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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
272.3
nTPM
HPA:
272.3
nTPM
GTEx:
117.3
nTPM
FANTOM5:
216.4
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA007316
Antibody HPA007571
Antibody CAB008636
Cholangiocytes
Not detected
Low
Low
Hepatocytes
Medium
Low
Medium
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
272.3
Female, age 60
Liver sample 21 nTPM: 213.8
Male, age 54
Liver sample 23 nTPM: 124.1
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 294.7
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 266.1
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 390.9
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 176.2
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 337.6
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 468
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 194.8
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 257
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
117.3
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 117.3
Samples: 226
Max nTPM: 389.7
Min nTPM: 30.9
Std nTPM: 59.7
Median nTPM: 104.4
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
389.7
GTEX-QESD-2026-SM-447BI
20-29 years, male
316.3
GTEX-14PHX-0526-SM-664NW
50-59 years, male
284.1
GTEX-11ZUS-2526-SM-59872
30-39 years, male
282.2
GTEX-13112-1426-SM-5EGH8
50-59 years, male
260.3
GTEX-RN64-1826-SM-48FDV
50-59 years, male
258.3
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
254.7
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
253.5
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
248.3
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
247.5
GTEX-14E7W-1526-SM-6871X
70-79 years, male
242.8
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
236.8
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
236.7
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
227.9
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
225.8
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
221.2
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
212.2
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
206.5
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
205.7
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
201.7
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
198.6
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
195.2
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
192.8
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
191.9
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
190.0
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
189.2
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
187.0
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
184.8
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
183.5
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
183.1
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
181.4
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
178.7
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
177.3
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
176.5
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
176.2
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
174.1
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
172.7
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
169.5
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
169.2
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
169.2
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
168.7
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
168.3
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
166.7
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
164.9
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
164.2
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
164.1
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
163.4
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
163.3
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
159.8
GTEX-18A7A-1526-SM-72D69
50-59 years, female
159.2
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
158.7
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
158.3
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
158.0
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
155.4
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
155.0
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
154.5
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
152.6
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
151.9
GTEX-144GL-1426-SM-79OMA
50-59 years, male
151.6
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
151.2
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
150.5
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
150.3
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
148.9
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
148.7
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
148.2
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
145.7
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
144.7
GTEX-14JG1-1626-SM-664NH
40-49 years, male
143.3
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
143.2
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
139.4
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
139.0
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
138.4
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
135.3
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
133.6
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
133.2
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
130.7
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
130.5
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
129.9
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
129.5
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
129.4
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
129.2
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
127.7
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
126.6
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
125.5
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
124.9
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
123.3
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
121.8
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
120.3
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
120.2
GTEX-17HHE-0126-SM-79398
50-59 years, male
119.9
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
119.4
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
118.6
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
117.4
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
116.9
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
115.6
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
115.6
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
114.4
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
114.2
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
110.9
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
110.4
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
109.6
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
108.3
GTEX-17F96-1226-SM-79OK2
70-79 years, male
108.1
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
107.9
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
107.9
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
107.8
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
107.5
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
107.5
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
106.4
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
105.7
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
105.5
GTEX-S32W-1926-SM-4AD63
50-59 years, female
105.5
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
104.7
GTEX-18465-1626-SM-7LG6N
50-59 years, male
104.0
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
103.0
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
102.9
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
102.9
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
102.5
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
102.1
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
101.2
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
100.9
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
100.8
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
100.5
GTEX-1399T-0826-SM-5IFES
60-69 years, male
100.4
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
100.4
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
98.5
GTEX-YECK-1926-SM-4W21H
60-69 years, male
98.5
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
98.4
GTEX-1B933-1226-SM-731DW
50-59 years, female
96.8
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
96.8
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
95.5
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
94.4
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
94.2
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
93.7
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
93.5
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
92.4
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
92.2
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
91.8
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
90.8
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
90.8
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
90.5
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
89.3
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
88.5
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
86.6
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
86.5
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
85.5
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
84.8
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
84.4
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
84.3
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
83.4
GTEX-12696-0826-SM-5EGGE
60-69 years, male
83.3
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
82.8
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
82.2
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
82.2
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
81.7
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
81.5
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
81.1
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
79.6
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
78.5
GTEX-11GSP-0626-SM-5986T
60-69 years, female
78.4
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
78.2
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
77.7
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
77.3
GTEX-14XAO-0226-SM-68728
60-69 years, female
76.3
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
75.4
GTEX-1B932-1426-SM-793AN
40-49 years, female
74.7
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
74.0
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
72.9
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
72.3
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
71.9
GTEX-18A66-2026-SM-7189C
60-69 years, male
70.1
GTEX-13113-1326-SM-5GCOI
60-69 years, female
69.7
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
67.9
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
67.7
GTEX-X261-1726-SM-4PQYT
50-59 years, male
67.4
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
66.5
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
65.9
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
65.4
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
64.5
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
62.9
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
62.6
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
62.5
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
62.5
GTEX-QEL4-1226-SM-447A4
50-59 years, male
62.0
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
61.9
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
61.3
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
60.8
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
60.4
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
60.2
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
59.9
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
59.7
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
59.0
GTEX-P78B-1326-SM-3P611
40-49 years, female
58.6
GTEX-S33H-1626-SM-4AD68
30-39 years, male
58.6
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
58.5
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
58.5
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
57.8
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
57.0
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
57.0
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
55.6
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
55.1
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
54.4
GTEX-Q734-0326-SM-48U15
40-49 years, female
53.2
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
52.6
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
52.4
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
52.4
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
52.1
GTEX-R53T-0326-SM-48FEC
50-59 years, female
51.6
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
51.1
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
50.5
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
49.7
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
49.2
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
46.2
GTEX-RU72-1426-SM-46MUF
50-59 years, female
45.2
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
45.1
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
45.0
GTEX-14PJO-1726-SM-68719
60-69 years, male
44.9
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
43.6
GTEX-REY6-1226-SM-48FDR
60-69 years, male
42.0
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
38.8
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
33.3
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
33.3
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
32.6
GTEX-O5YV-0726-SM-EV798
60-69 years, female
32.3
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
31.6
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
30.9
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
