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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:232.4 nTPM
HPA Brain:285.0 nTPM
GTEx:232.4 nTPM
FANTOM5:157.9 Scaled Tags Per Million
Pig:220.6 nTPM
Mouse:431.7 nTPM
Allen mouse:15.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

285.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 247.1
2586 Male, age 75, left hemisphere 382.1
2411 Female, age 72, unknown 283.4
2666 Male, age 74, left hemisphere 283.2
1827 Male, age 72, unknown 277.5
1870 Female, age 42, unknown 252.1
2828 Female, age 72, unknown 220.6
1833 Male, age 53, unknown 209.6
2019 Male, age 18, unknown 200.8
1830 Male, age 51, unknown 194.7
2219 Male, age 76, both hemispheres 167.1
Dorsal raphe nucleus
nTPM: 268.7
2298 Female, age 72, unknown 344.0
2047 Male, age 72, unknown 290.0
2750 Male, age 76, both hemispheres 260.1
1828 Male, age 53, unknown 243.8
2016 Female, age 72, unknown 205.7
Inferior colliculus
nTPM: 208.5
2097 Female, age 72, unknown 235.6
2849 Male, age 72, unknown 210.5
1848 Female, age 42, unknown 199.1
1890 Male, age 53, unknown 188.8
Median raphe nucleus
nTPM: 266.4
2220 Male, age 76, midline 266.4
Periaquaductal grey, anterior
nTPM: 285.0
1947 Male, age 18, unknown 300.9
1795 Male, age 51, unknown 289.4
2502 Female, age 75, unknown 264.6
Periaquaductal grey, dorsal
nTPM: 211.5
1840 Male, age 53, unknown 286.6
2464 Female, age 72, unknown 190.9
2850 Male, age 76, both hemispheres 188.3
1831 Male, age 72, unknown 180.2
Periaquaductal grey, lateral
nTPM: 188.4
2053 Male, age 18, unknown 220.5
2140 Male, age 76, both hemispheres 190.4
2272 Male, age 74, both hemispheres 154.2
Pretectal area
nTPM: 238.5
1816 Male, age 51, unknown 288.4
2007 Male, age 72, unknown 279.3
2667 Female, age 75, unknown 270.6
2224 Female, age 72, unknown 259.5
1817 Female, age 42, unknown 250.8
2825 Male, age 18, unknown 249.1
1944 Female, age 72, unknown 240.3
1815 Male, age 53, unknown 227.5
2407 Male, age 75, both hemispheres 192.9
2273 Male, age 74, both hemispheres 183.6
2316 Male, age 76, right hemisphere 181.8
Red nucleus
nTPM: 194.9
1821 Female, age 72, unknown 242.7
2584 Male, age 75, left hemisphere 240.5
2725 Female, age 75, unknown 198.5
2769 Male, age 72, unknown 197.5
2588 Male, age 74, left hemisphere 196.9
2227 Male, age 72, unknown 196.7
2503 Female, age 72, unknown 191.4
2785 Male, age 18, unknown 189.7
1954 Female, age 42, unknown 186.9
1904 Male, age 53, unknown 185.0
1865 Male, age 51, unknown 162.0
2823 Male, age 76, right hemisphere 151.2
Substantia nigra
nTPM: 248.2
1916 Female, age 42, unknown 302.3
1851 Male, age 51, unknown 284.8
2665 Male, age 74, both hemispheres 267.8
2241 Male, age 72, unknown 262.0
2583 Male, age 75, right hemisphere 260.6
1889 Female, age 72, unknown 258.0
1941 Male, age 53, unknown 248.3
2409 Female, age 72, unknown 209.9
2590 Female, age 75, unknown 197.2
2699 Male, age 18, unknown 191.3
Superior colliculus
nTPM: 223.9
2664 Male, age 75, both hemispheres 290.2
2261 Male, age 18, unknown 260.8
1796 Male, age 53, unknown 259.6
2668 Female, age 75, unknown 250.1
1839 Male, age 51, unknown 227.5
2087 Female, age 72, unknown 220.1
1895 Male, age 76, right hemisphere 203.9
2587 Male, age 74, left hemisphere 193.2
1913 Female, age 42, unknown 182.8
1995 Male, age 72, unknown 150.7
Ventral tegmental area
nTPM: 247.8
2410 Female, age 72, unknown 284.4
1915 Female, age 42, unknown 278.3
1942 Male, age 51, unknown 243.7
2223 Female, age 72, unknown 235.9
2021 Male, age 53, unknown 222.4
2218 Male, age 76, both hemispheres 222.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

232.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 232.4
Samples: 139

Max nTPM: 393.0
Min nTPM: 141.9
Std nTPM: 49.9
Median nTPM: 223.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 393.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 369.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 351.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 351.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 348.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 341.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 321.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 319.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 315.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 314.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 313.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 312.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 307.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 302.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 301.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 300.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 299.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 299.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 297.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 292.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 290.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 289.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 287.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 283.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 282.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 280.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 276.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 276.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 275.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 273.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 273.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 270.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 269.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 261.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 261.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 261.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 260.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 257.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 255.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 254.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 253.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 252.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 250.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 249.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 245.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 244.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 243.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 241.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 241.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 240.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 240.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 240.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 238.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 237.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 236.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 235.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 234.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 234.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 233.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 231.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 228.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 228.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 228.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 227.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 226.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 226.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 225.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 225.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 224.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 223.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 223.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 220.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 219.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 219.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 218.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 218.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 218.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 218.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 216.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 216.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 216.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 214.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 213.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 212.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 212.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 212.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 211.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 211.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 209.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 207.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 206.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 206.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 205.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 204.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 203.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 203.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 203.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 201.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 199.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 198.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 198.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 197.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 197.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 196.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 194.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 191.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 190.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 188.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 188.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 187.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 187.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 187.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 186.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 186.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 184.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 183.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 182.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 182.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 182.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 182.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 181.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 181.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 179.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 179.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 179.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 178.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 178.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 177.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 175.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 173.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 172.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 167.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 162.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 159.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 157.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 157.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 154.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 146.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 141.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

157.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 157.9
FF:10158-103A5 76 years, female 157.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

220.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 220.6
Samples: 4

Max nTPM: 315.6
Min nTPM: 120.8
Sample A Female 315.6
Sample B Female 178.6
Sample C Male 267.4
Sample D Male 120.8
Midbrain
nTPM: 216.6
Samples: 4

Max nTPM: 265.0
Min nTPM: 179.2
Sample A Female 210.2
Sample B Female 179.2
Sample C Male 265.0
Sample D Male 211.9
Periaqueductal gray
nTPM: 180.2
Samples: 3

Max nTPM: 217.7
Min nTPM: 157.7
Sample B Female 165.2
Sample C Male 217.7
Sample D Male 157.7
Superior colliculi
nTPM: 215.7
Samples: 4

Max nTPM: 261.6
Min nTPM: 191.4
Sample A Female 261.6
Sample B Female 204.9
Sample C Male 204.8
Sample D Male 191.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

431.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 431.7
Samples: 4

Max nTPM: 442.0
Min nTPM: 419.3
Sample A Male 436.1
Sample B Male 429.2
Sample C Female 419.3
Sample D Female 442.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

15.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 15.9
67764936 Antisense, RP_040916_02_F04, Mouse strain C57BL/6J (56 days, male) 15.9

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