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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:99.0 nTPM
HPA Brain:362.3 nTPM
GTEx:99.0 nTPM
FANTOM5:83.0 Scaled Tags Per Million
Pig:136.9 nTPM
Mouse:113.3 nTPM
Allen mouse:6.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

362.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 140.5
2411 Female, age 72, unknown 178.5
1827 Male, age 72, unknown 176.5
2219 Male, age 76, both hemispheres 165.9
1870 Female, age 42, unknown 152.9
1833 Male, age 53, unknown 150.7
2666 Male, age 74, left hemisphere 148.7
2586 Male, age 75, left hemisphere 147.1
2828 Female, age 72, unknown 140.8
1830 Male, age 51, unknown 127.3
2019 Male, age 18, unknown 17.3
Dorsal raphe nucleus
nTPM: 217.2
2298 Female, age 72, unknown 316.6
2047 Male, age 72, unknown 232.0
2750 Male, age 76, both hemispheres 201.0
1828 Male, age 53, unknown 169.6
2016 Female, age 72, unknown 166.7
Inferior colliculus
nTPM: 136.9
2849 Male, age 72, unknown 178.8
2097 Female, age 72, unknown 145.1
1848 Female, age 42, unknown 119.4
1890 Male, age 53, unknown 104.3
Median raphe nucleus
nTPM: 362.3
2220 Male, age 76, midline 362.3
Periaquaductal grey, anterior
nTPM: 285.0
2502 Female, age 75, unknown 299.7
1795 Male, age 51, unknown 280.1
1947 Male, age 18, unknown 275.0
Periaquaductal grey, dorsal
nTPM: 256.2
1840 Male, age 53, unknown 338.6
2850 Male, age 76, both hemispheres 304.5
1831 Male, age 72, unknown 208.3
2464 Female, age 72, unknown 173.6
Periaquaductal grey, lateral
nTPM: 298.5
2053 Male, age 18, unknown 458.4
2140 Male, age 76, both hemispheres 262.5
2272 Male, age 74, both hemispheres 174.6
Pretectal area
nTPM: 232.2
2825 Male, age 18, unknown 454.1
2224 Female, age 72, unknown 288.7
2407 Male, age 75, both hemispheres 250.3
1816 Male, age 51, unknown 247.2
1815 Male, age 53, unknown 238.9
2667 Female, age 75, unknown 228.3
2273 Male, age 74, both hemispheres 211.8
1817 Female, age 42, unknown 166.9
1944 Female, age 72, unknown 164.1
2316 Male, age 76, right hemisphere 163.5
2007 Male, age 72, unknown 140.2
Red nucleus
nTPM: 45.3
2584 Male, age 75, left hemisphere 149.6
2725 Female, age 75, unknown 78.4
2588 Male, age 74, left hemisphere 68.4
2227 Male, age 72, unknown 38.7
2769 Male, age 72, unknown 38.3
2503 Female, age 72, unknown 34.9
1821 Female, age 72, unknown 27.3
1954 Female, age 42, unknown 22.6
2823 Male, age 76, right hemisphere 22.5
1904 Male, age 53, unknown 21.4
1865 Male, age 51, unknown 20.7
2785 Male, age 18, unknown 20.6
Substantia nigra
nTPM: 130.3
2699 Male, age 18, unknown 229.5
1889 Female, age 72, unknown 148.8
2665 Male, age 74, both hemispheres 142.8
1851 Male, age 51, unknown 131.6
2241 Male, age 72, unknown 129.3
1941 Male, age 53, unknown 115.4
2583 Male, age 75, right hemisphere 113.9
2590 Female, age 75, unknown 103.7
1916 Female, age 42, unknown 98.3
2409 Female, age 72, unknown 89.7
Superior colliculus
nTPM: 190.5
2261 Male, age 18, unknown 350.8
2664 Male, age 75, both hemispheres 275.1
1796 Male, age 53, unknown 234.4
1839 Male, age 51, unknown 205.8
2587 Male, age 74, left hemisphere 190.4
1913 Female, age 42, unknown 149.6
2087 Female, age 72, unknown 146.1
1995 Male, age 72, unknown 138.3
1895 Male, age 76, right hemisphere 122.2
2668 Female, age 75, unknown 92.5
Ventral tegmental area
nTPM: 178.6
1942 Male, age 51, unknown 219.0
2021 Male, age 53, unknown 212.2
2223 Female, age 72, unknown 186.1
2218 Male, age 76, both hemispheres 183.2
1915 Female, age 42, unknown 163.6
2410 Female, age 72, unknown 107.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

99.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 99.0
Samples: 139

Max nTPM: 236.6
Min nTPM: 31.9
Std nTPM: 40.6
Median nTPM: 91.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 236.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 221.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 213.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 213.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 190.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 177.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 175.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 171.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 167.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 166.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 161.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 159.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 159.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 158.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 155.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 155.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 150.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 148.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 146.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 142.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 137.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 136.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 136.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 136.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 133.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 132.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 131.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 131.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 128.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 127.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 124.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 124.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 123.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 123.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 122.3
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 120.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 119.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 117.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 115.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 115.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 114.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 114.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 113.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 112.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 112.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 111.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 111.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 109.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 109.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 108.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 107.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 106.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 105.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 103.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 102.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 101.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 101.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 100.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 100.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 99.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 99.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 98.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 97.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 97.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 95.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 94.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 94.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 92.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 91.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 91.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 91.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 90.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 90.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 90.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 89.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 89.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 88.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 88.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 86.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 86.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 86.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 84.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 84.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 83.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 83.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 83.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 82.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 81.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 81.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 80.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 79.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 79.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 79.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 76.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 76.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 76.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 75.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 75.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 71.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 70.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 70.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 69.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 69.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 69.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 68.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 67.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 67.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 67.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 65.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 65.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 65.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 63.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 63.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 62.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 61.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 58.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 58.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 56.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 56.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 54.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 54.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 53.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 52.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 52.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 51.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 51.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 51.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 49.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 49.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 49.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 48.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 48.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 45.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 44.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 42.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 41.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 37.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 37.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 31.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

83.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 83.0
FF:10158-103A5 76 years, female 83.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

136.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 136.9
Samples: 4

Max nTPM: 177.5
Min nTPM: 68.3
Sample A Female 153.0
Sample B Female 148.8
Sample C Male 177.5
Sample D Male 68.3
Midbrain
nTPM: 124.0
Samples: 4

Max nTPM: 155.9
Min nTPM: 97.1
Sample A Female 97.1
Sample B Female 112.1
Sample C Male 155.9
Sample D Male 130.7
Periaqueductal gray
nTPM: 126.5
Samples: 3

Max nTPM: 167.0
Min nTPM: 101.9
Sample B Female 101.9
Sample C Male 167.0
Sample D Male 110.5
Superior colliculi
nTPM: 83.9
Samples: 4

Max nTPM: 106.9
Min nTPM: 64.4
Sample A Female 106.9
Sample B Female 67.1
Sample C Male 64.4
Sample D Male 97.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

113.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 113.3
Samples: 4

Max nTPM: 121.9
Min nTPM: 103.1
Sample A Male 114.2
Sample B Male 114.1
Sample C Female 103.1
Sample D Female 121.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

6.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 6.0
69113656 Antisense, RP_050316_02_E05, Mouse strain C57BL/6J (56 days, male) 7.1
73592534 Antisense, RP_051017_01_E10, Mouse strain C57BL/6J (56 days, male) 4.8

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