sample A Female 66.2
Sample B Female 51.4
Sample C Male 69.1
Sample D Male 52.9
Insular cortex
nTPM: 52.3
Samples: 4

Max nTPM: 62.3
Min nTPM: 42.6
Sample A Female 62.3
Sample B Female 42.6
Sample C Male 60.0
Sample D Male 44.4
Motor cortex
nTPM: 65.5
Samples: 4

Max nTPM: 76.0
Min nTPM: 57.3
Sample A Female 66.3
Sample B Female 62.2
Sample C Male 76.0
Sample D Male 57.3
Prefrontal cortex
nTPM: 60.8
Samples: 4

Max nTPM: 64.2
Min nTPM: 56.5
Sample A Female 61.6
Sample B Female 64.2
Sample C Male 60.9
Sample D Male 56.5
Somatosensory cortex
nTPM: 72.4
Samples: 3

Max nTPM: 78.6
Min nTPM: 61.8
Sample B Female 61.8
Sample C Male 78.6
Sample D Male 76.7
Temporal cortex
nTPM: 60.2
Samples: 4

Max nTPM: 68.7
Min nTPM: 56.5
Sample A Female 56.5
Sample B Female 57.1
Sample C Male 68.7
Sample D Male 58.3

CEREBRAL CORTEX - Mouse RNA-seqi
Max subtype nTPMi 139.1
Mouse sample Sample description nTPM
Occipital cortex
nTPM: 133.4
Samples: 4

Max nTPM: 149.5
Min nTPM: 119.0
Sample A Male 149.5
Sample B Male 135.5
Sample C Female 119.0
Sample D Female 129.5
Frontal cortex
nTPM: 135.9
Samples: 4

Max nTPM: 144.5
Min nTPM: 120.1
Sample A Male 140.4
Sample B Male 144.5
Sample C Female 120.1
Sample D Female 138.6
Retrosplenial and cingulate cortex
nTPM: 139.1
Samples: 4

Max nTPM: 153.1
Min nTPM: 130.3
Sample A Male 130.3
Sample B Male 153.1
Sample C Female 130.7
Sample D Female 142.3
Somatosensory cortex
nTPM: 131.3
Samples: 4

Max nTPM: 137.4
Min nTPM: 119.2
Sample A Male 137.4
Sample B Male 132.7
Sample C Female 119.2
Sample D Female 136.0

CEREBRAL CORTEX - Allen Mouse ISHi
Max subtype Expression energyi 19.7
Allen experiment id Experiment description Expression energy
Cerebral cortex
Expression energy: 19.7
81600108 Antisense, RP_080205_02_D01, Mouse strain C57BL/6J (56 days, male) 20.2
413791 Antisense, RP_040809_01_E01, Mouse strain C57BL/6J (56 days, male) 19.2

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