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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:169.2 nTPM
HPA Brain:299.5 nTPM
GTEx:169.2 nTPM
FANTOM5:127.5 Scaled Tags Per Million
Pig:94.4 nTPM
Mouse:195.9 nTPM
Allen mouse:7.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

299.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 216.5
2586 Male, age 75, left hemisphere 318.1
2666 Male, age 74, left hemisphere 270.5
2828 Female, age 72, unknown 225.4
1827 Male, age 72, unknown 211.5
1870 Female, age 42, unknown 207.9
2411 Female, age 72, unknown 194.8
1833 Male, age 53, unknown 192.7
1830 Male, age 51, unknown 191.0
2219 Male, age 76, both hemispheres 178.8
2019 Male, age 18, unknown 174.5
Dorsal raphe nucleus
nTPM: 223.9
2047 Male, age 72, unknown 285.5
2750 Male, age 76, both hemispheres 255.8
2298 Female, age 72, unknown 223.5
1828 Male, age 53, unknown 192.1
2016 Female, age 72, unknown 162.4
Inferior colliculus
nTPM: 144.8
2849 Male, age 72, unknown 163.4
1890 Male, age 53, unknown 145.5
1848 Female, age 42, unknown 143.1
2097 Female, age 72, unknown 127.1
Median raphe nucleus
nTPM: 299.5
2220 Male, age 76, midline 299.5
Periaquaductal grey, anterior
nTPM: 229.0
1795 Male, age 51, unknown 257.5
1947 Male, age 18, unknown 228.8
2502 Female, age 75, unknown 200.5
Periaquaductal grey, dorsal
nTPM: 175.1
2850 Male, age 76, both hemispheres 200.1
1831 Male, age 72, unknown 170.0
1840 Male, age 53, unknown 167.4
2464 Female, age 72, unknown 162.8
Periaquaductal grey, lateral
nTPM: 166.6
2053 Male, age 18, unknown 166.8
2140 Male, age 76, both hemispheres 166.6
2272 Male, age 74, both hemispheres 166.6
Pretectal area
nTPM: 190.7
2007 Male, age 72, unknown 214.8
1815 Male, age 53, unknown 210.1
1816 Male, age 51, unknown 209.1
1817 Female, age 42, unknown 204.6
2825 Male, age 18, unknown 204.1
2407 Male, age 75, both hemispheres 201.4
1944 Female, age 72, unknown 196.7
2224 Female, age 72, unknown 188.7
2667 Female, age 75, unknown 184.5
2316 Male, age 76, right hemisphere 150.3
2273 Male, age 74, both hemispheres 133.3
Red nucleus
nTPM: 193.4
2584 Male, age 75, left hemisphere 294.1
2725 Female, age 75, unknown 214.4
2588 Male, age 74, left hemisphere 197.2
2785 Male, age 18, unknown 192.5
1865 Male, age 51, unknown 186.6
2769 Male, age 72, unknown 185.0
1904 Male, age 53, unknown 182.4
2823 Male, age 76, right hemisphere 181.3
1821 Female, age 72, unknown 175.7
2227 Male, age 72, unknown 173.4
2503 Female, age 72, unknown 170.1
1954 Female, age 42, unknown 167.9
Substantia nigra
nTPM: 256.6
1916 Female, age 42, unknown 367.3
2665 Male, age 74, both hemispheres 308.8
1851 Male, age 51, unknown 282.1
2583 Male, age 75, right hemisphere 267.5
1941 Male, age 53, unknown 264.6
2699 Male, age 18, unknown 260.1
2590 Female, age 75, unknown 221.0
1889 Female, age 72, unknown 204.0
2409 Female, age 72, unknown 200.1
2241 Male, age 72, unknown 190.4
Superior colliculus
nTPM: 191.4
2664 Male, age 75, both hemispheres 228.3
2668 Female, age 75, unknown 223.6
1796 Male, age 53, unknown 215.6
2261 Male, age 18, unknown 204.3
1913 Female, age 42, unknown 189.5
2587 Male, age 74, left hemisphere 187.4
2087 Female, age 72, unknown 180.4
1995 Male, age 72, unknown 175.7
1839 Male, age 51, unknown 170.7
1895 Male, age 76, right hemisphere 138.1
Ventral tegmental area
nTPM: 238.6
1915 Female, age 42, unknown 258.2
2223 Female, age 72, unknown 256.7
2021 Male, age 53, unknown 244.2
2218 Male, age 76, both hemispheres 236.3
2410 Female, age 72, unknown 221.3
1942 Male, age 51, unknown 214.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

169.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 169.2
Samples: 139

Max nTPM: 291.3
Min nTPM: 82.1
Std nTPM: 33.6
Median nTPM: 165.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 291.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 251.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 238.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 234.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 231.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 229.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 227.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 227.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 226.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 226.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 224.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 221.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 215.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 214.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 214.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 213.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 208.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 208.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 207.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 206.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 205.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 205.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 202.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 199.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 198.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 195.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 195.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 195.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 194.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 194.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 191.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 190.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 190.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 190.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 190.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 189.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 188.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 188.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 187.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 187.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 187.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 186.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 185.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 184.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 183.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 182.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 182.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 180.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 180.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 179.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 179.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 179.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 176.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 176.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 175.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 175.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 175.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 175.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 174.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 170.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 170.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 169.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 169.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 168.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 168.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 167.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 167.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 166.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 166.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 165.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 165.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 163.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 162.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 162.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 161.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 161.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 161.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 161.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 160.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 159.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 158.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 158.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 157.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 157.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 155.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 154.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 154.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 153.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 153.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 153.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 153.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 152.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 152.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 152.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 151.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 151.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 150.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 150.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 149.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 149.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 149.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 148.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 148.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 148.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 148.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 147.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 147.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 146.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 146.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 145.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 145.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 144.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 143.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 142.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 142.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 140.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 140.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 139.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 139.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 139.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 137.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 137.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 136.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 135.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 133.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 131.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 130.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 125.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 124.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 121.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 120.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 119.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 112.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 111.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 104.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 103.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 96.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 94.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 82.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

127.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 127.5
FF:10158-103A5 76 years, female 127.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

94.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 94.4
Samples: 4

Max nTPM: 108.7
Min nTPM: 81.0
Sample A Female 108.7
Sample B Female 81.0
Sample C Male 102.3
Sample D Male 85.6
Midbrain
nTPM: 86.4
Samples: 4

Max nTPM: 138.2
Min nTPM: 58.4
Sample A Female 138.2
Sample B Female 81.8
Sample C Male 67.1
Sample D Male 58.4
Periaqueductal gray
nTPM: 72.0
Samples: 3

Max nTPM: 82.0
Min nTPM: 64.7
Sample B Female 69.4
Sample C Male 82.0
Sample D Male 64.7
Superior colliculi
nTPM: 77.4
Samples: 4

Max nTPM: 90.0
Min nTPM: 68.8
Sample A Female 90.0
Sample B Female 73.5
Sample C Male 68.8
Sample D Male 77.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

195.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 195.9
Samples: 4

Max nTPM: 206.7
Min nTPM: 186.1
Sample A Male 202.3
Sample B Male 188.5
Sample C Female 186.1
Sample D Female 206.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

7.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 7.3
75774677 Antisense, RP_060530_01_D02, Mouse strain C57BL/6J (56 days, male) 12.2
633678 Antisense, RP_040907_02_A10, Mouse strain C57BL/6J (56 days, male) 2.3

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