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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:72.7 nTPM
HPA Brain:219.2 nTPM
GTEx:72.7 nTPM
FANTOM5:218.9 Scaled Tags Per Million
Pig:167.7 nTPM
Mouse:620.1 nTPM
Allen mouse:23.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

219.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 150.0
1827 Male, age 72, unknown 192.4
2586 Male, age 75, left hemisphere 184.3
2666 Male, age 74, left hemisphere 175.9
2411 Female, age 72, unknown 166.3
1870 Female, age 42, unknown 158.9
2219 Male, age 76, both hemispheres 148.1
1833 Male, age 53, unknown 131.9
2828 Female, age 72, unknown 125.4
1830 Male, age 51, unknown 116.6
2019 Male, age 18, unknown 100.3
Dorsal raphe nucleus
nTPM: 194.4
2298 Female, age 72, unknown 277.4
2047 Male, age 72, unknown 224.0
2750 Male, age 76, both hemispheres 171.6
1828 Male, age 53, unknown 167.9
2016 Female, age 72, unknown 130.9
Inferior colliculus
nTPM: 155.5
2097 Female, age 72, unknown 204.2
2849 Male, age 72, unknown 159.0
1848 Female, age 42, unknown 137.7
1890 Male, age 53, unknown 121.3
Median raphe nucleus
nTPM: 219.2
2220 Male, age 76, midline 219.2
Periaquaductal grey, anterior
nTPM: 217.8
2502 Female, age 75, unknown 250.6
1947 Male, age 18, unknown 207.7
1795 Male, age 51, unknown 195.1
Periaquaductal grey, dorsal
nTPM: 166.5
1840 Male, age 53, unknown 208.1
2850 Male, age 76, both hemispheres 171.4
1831 Male, age 72, unknown 152.6
2464 Female, age 72, unknown 133.9
Periaquaductal grey, lateral
nTPM: 168.1
2053 Male, age 18, unknown 174.7
2272 Male, age 74, both hemispheres 173.3
2140 Male, age 76, both hemispheres 156.1
Pretectal area
nTPM: 175.0
2224 Female, age 72, unknown 244.8
1816 Male, age 51, unknown 220.7
1944 Female, age 72, unknown 192.7
2825 Male, age 18, unknown 192.0
2007 Male, age 72, unknown 174.0
2273 Male, age 74, both hemispheres 166.1
1817 Female, age 42, unknown 157.5
2407 Male, age 75, both hemispheres 156.0
1815 Male, age 53, unknown 151.3
2667 Female, age 75, unknown 146.5
2316 Male, age 76, right hemisphere 123.0
Red nucleus
nTPM: 98.3
2584 Male, age 75, left hemisphere 142.3
1821 Female, age 72, unknown 124.5
2725 Female, age 75, unknown 113.8
2785 Male, age 18, unknown 103.9
2769 Male, age 72, unknown 97.1
2588 Male, age 74, left hemisphere 93.7
1954 Female, age 42, unknown 93.0
2227 Male, age 72, unknown 92.7
2503 Female, age 72, unknown 84.8
1904 Male, age 53, unknown 83.7
1865 Male, age 51, unknown 81.7
2823 Male, age 76, right hemisphere 68.8
Substantia nigra
nTPM: 149.8
1916 Female, age 42, unknown 189.7
1941 Male, age 53, unknown 189.0
1889 Female, age 72, unknown 178.2
1851 Male, age 51, unknown 172.2
2241 Male, age 72, unknown 148.9
2583 Male, age 75, right hemisphere 141.7
2699 Male, age 18, unknown 134.1
2590 Female, age 75, unknown 126.6
2665 Male, age 74, both hemispheres 115.1
2409 Female, age 72, unknown 102.0
Superior colliculus
nTPM: 153.3
2261 Male, age 18, unknown 200.8
1796 Male, age 53, unknown 189.2
2664 Male, age 75, both hemispheres 174.6
1839 Male, age 51, unknown 161.2
2087 Female, age 72, unknown 158.7
2668 Female, age 75, unknown 149.8
2587 Male, age 74, left hemisphere 143.9
1895 Male, age 76, right hemisphere 139.5
1913 Female, age 42, unknown 115.0
1995 Male, age 72, unknown 100.3
Ventral tegmental area
nTPM: 176.4
1915 Female, age 42, unknown 180.8
1942 Male, age 51, unknown 180.3
2021 Male, age 53, unknown 176.8
2223 Female, age 72, unknown 175.6
2218 Male, age 76, both hemispheres 174.7
2410 Female, age 72, unknown 170.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

72.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 72.7
Samples: 139

Max nTPM: 403.7
Min nTPM: 7.6
Std nTPM: 67.8
Median nTPM: 48.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 403.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 395.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 250.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 238.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 233.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 225.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 223.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 213.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 207.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 189.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 181.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 173.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 171.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 164.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 162.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 161.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 151.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 150.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 147.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 147.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 142.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 132.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 123.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 122.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 120.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 110.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 102.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 101.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 94.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 93.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 93.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 92.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 92.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 92.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 89.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 89.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 87.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 86.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 85.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 81.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 78.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 78.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 77.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 72.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 71.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 70.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 69.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 67.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 67.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 66.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 65.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 63.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 62.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 62.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 60.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 58.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 57.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 56.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 56.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 55.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 54.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 54.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 53.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 52.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 52.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 51.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 50.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 49.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 49.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 48.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 48.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 48.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 48.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 47.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 47.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 46.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 44.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 44.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 43.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 42.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 42.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 41.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 40.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 39.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 38.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 38.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 37.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 35.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 34.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 34.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 34.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 33.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 33.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 33.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 32.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 32.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 32.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 31.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 31.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 31.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 31.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 30.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 30.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 29.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 29.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 28.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 27.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 26.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 26.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 26.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 25.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 25.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 25.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 24.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 23.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 23.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 23.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 23.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 22.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 22.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 21.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 21.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 21.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 21.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 19.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 19.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 18.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 18.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 18.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 18.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 17.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 17.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 17.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 16.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 15.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 14.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 14.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 14.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 7.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

218.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 218.9
FF:10158-103A5 76 years, female 218.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

167.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 165.8
Samples: 4

Max nTPM: 247.6
Min nTPM: 66.6
Sample A Female 247.6
Sample B Female 120.8
Sample C Male 228.2
Sample D Male 66.6
Midbrain
nTPM: 162.6
Samples: 4

Max nTPM: 222.3
Min nTPM: 95.9
Sample A Female 95.9
Sample B Female 144.3
Sample C Male 187.7
Sample D Male 222.3
Periaqueductal gray
nTPM: 167.7
Samples: 3

Max nTPM: 208.9
Min nTPM: 136.9
Sample B Female 157.4
Sample C Male 208.9
Sample D Male 136.9
Superior colliculi
nTPM: 139.0
Samples: 4

Max nTPM: 195.4
Min nTPM: 70.4
Sample A Female 195.4
Sample B Female 70.4
Sample C Male 138.2
Sample D Male 151.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

620.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 620.1
Samples: 4

Max nTPM: 633.0
Min nTPM: 605.2
Sample A Male 618.9
Sample B Male 623.2
Sample C Female 605.2
Sample D Female 633.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

23.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 23.9
68193013 Antisense, RP_040928_01_C01, Mouse strain C57BL/6J (56 days, male) 23.9
70928293 Antisense, RP_050725_02_C08, Mouse strain C57BL/6J (56 days, male) 23.9

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