Expression of RPS24 in urothelial cancer

BLADDER UROTHELIAL CARCINOMA (TCGA) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

RPS24 is not prognostic in Bladder Urothelial Carcinoma (TCGA)

Stage:

Survival analysis

Current cut offⁱ :

Best expression cut offⁱ : 1668.43

Median expressionⁱ : N/A

Median follow up timeⁱ : N/A

P scoreⁱ N/A

5-year survival highⁱ N/A

5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average pTPM

2695.4

Number of samples

169

Samples

Sample	Description	pTPM
TCGA-XF-AAMH-01A	80 years, male, white, stage:Stage IV, dead, 344 days	8171.1
TCGA-BT-A0S7-01A	75 years, male, white, stage:Stage III, dead, 200 days	7487.2
TCGA-UY-A78N-01A	80 years, male, white, stage:Stage IV, dead, 2641 days	6873.5
TCGA-G2-A2EC-01A	58 years, female, black or african american, stage:Stage II, dead, 696 days	6075.3
TCGA-UY-A78M-01A	81 years, female, asian, stage:Stage IV, dead, 690 days	5925.0
TCGA-XF-AAN1-01A	75 years, female, stage:Stage III, dead, 941 days	5798.0
TCGA-E7-A4XJ-01A	66 years, male, asian, stage:Stage II, dead, 68 days	5606.5
TCGA-DK-A1A3-01A	60 years, male, white, stage:Stage IV, dead, 665 days	5212.0
TCGA-XF-AAN8-01A	74 years, female, white, stage:Stage III, dead, 118 days	5078.9
TCGA-BT-A20J-01A	75 years, male, white, stage:Stage II, dead, 579 days	4990.2
TCGA-G2-A2EO-01A	69 years, male, white, stage:Stage III, dead, 1804 days	4898.8
TCGA-BT-A20W-01A	71 years, male, white, stage:Stage II, dead, 254 days	4896.6
TCGA-ZF-AA5N-01A	62 years, female, white, stage:Stage IV, dead, 168 days	4884.3
TCGA-XF-A9SH-01A	65 years, female, asian, stage:Stage II, dead, 1971 days	4843.0
TCGA-BT-A3PK-01A	80 years, male, white, stage:Stage II, dead, 303 days	4772.2
TCGA-HQ-A5ND-01A	78 years, male, stage:Stage IV, dead, 274 days	4756.0
TCGA-FD-A5BV-01A	47 years, female, white, stage:Stage III, dead, 163 days	4588.5
TCGA-CF-A47T-01A	58 years, female, asian, stage:Stage II, dead, 385 days	4502.0
TCGA-ZF-AA4N-01A	74 years, male, white, stage:Stage II, dead, 88 days	4497.3
TCGA-XF-A8HI-01A	57 years, female, white, stage:Stage IV, dead, 544 days	4400.9
TCGA-DK-AA6Q-01A	61 years, female, white, stage:Stage IV, dead, 413 days	4368.4
TCGA-5N-A9KM-01A	73 years, female, white, stage:Stage III, dead, 530 days	4331.0
TCGA-FD-A62O-01A	74 years, male, white, stage:Stage IV, dead, 216 days	4320.8
TCGA-BT-A3PH-01A	76 years, male, white, stage:Stage IV, dead, 142 days	4294.9
TCGA-FD-A5BX-01A	82 years, male, white, stage:Stage IV, dead, 173 days	4235.2
TCGA-C4-A0EZ-01A	69 years, female, stage:Stage IV, dead, 273 days	4233.4
TCGA-XF-AAN2-01A	73 years, male, white, stage:Stage II, dead, 1869 days	4214.8
TCGA-FD-A43Y-01A	65 years, male, white, stage:Stage III, dead, 474 days	4081.7
TCGA-G2-A2ES-01A	85 years, male, white, stage:Stage II, dead, 1004 days	4061.3
TCGA-XF-A8HG-01A	69 years, male, white, stage:Stage III, dead, 467 days	4000.2
TCGA-FD-A3B6-01A	75 years, male, white, stage:Stage II, dead, 1005 days	3998.6
TCGA-ZF-A9RN-01A	67 years, female, white, stage:Stage III, dead, 615 days	3959.0
TCGA-FD-A3B4-01A	55 years, female, black or african american, stage:Stage III, dead, 510 days	3892.0
TCGA-XF-AAN0-01A	68 years, male, white, stage:Stage IV, dead, 1718 days	3882.2
TCGA-4Z-AA7N-01A	65 years, male, white, stage:Stage III, dead, 1367 days	3778.6
TCGA-C4-A0F7-01A	77 years, male, stage:Stage IV, dead, 62 days	3777.4
TCGA-ZF-A9R0-01A	82 years, male, white, stage:Stage III, dead, 680 days	3770.0
TCGA-E5-A4TZ-01A	64 years, male, white, stage:Stage IV, dead, 467 days	3751.6
TCGA-DK-AA75-01A	82 years, male, white, stage:Stage III, dead, 340 days	3725.8
TCGA-FD-A3N5-01A	69 years, male, black or african american, stage:Stage II, dead, 685 days	3707.5
TCGA-FD-A6TH-01A	63 years, male, white, stage:Stage IV, dead, 131 days	3702.5
TCGA-FD-A3SJ-01A	59 years, male, white, stage:Stage IV, dead, 739 days	3631.7
TCGA-XF-A8HF-01A	80 years, male, white, stage:Stage III, dead, 2954 days	3629.3
TCGA-ZF-AA54-01A	71 years, male, white, stage:Stage III, dead, 590 days	3629.0
TCGA-FJ-A871-01A	49 years, male, white, stage:Stage III, dead, 272 days	3565.5
TCGA-K4-A5RI-01A	67 years, female, white, stage:Stage III, dead, 356 days	3564.0
TCGA-ZF-AA56-01A	79 years, female, white, stage:Stage III, dead, 259 days	3562.1
TCGA-BT-A20N-01A	72 years, male, stage:Stage III, dead, 795 days	3516.0
TCGA-2F-A9KP-01A	66 years, male, white, stage:Stage IV, dead, 364 days	3492.6
TCGA-GV-A3JV-01A	66 years, male, white, stage:Stage IV, dead, 434 days	3479.8
TCGA-GU-AATO-01A	75 years, male, white, stage:Stage IV, dead, 324 days	3479.3
TCGA-XF-A8HC-01A	79 years, male, asian, stage:Stage IV, dead, 200 days	3471.6
TCGA-DK-A1AB-01A	74 years, female, white, stage:Stage IV, dead, 508 days	3440.6
TCGA-BL-A13J-01A	65 years, male, white, stage:Stage IV, dead, 81 days	3417.3
TCGA-GU-A762-01A	87 years, male, white, stage:Stage IV, dead, 232 days	3395.4
TCGA-FJ-A3Z9-01A	72 years, male, white, stage:'--, dead, 385 days	3350.2
TCGA-FD-A6TG-01A	73 years, male, white, stage:Stage IV, dead, 93 days	3326.5
TCGA-ZF-A9R3-01A	53 years, female, white, stage:Stage II, dead, 949 days	3324.4
TCGA-G2-A2EL-01A	77 years, male, white, stage:Stage II, dead, 819 days	3309.7
TCGA-CU-A0YO-01A	84 years, male, white, stage:Stage IV, dead, 149 days	3289.0
TCGA-CU-A72E-01A	76 years, male, white, stage:Stage IV, dead, 413 days	3114.3
TCGA-FD-A3SQ-01A	62 years, male, white, stage:Stage IV, dead, 1423 days	3112.9
TCGA-XF-A9SZ-01A	79 years, male, white, stage:Stage IV, dead, 859 days	3112.0
TCGA-XF-A9SK-01A	65 years, male, white, stage:Stage IV, dead, 486 days	3097.0
TCGA-BT-A20X-01A	56 years, male, white, stage:Stage IV, dead, 251 days	3082.1
TCGA-DK-AA6W-01A	78 years, male, white, stage:Stage II, dead, 415 days	3080.4
TCGA-BT-A20V-01A	59 years, female, black or african american, stage:Stage IV, dead, 154 days	3062.1
TCGA-E7-A97P-01A	73 years, male, asian, stage:Stage II, dead, 437 days	3052.1
TCGA-FJ-A3ZE-01A	65 years, male, white, stage:Stage IV, dead, 324 days	3051.1
TCGA-XF-AAN7-01A	60 years, male, white, stage:Stage IV, dead, 565 days	3031.7
TCGA-FD-A6TF-01A	80 years, female, white, stage:Stage IV, dead, 69 days	3026.5
TCGA-XF-A8HH-01A	61 years, female, white, stage:Stage IV, dead, 57 days	2970.9
TCGA-GU-A42Q-01A	67 years, male, white, stage:Stage III, dead, 344 days	2892.3
TCGA-FD-A5C0-01A	61 years, male, white, stage:Stage IV, dead, 550 days	2875.2
TCGA-GU-A42R-01A	68 years, male, white, stage:Stage IV, dead, 577 days	2866.0
TCGA-DK-A3IQ-01A	74 years, male, white, stage:Stage III, dead, 539 days	2826.6
TCGA-2F-A9KO-01A	63 years, male, white, stage:Stage IV, dead, 734 days	2816.5
TCGA-4Z-AA7Q-01A	79 years, male, white, stage:Stage III, dead, 510 days	2816.5
TCGA-UY-A78K-01A	60 years, male, white, stage:Stage IV, dead, 536 days	2790.9
TCGA-XF-A9ST-01A	68 years, male, white, stage:Stage III, dead, 128 days	2743.1
TCGA-ZF-A9RD-01A	75 years, female, white, stage:Stage IV, dead, 408 days	2715.9
TCGA-BT-A20Q-01A	73 years, male, white, stage:Stage IV, dead, 593 days	2669.6
TCGA-FD-A6TI-01A	73 years, male, white, stage:Stage IV, dead, 294 days	2640.0
TCGA-2F-A9KW-01A	67 years, female, white, stage:Stage III, dead, 254 days	2601.4
TCGA-FD-A3SS-01A	66 years, male, white, stage:Stage IV, dead, 391 days	2600.7
TCGA-4Z-AA82-01A	59 years, male, black or african american, stage:Stage IV, dead, 1556 days	2594.2
TCGA-DK-A2I2-01A	63 years, female, white, stage:Stage IV, dead, 237 days	2584.4
TCGA-GC-A3BM-01A	70 years, male, white, stage:Stage II, dead, 651 days	2566.3
TCGA-5N-A9KI-01A	76 years, female, white, stage:Stage III, dead, 76 days	2557.7
TCGA-FD-A62P-01A	76 years, male, white, stage:Stage II, dead, 191 days	2541.6
TCGA-BT-A0YX-01A	70 years, female, white, stage:Stage III, dead, 400 days	2467.6
TCGA-DK-A3IU-01A	58 years, male, white, stage:Stage II, dead, 706 days	2455.1
TCGA-XF-A9SP-01A	59 years, male, white, stage:Stage III, dead, 454 days	2434.5
TCGA-4Z-AA86-01A	66 years, male, black or african american, stage:Stage IV, dead, 311 days	2423.8
TCGA-GU-AATQ-01A	68 years, male, white, stage:Stage III, dead, 213 days	2413.9
TCGA-BT-A2LB-01A	73 years, female, white, stage:Stage III, dead, 492 days	2335.1
TCGA-HQ-A5NE-01A	57 years, male, stage:Stage III, dead, 370 days	2318.5
TCGA-XF-AAMW-01A	79 years, female, white, stage:Stage IV, dead, 253 days	2275.3
TCGA-CF-A9FL-01A	85 years, male, asian, stage:Stage III, dead, 565 days	2251.4
TCGA-CU-A0YR-01A	83 years, male, white, stage:Stage IV, dead, 460 days	2207.3
TCGA-FD-A3B3-01A	74 years, female, white, stage:Stage III, dead, 974 days	2195.6
TCGA-CU-A5W6-01A	70 years, male, white, stage:Stage III, dead, 56 days	2158.0
TCGA-GV-A3QH-01A	67 years, male, white, stage:Stage II, dead, 258 days	2116.0
TCGA-FD-A3SM-01A	70 years, male, white, stage:Stage IV, dead, 547 days	2104.6
TCGA-XF-A9SW-01A	85 years, male, white, stage:Stage IV, dead, 362 days	2078.8
TCGA-FD-A6TD-01A	77 years, male, white, stage:Stage III, dead, 386 days	2073.0
TCGA-CU-A0YN-01A	60 years, male, white, stage:Stage III, dead, 393 days	2011.2
TCGA-ZF-AA4U-01A	70 years, male, white, stage:Stage III, dead, 262 days	1928.2
TCGA-DK-A3IK-01A	87 years, male, white, stage:Stage IV, dead, 146 days	1901.7
TCGA-G2-A3IB-01A	66 years, male, black or african american, stage:Stage II, dead, 220 days	1881.2
TCGA-XF-AAMT-01A	75 years, female, white, stage:Stage IV, dead, 90 days	1871.9
TCGA-FD-A3B5-01A	86 years, male, black or african american, stage:Stage IV, dead, 272 days	1867.9
TCGA-4Z-AA7R-01A	73 years, male, black or african american, stage:Stage IV, dead, 522 days	1858.5
TCGA-FD-A3B7-01A	66 years, male, black or african american, stage:Stage III, dead, 122 days	1841.2
TCGA-GU-A767-01A	81 years, male, white, stage:Stage IV, dead, 144 days	1810.4
TCGA-XF-AAML-01A	75 years, male, white, stage:Stage II, dead, 232 days	1781.0
TCGA-YC-A9TC-01A	71 years, male, white, stage:Stage IV, dead, 20 days	1725.9
TCGA-XF-A9T2-01A	54 years, male, white, stage:Stage III, dead, 575 days	1722.0
TCGA-G2-AA3C-01A	66 years, male, white, stage:Stage IV, dead, 211 days	1668.4
TCGA-4Z-AA7S-01A	66 years, male, black or african american, stage:Stage III, dead, 1064 days	1643.5
TCGA-FD-A5BT-01A	84 years, male, white, stage:Stage III, dead, 328 days	1632.3
TCGA-XF-A9SL-01A	69 years, male, white, stage:Stage IV, dead, 2020 days	1620.4
TCGA-BL-A3JM-01A	62 years, male, white, stage:Stage III, dead, 205 days	1609.9
TCGA-XF-AAN4-01A	77 years, female, white, stage:Stage III, dead, 823 days	1597.9
TCGA-K4-A4AC-01A	83 years, male, white, stage:Stage II, dead, 278 days	1596.8
TCGA-SY-A9G0-01A	82 years, male, white, stage:Stage IV, dead, 1008 days	1594.3
TCGA-GV-A3QF-01A	79 years, male, white, stage:Stage IV, dead, 617 days	1555.6
TCGA-DK-A1A5-01A	79 years, male, white, stage:Stage II, dead, 65 days	1465.3
TCGA-BT-A2LD-01A	78 years, female, white, stage:Stage IV, dead, 623 days	1453.7
TCGA-XF-A9SX-01A	63 years, female, white, stage:Stage IV, dead, 719 days	1289.1
TCGA-ZF-A9R9-01A	58 years, male, white, stage:Stage IV, dead, 864 days	1242.6
TCGA-FD-A3SO-01A	68 years, male, white, stage:Stage IV, dead, 168 days	1237.4
TCGA-XF-A9SJ-01A	83 years, male, white, stage:Stage IV, dead, 98 days	1234.6
TCGA-XF-AAME-01A	64 years, female, white, stage:Stage II, dead, 2828 days	1218.2
TCGA-E7-A3X6-01A	70 years, male, white, stage:Stage II, dead, 904 days	1215.3
TCGA-FD-A3SL-01A	60 years, male, white, stage:Stage IV, dead, 712 days	1160.4
TCGA-BT-A20U-01A	70 years, female, white, stage:Stage III, dead, 455 days	1156.8
TCGA-G2-A3IE-01A	51 years, male, white, stage:Stage II, dead, 612 days	1152.7
TCGA-XF-AAMZ-01A	81 years, female, white, stage:Stage IV, dead, 1348 days	1119.9
TCGA-4Z-AA80-01A	73 years, male, white, stage:Stage II, dead, 19 days	1105.4
TCGA-XF-A9T8-01A	64 years, male, white, stage:Stage III, dead, 418 days	1096.4
TCGA-DK-A3IL-01A	79 years, female, white, stage:Stage IV, dead, 413 days	1087.0
TCGA-BL-A13I-01A	57 years, female, white, stage:Stage III, dead, 223 days	1070.2
TCGA-XF-A9SV-01A	82 years, male, white, stage:Stage IV, dead, 388 days	1060.9
TCGA-ZF-A9RE-01A	78 years, female, white, stage:Stage II, dead, 106 days	1029.1
TCGA-XF-A9SU-01A	74 years, female, white, stage:Stage IV, dead, 182 days	1026.5
TCGA-DK-A3IN-01A	72 years, male, white, stage:Stage III, dead, 250 days	942.6
TCGA-GU-A42P-01A	72 years, male, white, stage:Stage IV, dead, 332 days	920.2
TCGA-DK-A2HX-01A	80 years, female, white, stage:Stage IV, dead, 1420 days	916.5
TCGA-FD-A5BZ-01A	77 years, female, white, stage:Stage IV, dead, 835 days	915.9
TCGA-BT-A20P-01A	81 years, female, white, stage:Stage III, dead, 544 days	898.0
TCGA-ZF-AA52-01A	70 years, male, white, stage:Stage III, dead, 1077 days	855.1
TCGA-BT-A20T-01A	63 years, male, white, stage:Stage IV, dead, 453 days	854.4
TCGA-S5-A6DX-01A	83 years, male, white, stage:Stage IV, dead, 56 days	820.1
TCGA-4Z-AA81-01A	80 years, male, white, stage:Stage II, dead, 1270 days	782.3
TCGA-E7-A541-01A	66 years, male, white, stage:Stage II, dead, 778 days	780.4
TCGA-DK-A3X2-01A	85 years, male, white, stage:Stage IV, dead, 547 days	737.7
TCGA-GC-A3I6-01A	45 years, male, white, stage:Stage III, dead, 630 days	733.7
TCGA-DK-A3IM-01A	76 years, male, white, stage:Stage III, dead, 248 days	699.9
TCGA-BT-A20O-01A	75 years, male, white, stage:Stage III, dead, 370 days	688.1
TCGA-GV-A40E-01A	75 years, male, white, stage:Stage II, dead, 261 days	682.7
TCGA-XF-AAMJ-01A	70 years, male, asian, stage:Stage III, dead, 1670 days	646.2
TCGA-FD-A3SR-01A	68 years, male, white, stage:Stage IV, dead, 602 days	643.5
TCGA-XF-AAMX-01A	87 years, female, black or african american, stage:Stage III, dead, 206 days	633.0
TCGA-DK-AA6L-01A	48 years, male, white, stage:Stage IV, dead, 1163 days	586.4
TCGA-ZF-AA4R-01A	67 years, male, white, stage:Stage IV, dead, 1036 days	584.9
TCGA-FD-A62S-01A	60 years, female, black or african american, stage:Stage III, dead, 406 days	452.0
TCGA-ZF-AA4T-01A	65 years, male, white, stage:Stage IV, dead, 599 days	425.7
TCGA-2F-A9KR-01A	59 years, female, stage:Stage III, dead, 3183 days	164.7
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UROTHELIAL CANCER - Protein expressionⁱ A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here. Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

Antibody stainingⁱ Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells. Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.	Antibody HPA003364
Staining
High
Medium
Low
Not detected
Intensity
Strong
Moderate
Weak
Negative
Quantity
>75%
75%-25%
<25%
None
Location
Nuclear
Cytoplasmic/membranous
Cytoplasmic/membranous,nuclear
None
Urothelial carcinoma, High grade
Urothelial carcinoma, Low grade