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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:66.3 nTPM
HPA Brain:61.2 nTPM
GTEx:66.3 nTPM
FANTOM5:16.8 Scaled Tags Per Million
Pig:88.0 nTPM
Mouse:54.9 nTPM
Allen mouse:0.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

61.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 19.9
1827 Male, age 72, unknown 24.6
2019 Male, age 18, unknown 24.6
2411 Female, age 72, unknown 20.4
2828 Female, age 72, unknown 20.1
1870 Female, age 42, unknown 20.0
1833 Male, age 53, unknown 19.5
2586 Male, age 75, left hemisphere 18.0
1830 Male, age 51, unknown 17.9
2666 Male, age 74, left hemisphere 17.3
2219 Male, age 76, both hemispheres 16.7
Dorsal raphe nucleus
nTPM: 39.9
2298 Female, age 72, unknown 67.1
2016 Female, age 72, unknown 51.0
1828 Male, age 53, unknown 33.0
2047 Male, age 72, unknown 28.5
2750 Male, age 76, both hemispheres 20.1
Inferior colliculus
nTPM: 23.1
2097 Female, age 72, unknown 27.2
2849 Male, age 72, unknown 23.4
1890 Male, age 53, unknown 21.4
1848 Female, age 42, unknown 20.5
Median raphe nucleus
nTPM: 29.6
2220 Male, age 76, midline 29.6
Periaquaductal grey, anterior
nTPM: 32.3
1795 Male, age 51, unknown 38.5
1947 Male, age 18, unknown 30.8
2502 Female, age 75, unknown 27.7
Periaquaductal grey, dorsal
nTPM: 43.3
2850 Male, age 76, both hemispheres 70.1
1840 Male, age 53, unknown 42.5
1831 Male, age 72, unknown 31.7
2464 Female, age 72, unknown 28.9
Periaquaductal grey, lateral
nTPM: 61.2
2272 Male, age 74, both hemispheres 101.2
2140 Male, age 76, both hemispheres 54.6
2053 Male, age 18, unknown 27.7
Pretectal area
nTPM: 34.5
2273 Male, age 74, both hemispheres 89.3
2224 Female, age 72, unknown 46.0
1816 Male, age 51, unknown 30.7
2667 Female, age 75, unknown 30.5
1817 Female, age 42, unknown 30.1
1815 Male, age 53, unknown 29.9
2825 Male, age 18, unknown 28.9
1944 Female, age 72, unknown 27.9
2007 Male, age 72, unknown 26.3
2407 Male, age 75, both hemispheres 21.2
2316 Male, age 76, right hemisphere 19.2
Red nucleus
nTPM: 19.2
2725 Female, age 75, unknown 26.1
2785 Male, age 18, unknown 25.3
2769 Male, age 72, unknown 20.2
2227 Male, age 72, unknown 19.8
2503 Female, age 72, unknown 19.4
1821 Female, age 72, unknown 19.1
1954 Female, age 42, unknown 19.1
1865 Male, age 51, unknown 19.0
1904 Male, age 53, unknown 17.6
2823 Male, age 76, right hemisphere 15.4
2588 Male, age 74, left hemisphere 14.9
2584 Male, age 75, left hemisphere 14.8
Substantia nigra
nTPM: 24.2
1941 Male, age 53, unknown 27.9
1916 Female, age 42, unknown 27.5
2699 Male, age 18, unknown 27.0
2590 Female, age 75, unknown 26.4
1889 Female, age 72, unknown 26.0
1851 Male, age 51, unknown 25.0
2241 Male, age 72, unknown 24.2
2409 Female, age 72, unknown 21.5
2665 Male, age 74, both hemispheres 18.8
2583 Male, age 75, right hemisphere 17.7
Superior colliculus
nTPM: 26.3
2587 Male, age 74, left hemisphere 38.3
1995 Male, age 72, unknown 35.4
2261 Male, age 18, unknown 30.5
2087 Female, age 72, unknown 26.0
2664 Male, age 75, both hemispheres 25.2
1796 Male, age 53, unknown 24.4
1839 Male, age 51, unknown 22.5
1913 Female, age 42, unknown 22.5
2668 Female, age 75, unknown 20.2
1895 Male, age 76, right hemisphere 17.8
Ventral tegmental area
nTPM: 24.8
2021 Male, age 53, unknown 29.3
1915 Female, age 42, unknown 27.1
1942 Male, age 51, unknown 25.2
2218 Male, age 76, both hemispheres 23.6
2223 Female, age 72, unknown 22.8
2410 Female, age 72, unknown 21.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

66.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 66.3
Samples: 139

Max nTPM: 183.0
Min nTPM: 18.1
Std nTPM: 21.5
Median nTPM: 61.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 183.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 130.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 126.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 119.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 119.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 109.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 104.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 103.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 96.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 94.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 91.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 91.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 90.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 89.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 89.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 89.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 89.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 88.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 87.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 87.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 85.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 85.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 85.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 85.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 85.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 84.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 83.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 81.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 81.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 81.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 79.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 78.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 78.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 77.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 77.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 76.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 75.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 75.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 74.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 74.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 74.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 74.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 72.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 72.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 71.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 70.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 70.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 70.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 69.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 69.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 69.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 68.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 66.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 66.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 66.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 66.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 65.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 65.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 64.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 64.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 64.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 63.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 63.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 63.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 63.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 62.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 62.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 61.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 61.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 61.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 61.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 61.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 61.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 60.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 60.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 59.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 59.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 59.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 59.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 59.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 59.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 58.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 58.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 58.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 57.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 57.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 57.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 57.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 57.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 57.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 57.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 56.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 56.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 56.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 56.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 56.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 56.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 55.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 55.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 55.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 54.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 54.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 54.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 54.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 54.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 53.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 53.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 52.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 50.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 50.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 50.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 50.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 49.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 49.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 49.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 48.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 48.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 48.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 48.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 47.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 46.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 46.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 46.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 45.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 44.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 44.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 42.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 42.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 42.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 41.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 40.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 39.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 38.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 38.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 37.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 36.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 33.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 30.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 18.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

16.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 16.8
FF:10158-103A5 76 years, female 16.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

88.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 46.2
Samples: 4

Max nTPM: 57.0
Min nTPM: 41.1
Sample A Female 57.0
Sample B Female 42.1
Sample C Male 44.7
Sample D Male 41.1
Midbrain
nTPM: 56.9
Samples: 4

Max nTPM: 79.2
Min nTPM: 43.0
Sample A Female 79.2
Sample B Female 58.9
Sample C Male 43.0
Sample D Male 46.3
Periaqueductal gray
nTPM: 88.0
Samples: 3

Max nTPM: 102.5
Min nTPM: 70.5
Sample B Female 70.5
Sample C Male 91.0
Sample D Male 102.5
Superior colliculi
nTPM: 55.2
Samples: 4

Max nTPM: 61.7
Min nTPM: 49.8
Sample A Female 61.7
Sample B Female 59.5
Sample C Male 49.8
Sample D Male 49.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

54.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 54.9
Samples: 4

Max nTPM: 56.5
Min nTPM: 51.3
Sample A Male 55.6
Sample B Male 56.5
Sample C Female 51.3
Sample D Female 56.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.4
69838701 Antisense, RP_050317_04_F04, Mouse strain C57BL/6J (56 days, male) 0.8
77910681 Antisense, RP_070208_04_E11, Mouse strain C57BL/6J (56 days, male) 0.0

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