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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
High
Hepatocytes:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
110.6
nTPM
HPA:
110.6
nTPM
GTEx:
92.4
nTPM
FANTOM5:
130.5
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA008425
Cholangiocytes
High
Hepatocytes
Medium
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
110.6
Female, age 60
Liver sample 21 nTPM: 99.8
Male, age 54
Liver sample 23 nTPM: 87.6
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 96.3
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 117.7
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 109.2
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 119.9
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 117.4
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 107.2
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 104.3
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 146.1
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
92.4
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 92.4
Samples: 226
Max nTPM: 219.7
Min nTPM: 34.8
Std nTPM: 31.7
Median nTPM: 87.4
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
219.7
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
178.9
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
168.9
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
167.9
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
164.9
GTEX-S32W-1926-SM-4AD63
50-59 years, female
162.3
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
160.2
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
156.5
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
156.3
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
155.0
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
155.0
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
151.8
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
148.9
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
147.6
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
146.9
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
145.5
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
145.1
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
142.2
GTEX-14XAO-0226-SM-68728
60-69 years, female
141.9
GTEX-P78B-1326-SM-3P611
40-49 years, female
140.5
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
134.4
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
134.1
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
131.7
GTEX-QEL4-1226-SM-447A4
50-59 years, male
131.7
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
131.6
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
131.4
GTEX-R53T-0326-SM-48FEC
50-59 years, female
131.1
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
130.0
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
129.1
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
128.4
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
127.6
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
126.8
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
126.7
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
125.9
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
125.6
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
125.6
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
125.2
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
125.0
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
124.9
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
123.8
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
123.5
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
122.8
GTEX-12696-0826-SM-5EGGE
60-69 years, male
122.7
GTEX-18A66-2026-SM-7189C
60-69 years, male
122.7
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
121.5
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
121.3
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
121.0
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
120.8
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
117.6
GTEX-Q734-0326-SM-48U15
40-49 years, female
117.6
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
117.1
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
116.9
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
116.1
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
115.7
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
115.4
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
115.3
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
114.2
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
113.6
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
113.5
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
113.0
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
112.1
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
111.9
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
111.2
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
111.0
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
110.5
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
110.3
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
109.6
GTEX-13113-1326-SM-5GCOI
60-69 years, female
109.0
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
108.2
GTEX-QESD-2026-SM-447BI
20-29 years, male
108.2
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
108.0
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
107.9
GTEX-17HHE-0126-SM-79398
50-59 years, male
105.8
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
105.6
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
105.3
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
103.0
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
102.9
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
102.6
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
102.3
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
102.1
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
101.8
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
101.7
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
101.4
GTEX-1B932-1426-SM-793AN
40-49 years, female
100.1
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
99.8
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
99.6
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
99.2
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
98.6
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
98.1
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
97.5
GTEX-14PHX-0526-SM-664NW
50-59 years, male
96.5
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
96.4
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
95.5
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
95.2
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
94.5
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
93.6
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
93.3
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
92.8
GTEX-O5YV-0726-SM-EV798
60-69 years, female
92.6
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
92.5
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
92.0
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
91.9
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
91.3
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
90.6
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
90.5
GTEX-18A7A-1526-SM-72D69
50-59 years, female
90.3
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
89.8
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
89.5
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
89.4
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
87.6
GTEX-S33H-1626-SM-4AD68
30-39 years, male
87.6
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
87.5
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
87.5
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
87.4
GTEX-14JG1-1626-SM-664NH
40-49 years, male
87.3
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
87.1
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
86.9
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
86.6
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
84.8
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
84.2
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
83.9
GTEX-14E7W-1526-SM-6871X
70-79 years, male
83.8
GTEX-REY6-1226-SM-48FDR
60-69 years, male
83.7
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
82.9
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
82.9
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
82.7
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
82.2
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
81.7
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
80.7
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
80.5
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
79.6
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
79.1
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
79.1
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
78.6
GTEX-RU72-1426-SM-46MUF
50-59 years, female
78.6
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
78.5
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
78.4
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
77.7
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
77.2
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
77.0
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
76.8
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
76.3
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
76.1
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
75.8
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
75.8
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
75.6
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
75.3
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
74.2
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
74.0
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
73.8
GTEX-13112-1426-SM-5EGH8
50-59 years, male
73.2
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
72.1
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
72.0
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
72.0
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
71.5
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
71.3
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
70.7
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
70.6
GTEX-14PJO-1726-SM-68719
60-69 years, male
70.4
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
70.3
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
70.1
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
69.8
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
69.8
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
68.6
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
68.5
GTEX-X261-1726-SM-4PQYT
50-59 years, male
68.0
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
68.0
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
67.7
GTEX-YECK-1926-SM-4W21H
60-69 years, male
67.3
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
67.1
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
67.1
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
66.8
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
66.6
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
66.0
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
65.8
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
65.2
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
65.0
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
64.3
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
64.2
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
63.9
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
63.7
GTEX-1399T-0826-SM-5IFES
60-69 years, male
63.3
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
62.7
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
62.4
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
62.3
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
62.3
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
62.0
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
61.9
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
61.7
GTEX-1B933-1226-SM-731DW
50-59 years, female
61.3
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
60.5
GTEX-18465-1626-SM-7LG6N
50-59 years, male
60.5
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
60.4
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
60.3
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
59.7
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
59.3
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
58.3
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
58.1
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
57.0
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
56.4
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
56.4
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
56.3
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
56.2
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
56.2
GTEX-17F96-1226-SM-79OK2
70-79 years, male
56.0
GTEX-11ZUS-2526-SM-59872
30-39 years, male
55.7
GTEX-144GL-1426-SM-79OMA
50-59 years, male
55.4
GTEX-RN64-1826-SM-48FDV
50-59 years, male
54.5
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
54.5
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
53.7
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
53.0
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
52.0
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
51.5
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
51.2
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
50.7
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
49.7
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
47.4
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
47.2
GTEX-11GSP-0626-SM-5986T
60-69 years, female
47.0
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
45.8
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
45.3
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
44.0
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
43.0
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
41.8
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
41.2
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
34.8
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
