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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:291.0 nTPM
HPA Brain:443.7 nTPM
GTEx:291.0 nTPM
FANTOM5:1088.4 Scaled Tags Per Million
Pig:493.9 nTPM
Mouse:124.5 nTPM
Allen mouse:10.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

443.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 306.8
1870 Female, age 42, unknown 443.1
1830 Male, age 51, unknown 425.8
1833 Male, age 53, unknown 382.8
2411 Female, age 72, unknown 365.4
2019 Male, age 18, unknown 346.3
2219 Male, age 76, both hemispheres 277.5
2828 Female, age 72, unknown 247.7
2666 Male, age 74, left hemisphere 228.4
1827 Male, age 72, unknown 188.6
2586 Male, age 75, left hemisphere 162.2
Dorsal raphe nucleus
nTPM: 229.1
2750 Male, age 76, both hemispheres 522.5
2016 Female, age 72, unknown 231.0
1828 Male, age 53, unknown 203.6
2047 Male, age 72, unknown 102.4
2298 Female, age 72, unknown 86.3
Inferior colliculus
nTPM: 190.0
2849 Male, age 72, unknown 214.0
1890 Male, age 53, unknown 201.1
1848 Female, age 42, unknown 198.9
2097 Female, age 72, unknown 146.0
Median raphe nucleus
nTPM: 263.8
2220 Male, age 76, midline 263.8
Periaquaductal grey, anterior
nTPM: 159.5
2502 Female, age 75, unknown 214.6
1947 Male, age 18, unknown 160.3
1795 Male, age 51, unknown 103.7
Periaquaductal grey, dorsal
nTPM: 120.7
2464 Female, age 72, unknown 193.3
1831 Male, age 72, unknown 138.3
2850 Male, age 76, both hemispheres 83.6
1840 Male, age 53, unknown 67.8
Periaquaductal grey, lateral
nTPM: 126.1
2053 Male, age 18, unknown 165.1
2272 Male, age 74, both hemispheres 139.2
2140 Male, age 76, both hemispheres 74.1
Pretectal area
nTPM: 176.1
2316 Male, age 76, right hemisphere 279.4
1815 Male, age 53, unknown 275.0
2407 Male, age 75, both hemispheres 224.8
1817 Female, age 42, unknown 197.4
2007 Male, age 72, unknown 192.3
2825 Male, age 18, unknown 179.9
2224 Female, age 72, unknown 133.4
2273 Male, age 74, both hemispheres 131.2
1944 Female, age 72, unknown 116.7
2667 Female, age 75, unknown 112.4
1816 Male, age 51, unknown 94.3
Red nucleus
nTPM: 443.7
1865 Male, age 51, unknown 654.0
1821 Female, age 72, unknown 560.5
2823 Male, age 76, right hemisphere 546.6
1904 Male, age 53, unknown 521.4
2503 Female, age 72, unknown 464.4
1954 Female, age 42, unknown 443.1
2227 Male, age 72, unknown 424.3
2769 Male, age 72, unknown 420.3
2785 Male, age 18, unknown 408.3
2725 Female, age 75, unknown 351.0
2588 Male, age 74, left hemisphere 300.1
2584 Male, age 75, left hemisphere 229.8
Substantia nigra
nTPM: 231.8
2409 Female, age 72, unknown 330.8
1851 Male, age 51, unknown 262.5
2699 Male, age 18, unknown 261.2
1889 Female, age 72, unknown 259.9
2241 Male, age 72, unknown 241.3
2590 Female, age 75, unknown 240.1
2583 Male, age 75, right hemisphere 214.2
1941 Male, age 53, unknown 190.7
1916 Female, age 42, unknown 160.9
2665 Male, age 74, both hemispheres 156.6
Superior colliculus
nTPM: 247.7
1913 Female, age 42, unknown 398.9
1995 Male, age 72, unknown 369.4
1895 Male, age 76, right hemisphere 333.6
2587 Male, age 74, left hemisphere 286.6
2668 Female, age 75, unknown 272.4
1839 Male, age 51, unknown 267.7
1796 Male, age 53, unknown 166.8
2664 Male, age 75, both hemispheres 136.4
2087 Female, age 72, unknown 135.2
2261 Male, age 18, unknown 109.6
Ventral tegmental area
nTPM: 273.9
2223 Female, age 72, unknown 450.8
2410 Female, age 72, unknown 282.4
2218 Male, age 76, both hemispheres 267.4
2021 Male, age 53, unknown 221.1
1942 Male, age 51, unknown 221.0
1915 Female, age 42, unknown 200.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

291.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 291.0
Samples: 139

Max nTPM: 915.4
Min nTPM: 61.8
Std nTPM: 161.6
Median nTPM: 260.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 915.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 846.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 823.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 639.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 636.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 635.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 628.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 615.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 606.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 551.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 543.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 537.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 501.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 499.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 493.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 492.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 487.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 486.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 486.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 476.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 447.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 440.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 434.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 434.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 432.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 429.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 406.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 396.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 388.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 387.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 387.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 369.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 362.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 350.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 349.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 349.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 349.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 349.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 348.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 347.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 346.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 336.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 336.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 334.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 333.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 333.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 333.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 332.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 331.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 330.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 323.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 321.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 318.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 316.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 312.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 307.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 299.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 296.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 294.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 290.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 288.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 288.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 285.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 284.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 279.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 277.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 276.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 270.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 267.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 260.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 259.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 256.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 252.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 248.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 244.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 242.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 235.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 231.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 228.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 226.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 221.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 220.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 219.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 217.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 217.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 213.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 211.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 206.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 202.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 201.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 196.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 195.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 194.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 193.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 187.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 187.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 186.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 182.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 181.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 174.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 173.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 172.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 172.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 171.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 168.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 165.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 163.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 159.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 159.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 155.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 154.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 152.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 150.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 146.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 144.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 143.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 143.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 139.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 139.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 136.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 133.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 128.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 127.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 125.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 120.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 120.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 118.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 118.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 117.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 116.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 115.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 115.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 99.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 94.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 86.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 85.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 77.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 63.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 61.8
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

1088.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 1088.4
FF:10158-103A5 76 years, female 1088.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

493.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 388.6
Samples: 4

Max nTPM: 656.2
Min nTPM: 222.2
Sample A Female 402.5
Sample B Female 222.2
Sample C Male 273.5
Sample D Male 656.2
Midbrain
nTPM: 493.8
Samples: 4

Max nTPM: 1093.4
Min nTPM: 195.3
Sample A Female 1093.4
Sample B Female 466.3
Sample C Male 195.3
Sample D Male 220.3
Periaqueductal gray
nTPM: 269.1
Samples: 3

Max nTPM: 315.6
Min nTPM: 179.6
Sample B Female 315.6
Sample C Male 179.6
Sample D Male 312.1
Superior colliculi
nTPM: 323.4
Samples: 4

Max nTPM: 421.8
Min nTPM: 163.1
Sample A Female 377.0
Sample B Female 163.1
Sample C Male 331.6
Sample D Male 421.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

124.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 124.5
Samples: 4

Max nTPM: 131.8
Min nTPM: 115.4
Sample A Male 115.4
Sample B Male 121.4
Sample C Female 131.8
Sample D Female 129.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

10.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 10.0
69448632 Antisense, RP_050419_02_F04, Mouse strain C57BL/6J (56 days, male) 10.0

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