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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:188.8 nTPM
HPA Brain:279.7 nTPM
GTEx:188.8 nTPM
FANTOM5:359.6 Scaled Tags Per Million
Pig:239.8 nTPM
Mouse:180.2 nTPM
Allen mouse:16.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

279.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 243.3
2586 Male, age 75, left hemisphere 336.9
1830 Male, age 51, unknown 260.7
2411 Female, age 72, unknown 255.7
2666 Male, age 74, left hemisphere 251.6
1833 Male, age 53, unknown 249.5
2019 Male, age 18, unknown 234.6
2828 Female, age 72, unknown 232.0
1870 Female, age 42, unknown 230.8
1827 Male, age 72, unknown 215.0
2219 Male, age 76, both hemispheres 165.8
Dorsal raphe nucleus
nTPM: 177.5
2750 Male, age 76, both hemispheres 261.6
1828 Male, age 53, unknown 174.4
2016 Female, age 72, unknown 165.7
2047 Male, age 72, unknown 144.8
2298 Female, age 72, unknown 141.1
Inferior colliculus
nTPM: 169.1
2849 Male, age 72, unknown 180.9
1890 Male, age 53, unknown 171.5
1848 Female, age 42, unknown 164.2
2097 Female, age 72, unknown 159.6
Median raphe nucleus
nTPM: 152.5
2220 Male, age 76, midline 152.5
Periaquaductal grey, anterior
nTPM: 184.4
1947 Male, age 18, unknown 198.3
1795 Male, age 51, unknown 180.2
2502 Female, age 75, unknown 174.8
Periaquaductal grey, dorsal
nTPM: 142.9
2464 Female, age 72, unknown 195.7
1831 Male, age 72, unknown 159.3
1840 Male, age 53, unknown 126.2
2850 Male, age 76, both hemispheres 90.4
Periaquaductal grey, lateral
nTPM: 149.9
2272 Male, age 74, both hemispheres 167.6
2053 Male, age 18, unknown 166.7
2140 Male, age 76, both hemispheres 115.4
Pretectal area
nTPM: 199.6
2407 Male, age 75, both hemispheres 261.7
2316 Male, age 76, right hemisphere 250.0
1815 Male, age 53, unknown 243.7
2007 Male, age 72, unknown 236.5
1817 Female, age 42, unknown 207.9
2825 Male, age 18, unknown 189.0
1816 Male, age 51, unknown 188.3
1944 Female, age 72, unknown 176.9
2667 Female, age 75, unknown 153.6
2224 Female, age 72, unknown 149.5
2273 Male, age 74, both hemispheres 138.8
Red nucleus
nTPM: 279.7
2823 Male, age 76, right hemisphere 314.1
1904 Male, age 53, unknown 310.7
2584 Male, age 75, left hemisphere 306.2
2503 Female, age 72, unknown 304.5
1865 Male, age 51, unknown 298.3
2785 Male, age 18, unknown 279.9
2227 Male, age 72, unknown 276.3
2588 Male, age 74, left hemisphere 275.7
2769 Male, age 72, unknown 269.7
2725 Female, age 75, unknown 249.3
1821 Female, age 72, unknown 240.5
1954 Female, age 42, unknown 230.7
Substantia nigra
nTPM: 218.8
2583 Male, age 75, right hemisphere 288.6
2590 Female, age 75, unknown 271.9
1851 Male, age 51, unknown 230.3
2409 Female, age 72, unknown 217.7
2665 Male, age 74, both hemispheres 210.7
1916 Female, age 42, unknown 207.2
1889 Female, age 72, unknown 205.2
2699 Male, age 18, unknown 204.2
1941 Male, age 53, unknown 189.5
2241 Male, age 72, unknown 163.1
Superior colliculus
nTPM: 236.3
1995 Male, age 72, unknown 285.0
1913 Female, age 42, unknown 278.0
2668 Female, age 75, unknown 277.8
1895 Male, age 76, right hemisphere 261.2
1796 Male, age 53, unknown 224.5
2664 Male, age 75, both hemispheres 223.6
2261 Male, age 18, unknown 213.9
1839 Male, age 51, unknown 210.0
2587 Male, age 74, left hemisphere 205.8
2087 Female, age 72, unknown 182.5
Ventral tegmental area
nTPM: 192.9
2410 Female, age 72, unknown 243.5
2223 Female, age 72, unknown 195.5
1915 Female, age 42, unknown 194.9
1942 Male, age 51, unknown 182.0
2218 Male, age 76, both hemispheres 174.7
2021 Male, age 53, unknown 166.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

188.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 188.8
Samples: 139

Max nTPM: 506.1
Min nTPM: 83.4
Std nTPM: 71.3
Median nTPM: 174.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 506.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 475.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 466.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 415.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 360.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 358.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 337.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 303.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 290.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 286.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 284.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 277.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 273.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 269.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 268.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 268.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 264.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 263.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 246.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 245.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 242.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 242.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 238.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 237.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 237.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 234.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 231.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 226.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 222.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 216.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 215.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 215.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 212.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 212.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 211.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 211.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 207.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 205.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 205.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 204.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 204.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 202.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 201.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 200.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 199.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 195.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 195.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 192.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 190.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 189.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 188.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 187.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 186.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 186.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 186.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 184.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 184.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 183.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 182.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 182.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 181.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 180.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 179.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 178.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 177.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 177.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 177.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 177.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 175.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 174.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 174.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 172.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 171.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 171.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 171.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 170.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 170.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 170.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 168.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 168.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 168.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 166.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 166.4
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 166.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 165.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 163.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 163.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 162.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 160.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 159.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 159.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 154.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 153.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 153.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 152.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 151.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 150.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 150.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 149.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 148.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 147.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 145.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 145.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 145.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 144.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 144.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 143.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 140.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 140.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 139.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 136.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 135.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 133.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 133.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 131.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 130.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 130.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 130.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 129.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 127.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 126.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 126.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 124.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 124.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 123.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 121.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 118.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 116.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 115.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 111.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 108.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 108.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 108.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 105.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 104.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 97.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 94.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 88.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 83.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

359.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 359.6
FF:10158-103A5 76 years, female 359.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

239.8
Pig sample Sample description nTPM
Substantia nigra
nTPM: 239.2
Samples: 4

Max nTPM: 341.3
Min nTPM: 160.4
Sample A Female 232.3
Sample B Female 160.4
Sample C Male 222.6
Sample D Male 341.3
Midbrain
nTPM: 239.8
Samples: 4

Max nTPM: 356.2
Min nTPM: 177.6
Sample A Female 356.2
Sample B Female 235.0
Sample C Male 190.4
Sample D Male 177.6
Periaqueductal gray
nTPM: 182.6
Samples: 3

Max nTPM: 195.7
Min nTPM: 172.9
Sample B Female 195.7
Sample C Male 172.9
Sample D Male 179.2
Superior colliculi
nTPM: 205.7
Samples: 4

Max nTPM: 245.0
Min nTPM: 128.0
Sample A Female 207.0
Sample B Female 128.0
Sample C Male 242.6
Sample D Male 245.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

180.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 180.2
Samples: 4

Max nTPM: 189.5
Min nTPM: 169.8
Sample A Male 189.5
Sample B Male 169.8
Sample C Female 181.3
Sample D Female 180.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

16.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 16.4
69529292 Antisense, RP_050421_03_H11, Mouse strain C57BL/6J (56 days, male) 16.4

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