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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:136.2 nTPM
HPA Brain:57.8 nTPM
GTEx:136.2 nTPM
FANTOM5:30.0 Scaled Tags Per Million
Pig:46.7 nTPM
Mouse:86.8 nTPM
Allen mouse:0.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

57.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 46.8
2666 Male, age 74, left hemisphere 52.4
1870 Female, age 42, unknown 51.6
1833 Male, age 53, unknown 51.2
2586 Male, age 75, left hemisphere 50.2
1830 Male, age 51, unknown 50.1
2411 Female, age 72, unknown 45.8
2019 Male, age 18, unknown 43.9
2828 Female, age 72, unknown 43.5
1827 Male, age 72, unknown 41.3
2219 Male, age 76, both hemispheres 38.4
Dorsal raphe nucleus
nTPM: 46.1
2750 Male, age 76, both hemispheres 50.6
2047 Male, age 72, unknown 47.2
2016 Female, age 72, unknown 47.0
1828 Male, age 53, unknown 43.6
2298 Female, age 72, unknown 41.9
Inferior colliculus
nTPM: 40.7
1890 Male, age 53, unknown 43.0
1848 Female, age 42, unknown 42.8
2097 Female, age 72, unknown 39.1
2849 Male, age 72, unknown 37.9
Median raphe nucleus
nTPM: 41.9
2220 Male, age 76, midline 41.9
Periaquaductal grey, anterior
nTPM: 40.7
2502 Female, age 75, unknown 46.9
1947 Male, age 18, unknown 38.5
1795 Male, age 51, unknown 36.7
Periaquaductal grey, dorsal
nTPM: 41.0
2464 Female, age 72, unknown 43.6
1840 Male, age 53, unknown 41.2
2850 Male, age 76, both hemispheres 40.9
1831 Male, age 72, unknown 38.1
Periaquaductal grey, lateral
nTPM: 38.8
2053 Male, age 18, unknown 45.3
2140 Male, age 76, both hemispheres 36.9
2272 Male, age 74, both hemispheres 34.1
Pretectal area
nTPM: 41.4
1817 Female, age 42, unknown 51.5
1815 Male, age 53, unknown 50.8
2316 Male, age 76, right hemisphere 44.7
2224 Female, age 72, unknown 40.7
2825 Male, age 18, unknown 40.0
2007 Male, age 72, unknown 39.8
2667 Female, age 75, unknown 39.1
1816 Male, age 51, unknown 38.9
2407 Male, age 75, both hemispheres 36.8
1944 Female, age 72, unknown 36.5
2273 Male, age 74, both hemispheres 36.2
Red nucleus
nTPM: 57.8
2503 Female, age 72, unknown 69.6
1821 Female, age 72, unknown 68.8
1904 Male, age 53, unknown 62.8
2227 Male, age 72, unknown 62.2
1865 Male, age 51, unknown 62.1
1954 Female, age 42, unknown 61.3
2769 Male, age 72, unknown 56.3
2823 Male, age 76, right hemisphere 55.9
2588 Male, age 74, left hemisphere 54.5
2725 Female, age 75, unknown 50.7
2785 Male, age 18, unknown 48.9
2584 Male, age 75, left hemisphere 40.3
Substantia nigra
nTPM: 43.6
2699 Male, age 18, unknown 51.8
2241 Male, age 72, unknown 50.7
1889 Female, age 72, unknown 46.5
2583 Male, age 75, right hemisphere 45.6
2665 Male, age 74, both hemispheres 44.2
1916 Female, age 42, unknown 42.6
1851 Male, age 51, unknown 42.4
2590 Female, age 75, unknown 40.5
1941 Male, age 53, unknown 36.9
2409 Female, age 72, unknown 34.7
Superior colliculus
nTPM: 44.9
2668 Female, age 75, unknown 49.0
1913 Female, age 42, unknown 48.6
1895 Male, age 76, right hemisphere 48.4
1995 Male, age 72, unknown 46.6
1839 Male, age 51, unknown 45.8
2087 Female, age 72, unknown 44.7
2587 Male, age 74, left hemisphere 43.2
2664 Male, age 75, both hemispheres 42.8
2261 Male, age 18, unknown 42.6
1796 Male, age 53, unknown 37.4
Ventral tegmental area
nTPM: 44.3
2223 Female, age 72, unknown 49.6
2410 Female, age 72, unknown 44.5
1915 Female, age 42, unknown 43.9
1942 Male, age 51, unknown 43.9
2218 Male, age 76, both hemispheres 42.7
2021 Male, age 53, unknown 41.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

136.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 136.2
Samples: 139

Max nTPM: 349.6
Min nTPM: 48.3
Std nTPM: 58.6
Median nTPM: 124.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 349.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 327.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 307.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 298.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 273.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 267.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 258.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 253.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 252.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 238.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 236.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 225.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 221.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 212.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 200.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 199.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 196.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 194.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 192.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 192.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 192.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 188.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 187.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 183.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 182.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 182.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 180.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 179.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 177.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 176.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 173.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 168.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 166.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 165.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 164.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 162.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 161.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 161.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 161.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 161.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 160.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 159.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 158.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 154.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 150.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 149.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 149.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 149.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 148.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 146.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 143.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 143.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 143.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 142.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 141.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 141.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 139.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 139.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 139.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 136.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 136.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 134.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 129.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 129.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 128.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 126.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 125.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 125.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 124.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 124.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 124.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 122.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 118.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 118.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 116.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 116.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 116.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 116.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 115.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 115.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 115.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 115.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 115.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 113.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 112.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 110.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 109.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 109.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 108.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 106.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 106.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 106.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 105.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 101.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 100.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 100.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 99.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 98.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 98.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 97.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 96.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 96.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 96.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 93.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 92.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 92.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 92.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 90.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 90.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 90.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 89.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 88.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 86.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 85.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 85.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 84.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 82.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 81.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 80.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 79.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 78.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 76.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 75.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 75.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 75.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 73.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 73.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 71.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 70.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 67.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 66.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 65.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 64.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 59.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 56.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 51.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 49.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 49.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 48.3
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

30.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 30.0
FF:10158-103A5 76 years, female 30.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

46.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 46.7
Samples: 4

Max nTPM: 63.8
Min nTPM: 37.1
Sample A Female 63.8
Sample B Female 39.2
Sample C Male 46.7
Sample D Male 37.1
Midbrain
nTPM: 46.1
Samples: 4

Max nTPM: 59.9
Min nTPM: 37.5
Sample A Female 59.9
Sample B Female 46.1
Sample C Male 40.9
Sample D Male 37.5
Periaqueductal gray
nTPM: 36.0
Samples: 3

Max nTPM: 39.8
Min nTPM: 31.4
Sample B Female 36.7
Sample C Male 39.8
Sample D Male 31.4
Superior colliculi
nTPM: 40.6
Samples: 4

Max nTPM: 53.6
Min nTPM: 28.6
Sample A Female 53.6
Sample B Female 28.6
Sample C Male 41.8
Sample D Male 38.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

86.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 86.8
Samples: 4

Max nTPM: 91.3
Min nTPM: 82.2
Sample A Male 91.3
Sample B Male 88.7
Sample C Female 84.9
Sample D Female 82.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.0
69015500 Antisense, RP_050315_01_B03, Mouse strain C57BL/6J (56 days, male) 0.0

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