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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:1263.2 nTPM
HPA Brain:424.8 nTPM
GTEx:1263.2 nTPM
FANTOM5:403.2 Scaled Tags Per Million
Pig:3.0 nTPM
Mouse:788.3 nTPM
Allen mouse:4.0 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

424.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 338.2
2586 Male, age 75, left hemisphere 384.6
2411 Female, age 72, unknown 380.3
2828 Female, age 72, unknown 353.6
2219 Male, age 76, both hemispheres 351.4
1870 Female, age 42, unknown 347.9
2019 Male, age 18, unknown 344.5
2666 Male, age 74, left hemisphere 336.8
1830 Male, age 51, unknown 306.1
1833 Male, age 53, unknown 298.2
1827 Male, age 72, unknown 279.1
Dorsal raphe nucleus
nTPM: 337.4
2750 Male, age 76, both hemispheres 371.9
2016 Female, age 72, unknown 347.6
2298 Female, age 72, unknown 336.6
1828 Male, age 53, unknown 322.0
2047 Male, age 72, unknown 308.9
Inferior colliculus
nTPM: 313.3
1890 Male, age 53, unknown 351.2
1848 Female, age 42, unknown 304.3
2097 Female, age 72, unknown 300.7
2849 Male, age 72, unknown 297.2
Median raphe nucleus
nTPM: 363.3
2220 Male, age 76, midline 363.3
Periaquaductal grey, anterior
nTPM: 424.8
2502 Female, age 75, unknown 527.6
1795 Male, age 51, unknown 422.1
1947 Male, age 18, unknown 324.7
Periaquaductal grey, dorsal
nTPM: 318.3
2464 Female, age 72, unknown 358.3
1840 Male, age 53, unknown 357.1
2850 Male, age 76, both hemispheres 292.3
1831 Male, age 72, unknown 265.4
Periaquaductal grey, lateral
nTPM: 329.8
2140 Male, age 76, both hemispheres 333.9
2053 Male, age 18, unknown 329.1
2272 Male, age 74, both hemispheres 326.4
Pretectal area
nTPM: 302.4
2007 Male, age 72, unknown 332.5
2273 Male, age 74, both hemispheres 327.6
2316 Male, age 76, right hemisphere 325.3
2825 Male, age 18, unknown 306.9
2224 Female, age 72, unknown 305.2
1815 Male, age 53, unknown 302.8
2407 Male, age 75, both hemispheres 298.8
1817 Female, age 42, unknown 295.0
1816 Male, age 51, unknown 291.7
1944 Female, age 72, unknown 276.4
2667 Female, age 75, unknown 263.9
Red nucleus
nTPM: 372.7
2503 Female, age 72, unknown 521.4
2227 Male, age 72, unknown 450.8
2769 Male, age 72, unknown 417.1
1865 Male, age 51, unknown 406.4
1904 Male, age 53, unknown 379.7
2588 Male, age 74, left hemisphere 362.1
2725 Female, age 75, unknown 356.1
2584 Male, age 75, left hemisphere 353.9
2785 Male, age 18, unknown 346.1
1954 Female, age 42, unknown 304.2
1821 Female, age 72, unknown 301.3
2823 Male, age 76, right hemisphere 273.4
Substantia nigra
nTPM: 411.9
2409 Female, age 72, unknown 532.0
1851 Male, age 51, unknown 521.2
2699 Male, age 18, unknown 499.2
1916 Female, age 42, unknown 473.9
2590 Female, age 75, unknown 382.1
2665 Male, age 74, both hemispheres 378.9
1941 Male, age 53, unknown 348.6
2241 Male, age 72, unknown 347.4
2583 Male, age 75, right hemisphere 321.6
1889 Female, age 72, unknown 314.5
Superior colliculus
nTPM: 341.2
1995 Male, age 72, unknown 416.6
1913 Female, age 42, unknown 410.9
2587 Male, age 74, left hemisphere 402.9
1796 Male, age 53, unknown 365.0
2261 Male, age 18, unknown 355.0
2668 Female, age 75, unknown 329.5
2087 Female, age 72, unknown 327.4
2664 Male, age 75, both hemispheres 306.2
1839 Male, age 51, unknown 296.1
1895 Male, age 76, right hemisphere 202.2
Ventral tegmental area
nTPM: 408.5
1915 Female, age 42, unknown 466.1
2223 Female, age 72, unknown 465.7
2410 Female, age 72, unknown 438.1
2021 Male, age 53, unknown 385.6
1942 Male, age 51, unknown 360.4
2218 Male, age 76, both hemispheres 335.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1263.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 1263.2
Samples: 139

Max nTPM: 5097.9
Min nTPM: 378.5
Std nTPM: 545.6
Median nTPM: 1160.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 5097.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 2860.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 2741.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 2656.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 2656.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 1988.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 1956.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1940.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1937.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 1871.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 1870.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1838.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1828.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1814.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1791.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1730.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1708.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 1690.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1688.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1668.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 1661.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1660.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1643.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1638.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1635.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 1610.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1606.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 1573.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 1569.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1547.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 1540.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1532.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1505.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 1486.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 1473.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 1462.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 1461.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1445.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1440.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 1437.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1428.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 1424.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1418.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 1417.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 1413.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1412.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 1404.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1393.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 1388.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1358.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 1311.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1310.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 1310.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1309.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 1297.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 1259.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 1247.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1242.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 1238.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 1228.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 1226.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 1220.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 1214.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1208.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1199.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1168.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 1165.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1161.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 1161.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 1160.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 1151.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 1151.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 1141.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1134.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 1126.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 1126.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 1116.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 1113.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 1111.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 1109.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 1107.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 1106.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 1098.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 1094.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 1086.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 1077.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 1061.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 1055.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 1051.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 1049.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 1041.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 1039.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 1039.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 1033.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 1026.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 1022.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 1020.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 1015.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 1010.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 1006.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 994.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 964.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 960.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 959.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 914.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 911.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 907.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 907.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 898.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 896.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 893.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 873.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 872.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 865.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 863.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 861.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 860.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 856.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 840.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 835.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 809.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 802.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 795.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 791.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 778.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 745.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 735.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 694.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 642.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 635.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 631.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 618.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 592.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 591.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 581.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 557.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 495.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 478.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 378.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

403.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 403.2
FF:10158-103A5 76 years, female 403.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

3.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 3.0
Samples: 4

Max nTPM: 4.5
Min nTPM: 1.4
Sample A Female 1.4
Sample B Female 3.0
Sample C Male 3.1
Sample D Male 4.5
Midbrain
nTPM: 1.7
Samples: 4

Max nTPM: 3.6
Min nTPM: 0.5
Sample A Female 0.5
Sample B Female 2.1
Sample C Male 0.5
Sample D Male 3.6
Periaqueductal gray
nTPM: 2.3
Samples: 3

Max nTPM: 3.9
Min nTPM: 1.4
Sample B Female 1.6
Sample C Male 1.4
Sample D Male 3.9
Superior colliculi
nTPM: 2.3
Samples: 4

Max nTPM: 3.1
Min nTPM: 1.7
Sample A Female 1.7
Sample B Female 2.3
Sample C Male 2.0
Sample D Male 3.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

788.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 788.3
Samples: 4

Max nTPM: 1053.4
Min nTPM: 615.0
Sample A Male 1053.4
Sample B Male 699.5
Sample C Female 615.0
Sample D Female 785.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

4.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.0
69818344 Antisense, RP_050510_04_H07, Mouse strain C57BL/6J (56 days, male) 4.0

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