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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:260.4 nTPM
HPA Brain:193.3 nTPM
GTEx:260.4 nTPM
FANTOM5:220.8 Scaled Tags Per Million
Pig:307.0 nTPM
Mouse:229.9 nTPM
Allen mouse:10.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

193.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 178.5
2586 Male, age 75, left hemisphere 201.7
2019 Male, age 18, unknown 196.8
1870 Female, age 42, unknown 196.7
2666 Male, age 74, left hemisphere 194.8
2411 Female, age 72, unknown 180.6
1833 Male, age 53, unknown 174.3
1830 Male, age 51, unknown 172.7
2828 Female, age 72, unknown 167.3
1827 Male, age 72, unknown 157.8
2219 Male, age 76, both hemispheres 142.0
Dorsal raphe nucleus
nTPM: 169.7
2750 Male, age 76, both hemispheres 202.0
2016 Female, age 72, unknown 172.0
2047 Male, age 72, unknown 169.1
2298 Female, age 72, unknown 154.4
1828 Male, age 53, unknown 151.1
Inferior colliculus
nTPM: 155.1
1890 Male, age 53, unknown 165.1
2097 Female, age 72, unknown 161.9
1848 Female, age 42, unknown 150.6
2849 Male, age 72, unknown 142.8
Median raphe nucleus
nTPM: 145.7
2220 Male, age 76, midline 145.7
Periaquaductal grey, anterior
nTPM: 173.5
1947 Male, age 18, unknown 181.7
2502 Female, age 75, unknown 181.0
1795 Male, age 51, unknown 157.7
Periaquaductal grey, dorsal
nTPM: 143.7
2464 Female, age 72, unknown 152.5
2850 Male, age 76, both hemispheres 143.1
1840 Male, age 53, unknown 143.0
1831 Male, age 72, unknown 136.1
Periaquaductal grey, lateral
nTPM: 158.0
2272 Male, age 74, both hemispheres 166.2
2140 Male, age 76, both hemispheres 160.4
2053 Male, age 18, unknown 147.3
Pretectal area
nTPM: 167.1
2007 Male, age 72, unknown 202.3
1815 Male, age 53, unknown 188.9
1817 Female, age 42, unknown 187.1
1944 Female, age 72, unknown 178.5
1816 Male, age 51, unknown 172.8
2316 Male, age 76, right hemisphere 172.5
2224 Female, age 72, unknown 165.2
2273 Male, age 74, both hemispheres 162.8
2825 Male, age 18, unknown 142.4
2407 Male, age 75, both hemispheres 139.6
2667 Female, age 75, unknown 126.1
Red nucleus
nTPM: 193.3
2503 Female, age 72, unknown 218.3
2785 Male, age 18, unknown 214.8
2588 Male, age 74, left hemisphere 211.0
2769 Male, age 72, unknown 205.6
2227 Male, age 72, unknown 202.3
1904 Male, age 53, unknown 195.6
1821 Female, age 72, unknown 194.6
1865 Male, age 51, unknown 191.0
1954 Female, age 42, unknown 184.8
2725 Female, age 75, unknown 182.1
2584 Male, age 75, left hemisphere 161.9
2823 Male, age 76, right hemisphere 157.4
Substantia nigra
nTPM: 175.6
2590 Female, age 75, unknown 198.8
1916 Female, age 42, unknown 185.6
1851 Male, age 51, unknown 183.4
1941 Male, age 53, unknown 183.1
2665 Male, age 74, both hemispheres 180.2
1889 Female, age 72, unknown 176.0
2409 Female, age 72, unknown 170.0
2241 Male, age 72, unknown 166.2
2583 Male, age 75, right hemisphere 157.5
2699 Male, age 18, unknown 155.3
Superior colliculus
nTPM: 168.0
2668 Female, age 75, unknown 195.1
1913 Female, age 42, unknown 191.3
2587 Male, age 74, left hemisphere 190.0
2261 Male, age 18, unknown 180.4
1995 Male, age 72, unknown 164.4
1839 Male, age 51, unknown 164.1
1796 Male, age 53, unknown 157.1
2087 Female, age 72, unknown 149.3
1895 Male, age 76, right hemisphere 147.1
2664 Male, age 75, both hemispheres 141.1
Ventral tegmental area
nTPM: 174.3
2410 Female, age 72, unknown 184.9
1942 Male, age 51, unknown 183.9
2223 Female, age 72, unknown 183.5
1915 Female, age 42, unknown 172.0
2021 Male, age 53, unknown 163.3
2218 Male, age 76, both hemispheres 158.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

260.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 260.4
Samples: 139

Max nTPM: 552.5
Min nTPM: 156.1
Std nTPM: 72.1
Median nTPM: 252.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 552.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 478.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 458.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 433.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 423.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 396.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 383.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 383.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 381.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 380.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 374.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 366.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 351.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 351.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 346.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 342.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 341.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 340.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 338.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 337.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 333.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 333.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 332.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 330.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 327.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 319.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 318.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 317.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 316.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 315.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 311.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 310.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 306.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 306.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 305.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 305.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 295.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 295.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 292.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 292.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 290.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 289.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 288.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 287.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 287.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 286.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 286.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 286.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 285.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 284.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 283.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 281.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 281.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 277.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 270.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 269.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 268.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 268.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 267.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 267.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 267.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 266.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 262.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 262.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 262.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 258.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 256.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 254.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 254.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 252.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 249.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 248.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 242.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 238.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 238.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 237.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 237.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 231.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 226.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 224.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 223.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 222.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 222.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 220.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 220.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 219.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 219.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 218.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 218.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 217.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 217.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 216.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 215.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 214.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 214.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 213.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 213.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 211.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 210.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 210.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 209.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 208.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 206.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 202.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 202.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 201.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 201.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 201.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 201.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 200.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 199.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 199.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 197.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 195.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 192.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 191.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 186.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 185.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 185.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 183.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 183.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 183.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 182.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 181.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 181.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 179.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 178.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 178.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 177.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 175.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 173.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 171.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 170.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 169.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 167.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 166.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 165.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 160.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 156.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

220.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 220.8
FF:10158-103A5 76 years, female 220.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

307.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 286.6
Samples: 4

Max nTPM: 325.4
Min nTPM: 247.9
Sample A Female 325.4
Sample B Female 247.9
Sample C Male 258.7
Sample D Male 314.2
Midbrain
nTPM: 307.1
Samples: 4

Max nTPM: 469.7
Min nTPM: 224.0
Sample A Female 469.7
Sample B Female 264.9
Sample C Male 269.6
Sample D Male 224.0
Periaqueductal gray
nTPM: 239.2
Samples: 3

Max nTPM: 258.7
Min nTPM: 221.6
Sample B Female 237.3
Sample C Male 258.7
Sample D Male 221.6
Superior colliculi
nTPM: 269.0
Samples: 4

Max nTPM: 293.9
Min nTPM: 243.2
Sample A Female 293.9
Sample B Female 243.2
Sample C Male 268.2
Sample D Male 270.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

229.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 229.9
Samples: 4

Max nTPM: 239.5
Min nTPM: 221.7
Sample A Male 221.7
Sample B Male 225.0
Sample C Female 239.5
Sample D Female 233.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

10.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 10.1
68191504 Antisense, RP_041129_01_C10, Mouse strain C57BL/6J (56 days, male) 10.1

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