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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:1458.1 nTPM
HPA Brain:462.2 nTPM
GTEx:1458.1 nTPM
FANTOM5:29.8 Scaled Tags Per Million
Pig:201.1 nTPM
Mouse:734.3 nTPM
Allen mouse:4.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

462.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 403.9
2666 Male, age 74, left hemisphere 452.5
2411 Female, age 72, unknown 446.2
1870 Female, age 42, unknown 419.9
1833 Male, age 53, unknown 413.3
2828 Female, age 72, unknown 408.8
2219 Male, age 76, both hemispheres 398.6
1830 Male, age 51, unknown 393.0
1827 Male, age 72, unknown 389.5
2586 Male, age 75, left hemisphere 381.8
2019 Male, age 18, unknown 335.0
Dorsal raphe nucleus
nTPM: 390.4
2750 Male, age 76, both hemispheres 444.5
2298 Female, age 72, unknown 417.4
2016 Female, age 72, unknown 377.7
1828 Male, age 53, unknown 372.4
2047 Male, age 72, unknown 340.0
Inferior colliculus
nTPM: 382.9
2849 Male, age 72, unknown 416.3
1890 Male, age 53, unknown 405.4
1848 Female, age 42, unknown 365.4
2097 Female, age 72, unknown 344.3
Median raphe nucleus
nTPM: 392.0
2220 Male, age 76, midline 392.0
Periaquaductal grey, anterior
nTPM: 384.6
2502 Female, age 75, unknown 429.6
1795 Male, age 51, unknown 371.1
1947 Male, age 18, unknown 353.1
Periaquaductal grey, dorsal
nTPM: 394.4
2850 Male, age 76, both hemispheres 418.4
1840 Male, age 53, unknown 407.8
2464 Female, age 72, unknown 385.4
1831 Male, age 72, unknown 365.8
Periaquaductal grey, lateral
nTPM: 375.6
2053 Male, age 18, unknown 420.2
2140 Male, age 76, both hemispheres 364.9
2272 Male, age 74, both hemispheres 341.6
Pretectal area
nTPM: 371.1
1817 Female, age 42, unknown 436.8
1815 Male, age 53, unknown 415.3
2316 Male, age 76, right hemisphere 415.2
2007 Male, age 72, unknown 399.5
2224 Female, age 72, unknown 385.6
2825 Male, age 18, unknown 380.5
1944 Female, age 72, unknown 371.4
1816 Male, age 51, unknown 354.1
2407 Male, age 75, both hemispheres 311.4
2667 Female, age 75, unknown 309.2
2273 Male, age 74, both hemispheres 302.5
Red nucleus
nTPM: 422.9
2503 Female, age 72, unknown 500.8
1821 Female, age 72, unknown 463.9
1865 Male, age 51, unknown 456.4
2725 Female, age 75, unknown 443.3
2588 Male, age 74, left hemisphere 427.2
1904 Male, age 53, unknown 425.9
2769 Male, age 72, unknown 416.4
2584 Male, age 75, left hemisphere 415.1
2227 Male, age 72, unknown 407.7
2785 Male, age 18, unknown 382.4
2823 Male, age 76, right hemisphere 382.3
1954 Female, age 42, unknown 353.5
Substantia nigra
nTPM: 462.2
2699 Male, age 18, unknown 637.4
2409 Female, age 72, unknown 576.2
1851 Male, age 51, unknown 564.1
2665 Male, age 74, both hemispheres 499.3
1916 Female, age 42, unknown 451.6
2241 Male, age 72, unknown 428.0
1889 Female, age 72, unknown 399.0
2590 Female, age 75, unknown 396.1
1941 Male, age 53, unknown 358.7
2583 Male, age 75, right hemisphere 312.0
Superior colliculus
nTPM: 411.9
1913 Female, age 42, unknown 487.4
2587 Male, age 74, left hemisphere 486.0
1995 Male, age 72, unknown 483.3
2668 Female, age 75, unknown 469.1
1796 Male, age 53, unknown 410.7
1839 Male, age 51, unknown 383.1
1895 Male, age 76, right hemisphere 366.9
2261 Male, age 18, unknown 357.4
2087 Female, age 72, unknown 344.7
2664 Male, age 75, both hemispheres 330.7
Ventral tegmental area
nTPM: 453.4
2410 Female, age 72, unknown 515.2
2223 Female, age 72, unknown 496.1
1915 Female, age 42, unknown 467.4
2021 Male, age 53, unknown 456.7
2218 Male, age 76, both hemispheres 395.1
1942 Male, age 51, unknown 389.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1458.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 1458.1
Samples: 139

Max nTPM: 5375.5
Min nTPM: 478.7
Std nTPM: 624.4
Median nTPM: 1341.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 5375.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 3684.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 3355.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 3253.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 2905.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 2600.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 2437.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 2341.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 2335.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 2217.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 2197.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 2165.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 2155.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 2152.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 2056.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 2048.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 2033.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 2020.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 2019.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1978.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1939.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 1922.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1918.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 1903.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1852.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1808.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 1787.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1785.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 1758.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1746.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 1742.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1737.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1708.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 1692.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1686.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 1684.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1668.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1638.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 1637.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 1610.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 1609.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1606.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1588.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1573.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 1567.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 1560.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 1550.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1550.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 1547.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 1545.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 1544.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 1542.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 1519.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1491.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 1477.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 1471.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 1468.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1468.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 1456.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 1451.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 1435.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1435.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1427.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 1417.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 1404.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1403.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1402.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 1385.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 1369.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 1341.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 1330.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 1326.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 1318.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 1314.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1312.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 1282.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 1267.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 1244.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 1243.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1236.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 1217.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 1208.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 1205.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 1201.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 1188.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 1178.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 1169.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 1168.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 1160.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 1160.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 1143.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 1128.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1122.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 1122.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 1119.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 1119.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 1116.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 1103.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 1102.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 1102.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 1098.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 1082.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 1071.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 1047.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 1044.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 1037.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 1034.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 1030.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 1029.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 1021.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 1002.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 986.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 974.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 970.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 964.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 949.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 945.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 934.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 918.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 911.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 909.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 906.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 898.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 895.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 887.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 884.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 874.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 870.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 864.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 861.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 860.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 860.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 812.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 795.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 749.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 745.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 692.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 689.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 478.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

29.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 29.8
FF:10158-103A5 76 years, female 29.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

201.1
Pig sample Sample description nTPM
Substantia nigra
nTPM: 198.0
Samples: 4

Max nTPM: 256.6
Min nTPM: 156.5
Sample A Female 256.6
Sample B Female 199.9
Sample C Male 178.8
Sample D Male 156.5
Midbrain
nTPM: 192.0
Samples: 4

Max nTPM: 243.5
Min nTPM: 139.0
Sample A Female 243.5
Sample B Female 206.8
Sample C Male 178.8
Sample D Male 139.0
Periaqueductal gray
nTPM: 155.3
Samples: 3

Max nTPM: 168.8
Min nTPM: 135.3
Sample B Female 168.8
Sample C Male 161.8
Sample D Male 135.3
Superior colliculi
nTPM: 201.2
Samples: 4

Max nTPM: 239.5
Min nTPM: 159.6
Sample A Female 239.5
Sample B Female 210.8
Sample C Male 194.7
Sample D Male 159.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

734.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 734.3
Samples: 4

Max nTPM: 819.7
Min nTPM: 661.7
Sample A Male 819.7
Sample B Male 712.1
Sample C Female 661.7
Sample D Female 743.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

4.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.3
75934920 Antisense, RP_060530_01_E12, Mouse strain C57BL/6J (56 days, male) 7.1
69012729 Antisense, RP_050309_01_D03, Mouse strain C57BL/6J (56 days, male) 1.6

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