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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:137.1 nTPM
HPA Brain:129.6 nTPM
GTEx:137.1 nTPM
FANTOM5:113.2 Scaled Tags Per Million
Pig:107.7 nTPM
Mouse:114.2 nTPM
Allen mouse:3.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

129.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 114.9
2586 Male, age 75, left hemisphere 159.1
2828 Female, age 72, unknown 125.7
2666 Male, age 74, left hemisphere 118.4
1833 Male, age 53, unknown 112.2
2019 Male, age 18, unknown 110.8
2411 Female, age 72, unknown 110.8
1830 Male, age 51, unknown 107.3
1827 Male, age 72, unknown 106.4
1870 Female, age 42, unknown 105.9
2219 Male, age 76, both hemispheres 92.8
Dorsal raphe nucleus
nTPM: 111.3
1828 Male, age 53, unknown 120.0
2047 Male, age 72, unknown 118.5
2750 Male, age 76, both hemispheres 111.0
2016 Female, age 72, unknown 103.9
2298 Female, age 72, unknown 103.0
Inferior colliculus
nTPM: 101.9
2849 Male, age 72, unknown 105.6
1890 Male, age 53, unknown 102.0
1848 Female, age 42, unknown 101.7
2097 Female, age 72, unknown 98.1
Median raphe nucleus
nTPM: 108.0
2220 Male, age 76, midline 108.0
Periaquaductal grey, anterior
nTPM: 106.6
2502 Female, age 75, unknown 111.7
1795 Male, age 51, unknown 106.0
1947 Male, age 18, unknown 102.0
Periaquaductal grey, dorsal
nTPM: 98.3
1840 Male, age 53, unknown 102.7
1831 Male, age 72, unknown 97.4
2850 Male, age 76, both hemispheres 96.5
2464 Female, age 72, unknown 96.4
Periaquaductal grey, lateral
nTPM: 92.8
2053 Male, age 18, unknown 99.4
2140 Male, age 76, both hemispheres 93.4
2272 Male, age 74, both hemispheres 85.7
Pretectal area
nTPM: 105.5
1817 Female, age 42, unknown 125.4
1815 Male, age 53, unknown 117.1
2007 Male, age 72, unknown 115.5
1816 Male, age 51, unknown 109.6
2407 Male, age 75, both hemispheres 108.8
2667 Female, age 75, unknown 105.1
1944 Female, age 72, unknown 103.9
2825 Male, age 18, unknown 103.4
2316 Male, age 76, right hemisphere 93.4
2273 Male, age 74, both hemispheres 90.7
2224 Female, age 72, unknown 86.9
Red nucleus
nTPM: 117.9
2588 Male, age 74, left hemisphere 124.6
2584 Male, age 75, left hemisphere 124.5
1821 Female, age 72, unknown 123.8
2769 Male, age 72, unknown 123.0
2503 Female, age 72, unknown 118.4
2227 Male, age 72, unknown 118.2
1865 Male, age 51, unknown 116.0
2785 Male, age 18, unknown 115.9
1954 Female, age 42, unknown 114.7
1904 Male, age 53, unknown 114.3
2823 Male, age 76, right hemisphere 114.3
2725 Female, age 75, unknown 106.7
Substantia nigra
nTPM: 129.6
1916 Female, age 42, unknown 167.9
1851 Male, age 51, unknown 146.6
2665 Male, age 74, both hemispheres 140.9
2699 Male, age 18, unknown 137.2
2583 Male, age 75, right hemisphere 131.9
2409 Female, age 72, unknown 119.8
2590 Female, age 75, unknown 114.9
2241 Male, age 72, unknown 114.4
1889 Female, age 72, unknown 112.4
1941 Male, age 53, unknown 110.2
Superior colliculus
nTPM: 110.2
2664 Male, age 75, both hemispheres 135.6
2668 Female, age 75, unknown 128.7
2587 Male, age 74, left hemisphere 109.6
1796 Male, age 53, unknown 108.1
1839 Male, age 51, unknown 107.9
2261 Male, age 18, unknown 105.9
1995 Male, age 72, unknown 104.0
2087 Female, age 72, unknown 102.6
1913 Female, age 42, unknown 101.5
1895 Male, age 76, right hemisphere 98.6
Ventral tegmental area
nTPM: 119.9
1915 Female, age 42, unknown 128.9
2410 Female, age 72, unknown 128.0
2218 Male, age 76, both hemispheres 124.2
2021 Male, age 53, unknown 116.9
2223 Female, age 72, unknown 110.8
1942 Male, age 51, unknown 110.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

137.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 137.1
Samples: 139

Max nTPM: 258.7
Min nTPM: 79.0
Std nTPM: 30.0
Median nTPM: 132.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 258.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 239.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 230.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 220.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 197.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 193.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 182.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 181.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 180.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 179.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 178.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 175.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 174.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 174.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 173.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 172.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 172.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 167.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 166.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 165.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 164.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 164.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 164.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 163.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 162.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 159.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 159.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 159.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 158.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 158.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 157.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 155.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 154.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 154.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 154.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 153.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 153.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 152.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 151.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 151.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 149.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 149.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 149.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 148.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 148.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 148.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 147.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 147.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 146.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 145.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 144.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 144.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 142.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 142.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 141.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 141.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 140.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 139.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 138.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 138.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 137.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 137.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 136.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 136.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 135.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 135.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 135.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 135.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 134.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 132.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 132.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 131.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 130.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 130.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 129.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 129.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 128.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 128.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 127.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 127.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 127.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 126.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 126.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 125.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 124.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 124.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 123.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 123.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 123.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 122.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 121.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 120.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 120.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 120.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 119.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 119.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 119.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 119.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 118.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 118.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 118.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 118.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 118.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 117.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 117.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 116.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 116.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 116.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 116.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 115.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 113.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 113.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 112.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 111.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 110.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 109.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 109.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 109.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 109.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 109.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 108.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 108.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 105.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 103.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 103.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 102.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 101.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 100.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 99.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 99.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 97.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 96.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 96.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 95.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 93.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 90.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 82.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 81.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 79.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

113.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 113.2
FF:10158-103A5 76 years, female 113.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

107.7
Pig sample Sample description nTPM
Substantia nigra
nTPM: 96.6
Samples: 4

Max nTPM: 119.1
Min nTPM: 79.9
Sample A Female 119.1
Sample B Female 79.9
Sample C Male 100.8
Sample D Male 86.6
Midbrain
nTPM: 103.1
Samples: 4

Max nTPM: 111.8
Min nTPM: 94.4
Sample A Female 111.8
Sample B Female 94.4
Sample C Male 110.5
Sample D Male 95.8
Periaqueductal gray
nTPM: 84.2
Samples: 3

Max nTPM: 93.8
Min nTPM: 74.3
Sample B Female 84.4
Sample C Male 93.8
Sample D Male 74.3
Superior colliculi
nTPM: 107.7
Samples: 4

Max nTPM: 125.8
Min nTPM: 84.7
Sample A Female 125.8
Sample B Female 84.7
Sample C Male 113.3
Sample D Male 106.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

114.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 114.2
Samples: 4

Max nTPM: 121.6
Min nTPM: 108.0
Sample A Male 121.6
Sample B Male 109.4
Sample C Female 108.0
Sample D Female 117.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

3.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.7
72283773 Antisense, RP_051019_02_B04, Mouse strain C57BL/6J (56 days, male) 6.8
74736207 Antisense, RP_060302_02_E06, Mouse strain C57BL/6J (56 days, male) 0.5

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