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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:45.1 nTPM
HPA Brain:85.6 nTPM
GTEx:45.1 nTPM
FANTOM5:53.8 Scaled Tags Per Million
Pig:57.8 nTPM
Mouse:62.6 nTPM
Allen mouse:2.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

85.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 62.6
2666 Male, age 74, left hemisphere 95.7
2019 Male, age 18, unknown 78.7
2586 Male, age 75, left hemisphere 77.3
1827 Male, age 72, unknown 61.4
1833 Male, age 53, unknown 54.8
2411 Female, age 72, unknown 54.6
1870 Female, age 42, unknown 53.7
2828 Female, age 72, unknown 52.7
1830 Male, age 51, unknown 50.8
2219 Male, age 76, both hemispheres 46.1
Dorsal raphe nucleus
nTPM: 65.9
1828 Male, age 53, unknown 70.6
2047 Male, age 72, unknown 68.9
2750 Male, age 76, both hemispheres 66.7
2298 Female, age 72, unknown 66.3
2016 Female, age 72, unknown 56.8
Inferior colliculus
nTPM: 52.4
1890 Male, age 53, unknown 53.3
2097 Female, age 72, unknown 52.7
2849 Male, age 72, unknown 52.3
1848 Female, age 42, unknown 51.5
Median raphe nucleus
nTPM: 85.6
2220 Male, age 76, midline 85.6
Periaquaductal grey, anterior
nTPM: 61.4
1795 Male, age 51, unknown 63.5
1947 Male, age 18, unknown 62.7
2502 Female, age 75, unknown 58.1
Periaquaductal grey, dorsal
nTPM: 58.4
2850 Male, age 76, both hemispheres 77.6
1831 Male, age 72, unknown 62.1
1840 Male, age 53, unknown 47.8
2464 Female, age 72, unknown 46.3
Periaquaductal grey, lateral
nTPM: 66.3
2272 Male, age 74, both hemispheres 72.1
2140 Male, age 76, both hemispheres 71.8
2053 Male, age 18, unknown 55.1
Pretectal area
nTPM: 65.3
1817 Female, age 42, unknown 82.9
2007 Male, age 72, unknown 82.6
1816 Male, age 51, unknown 79.1
1944 Female, age 72, unknown 77.7
1815 Male, age 53, unknown 72.3
2224 Female, age 72, unknown 60.0
2407 Male, age 75, both hemispheres 57.1
2667 Female, age 75, unknown 55.5
2825 Male, age 18, unknown 54.0
2273 Male, age 74, both hemispheres 52.1
2316 Male, age 76, right hemisphere 44.6
Red nucleus
nTPM: 57.0
1821 Female, age 72, unknown 68.5
2785 Male, age 18, unknown 64.8
2725 Female, age 75, unknown 62.8
1865 Male, age 51, unknown 60.2
2584 Male, age 75, left hemisphere 58.8
2588 Male, age 74, left hemisphere 57.1
2769 Male, age 72, unknown 53.7
1954 Female, age 42, unknown 53.5
2823 Male, age 76, right hemisphere 52.1
1904 Male, age 53, unknown 51.2
2503 Female, age 72, unknown 50.9
2227 Male, age 72, unknown 50.6
Substantia nigra
nTPM: 84.0
1916 Female, age 42, unknown 119.6
1941 Male, age 53, unknown 101.8
1851 Male, age 51, unknown 90.4
2241 Male, age 72, unknown 80.0
2665 Male, age 74, both hemispheres 78.5
2409 Female, age 72, unknown 78.2
2583 Male, age 75, right hemisphere 78.1
1889 Female, age 72, unknown 77.4
2699 Male, age 18, unknown 72.0
2590 Female, age 75, unknown 64.4
Superior colliculus
nTPM: 56.7
2668 Female, age 75, unknown 79.3
2087 Female, age 72, unknown 64.1
2261 Male, age 18, unknown 60.7
1796 Male, age 53, unknown 57.4
2587 Male, age 74, left hemisphere 57.0
1839 Male, age 51, unknown 51.1
1913 Female, age 42, unknown 51.1
2664 Male, age 75, both hemispheres 50.5
1895 Male, age 76, right hemisphere 49.4
1995 Male, age 72, unknown 46.4
Ventral tegmental area
nTPM: 69.3
2218 Male, age 76, both hemispheres 81.7
1915 Female, age 42, unknown 79.8
2410 Female, age 72, unknown 75.7
2021 Male, age 53, unknown 64.8
1942 Male, age 51, unknown 60.7
2223 Female, age 72, unknown 53.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

45.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 45.1
Samples: 139

Max nTPM: 176.8
Min nTPM: 14.6
Std nTPM: 24.9
Median nTPM: 38.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 176.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 143.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 124.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 108.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 103.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 95.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 91.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 90.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 90.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 89.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 83.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 83.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 80.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 80.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 76.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 72.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 71.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 69.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 69.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 68.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 68.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 67.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 67.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 65.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 63.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 60.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 60.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 59.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 57.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 57.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 56.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 56.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 56.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 55.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 53.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 52.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 52.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 51.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 50.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 47.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 46.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 46.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 46.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 45.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 45.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 45.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 44.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 43.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 43.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 43.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 43.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 42.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 42.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 42.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 42.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 41.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 41.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 41.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 41.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 40.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 39.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 39.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 39.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 39.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 39.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 38.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 38.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 38.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 38.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 38.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 38.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 37.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 36.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 36.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 36.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 36.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 36.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 36.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 36.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 35.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 34.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 34.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 34.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 34.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 34.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 33.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 33.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 33.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 33.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 33.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 33.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 33.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 33.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 33.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 33.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 32.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 32.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 31.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 30.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 29.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 29.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 29.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 29.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 29.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 28.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 28.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 28.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 27.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 27.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 27.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 27.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 26.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 26.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 26.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 26.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 25.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 25.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 25.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 25.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 24.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 24.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 24.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 24.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 24.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 24.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 23.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 22.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 22.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 22.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 21.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 21.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 21.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 21.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 20.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 20.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 20.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 19.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 17.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 14.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

53.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 53.8
FF:10158-103A5 76 years, female 53.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

57.8
Pig sample Sample description nTPM
Substantia nigra
nTPM: 47.0
Samples: 4

Max nTPM: 57.3
Min nTPM: 38.5
Sample A Female 57.3
Sample B Female 38.5
Sample C Male 52.5
Sample D Male 39.5
Midbrain
nTPM: 51.3
Samples: 4

Max nTPM: 66.8
Min nTPM: 40.7
Sample A Female 54.7
Sample B Female 40.7
Sample C Male 66.8
Sample D Male 43.1
Periaqueductal gray
nTPM: 39.0
Samples: 3

Max nTPM: 45.7
Min nTPM: 33.8
Sample B Female 37.4
Sample C Male 45.7
Sample D Male 33.8
Superior colliculi
nTPM: 57.8
Samples: 4

Max nTPM: 81.1
Min nTPM: 40.9
Sample A Female 55.5
Sample B Female 40.9
Sample C Male 81.1
Sample D Male 53.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

62.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 62.6
Samples: 4

Max nTPM: 63.5
Min nTPM: 61.4
Sample A Male 61.4
Sample B Male 62.7
Sample C Female 63.5
Sample D Female 62.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

2.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.8
67978474 Antisense, RP_040923_01_B11, Mouse strain C57BL/6J (56 days, male) 3.0
70919722 Antisense, RP_050713_01_H11, Mouse strain C57BL/6J (56 days, male) 2.6

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