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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:532.5 nTPM
HPA Brain:206.4 nTPM
GTEx:532.5 nTPM
FANTOM5:691.2 Scaled Tags Per Million
Pig:269.6 nTPM
Mouse:477.0 nTPM
Allen mouse:17.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

206.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 168.8
2586 Male, age 75, left hemisphere 209.3
2411 Female, age 72, unknown 200.5
1870 Female, age 42, unknown 195.6
2019 Male, age 18, unknown 193.5
1830 Male, age 51, unknown 186.5
1833 Male, age 53, unknown 180.2
2666 Male, age 74, left hemisphere 139.2
1827 Male, age 72, unknown 135.6
2828 Female, age 72, unknown 132.8
2219 Male, age 76, both hemispheres 115.3
Dorsal raphe nucleus
nTPM: 141.4
2750 Male, age 76, both hemispheres 185.6
2047 Male, age 72, unknown 144.6
1828 Male, age 53, unknown 137.0
2016 Female, age 72, unknown 124.2
2298 Female, age 72, unknown 115.8
Inferior colliculus
nTPM: 138.7
1890 Male, age 53, unknown 156.4
1848 Female, age 42, unknown 140.2
2097 Female, age 72, unknown 137.9
2849 Male, age 72, unknown 120.2
Median raphe nucleus
nTPM: 151.7
2220 Male, age 76, midline 151.7
Periaquaductal grey, anterior
nTPM: 116.6
1947 Male, age 18, unknown 131.0
2502 Female, age 75, unknown 120.0
1795 Male, age 51, unknown 99.0
Periaquaductal grey, dorsal
nTPM: 106.0
2464 Female, age 72, unknown 123.8
1831 Male, age 72, unknown 108.7
1840 Male, age 53, unknown 99.2
2850 Male, age 76, both hemispheres 92.4
Periaquaductal grey, lateral
nTPM: 104.0
2053 Male, age 18, unknown 127.6
2272 Male, age 74, both hemispheres 96.7
2140 Male, age 76, both hemispheres 87.7
Pretectal area
nTPM: 120.1
1815 Male, age 53, unknown 147.1
1817 Female, age 42, unknown 140.4
2007 Male, age 72, unknown 136.3
2407 Male, age 75, both hemispheres 131.3
2316 Male, age 76, right hemisphere 120.0
2825 Male, age 18, unknown 118.9
2667 Female, age 75, unknown 112.4
1944 Female, age 72, unknown 108.5
2224 Female, age 72, unknown 107.1
1816 Male, age 51, unknown 105.5
2273 Male, age 74, both hemispheres 94.2
Red nucleus
nTPM: 206.4
1821 Female, age 72, unknown 249.5
2588 Male, age 74, left hemisphere 235.8
1904 Male, age 53, unknown 227.1
1865 Male, age 51, unknown 222.8
2227 Male, age 72, unknown 213.3
1954 Female, age 42, unknown 211.1
2769 Male, age 72, unknown 207.5
2503 Female, age 72, unknown 189.0
2823 Male, age 76, right hemisphere 186.9
2785 Male, age 18, unknown 181.0
2584 Male, age 75, left hemisphere 177.8
2725 Female, age 75, unknown 175.5
Substantia nigra
nTPM: 145.3
2583 Male, age 75, right hemisphere 175.8
1851 Male, age 51, unknown 161.9
1889 Female, age 72, unknown 153.9
2241 Male, age 72, unknown 152.3
2409 Female, age 72, unknown 151.8
2590 Female, age 75, unknown 138.1
1916 Female, age 42, unknown 133.1
1941 Male, age 53, unknown 132.4
2665 Male, age 74, both hemispheres 128.3
2699 Male, age 18, unknown 125.3
Superior colliculus
nTPM: 138.2
2668 Female, age 75, unknown 171.0
2587 Male, age 74, left hemisphere 160.0
1913 Female, age 42, unknown 151.9
1839 Male, age 51, unknown 144.4
2664 Male, age 75, both hemispheres 141.7
1995 Male, age 72, unknown 141.5
1895 Male, age 76, right hemisphere 140.2
1796 Male, age 53, unknown 116.1
2261 Male, age 18, unknown 109.1
2087 Female, age 72, unknown 106.3
Ventral tegmental area
nTPM: 157.9
2223 Female, age 72, unknown 229.6
2410 Female, age 72, unknown 165.3
2218 Male, age 76, both hemispheres 146.0
1942 Male, age 51, unknown 141.2
1915 Female, age 42, unknown 138.0
2021 Male, age 53, unknown 127.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

532.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 532.5
Samples: 139

Max nTPM: 1115.0
Min nTPM: 211.6
Std nTPM: 168.3
Median nTPM: 499.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1115.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1086.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1004.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 919.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 913.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 892.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 864.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 860.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 856.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 851.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 811.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 782.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 780.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 776.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 774.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 741.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 727.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 720.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 707.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 693.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 686.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 683.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 683.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 672.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 666.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 663.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 658.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 655.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 654.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 645.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 645.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 645.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 642.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 635.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 627.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 618.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 602.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 599.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 591.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 590.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 589.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 582.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 580.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 580.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 575.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 572.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 572.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 571.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 568.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 568.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 567.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 566.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 564.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 562.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 561.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 560.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 557.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 553.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 549.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 536.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 535.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 534.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 531.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 524.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 520.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 515.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 514.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 512.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 501.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 499.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 497.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 494.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 491.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 489.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 487.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 478.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 478.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 476.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 468.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 468.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 466.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 462.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 461.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 461.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 458.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 457.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 452.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 448.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 448.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 445.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 444.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 440.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 440.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 439.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 433.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 428.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 426.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 420.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 420.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 418.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 418.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 418.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 418.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 412.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 412.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 409.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 408.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 408.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 404.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 403.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 402.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 383.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 382.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 380.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 378.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 378.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 374.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 371.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 369.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 366.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 366.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 366.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 364.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 359.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 357.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 355.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 339.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 337.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 336.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 329.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 320.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 316.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 310.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 305.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 300.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 293.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 291.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 269.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 211.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

691.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 691.2
FF:10158-103A5 76 years, female 691.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

269.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 204.4
Samples: 4

Max nTPM: 293.2
Min nTPM: 129.9
Sample A Female 222.0
Sample B Female 129.9
Sample C Male 172.4
Sample D Male 293.2
Midbrain
nTPM: 269.6
Samples: 4

Max nTPM: 583.8
Min nTPM: 147.1
Sample A Female 583.8
Sample B Female 198.2
Sample C Male 147.1
Sample D Male 149.3
Periaqueductal gray
nTPM: 153.5
Samples: 3

Max nTPM: 172.3
Min nTPM: 139.6
Sample B Female 172.3
Sample C Male 139.6
Sample D Male 148.6
Superior colliculi
nTPM: 191.5
Samples: 4

Max nTPM: 227.3
Min nTPM: 114.1
Sample A Female 223.8
Sample B Female 114.1
Sample C Male 200.6
Sample D Male 227.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

477.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 477.0
Samples: 4

Max nTPM: 495.2
Min nTPM: 469.2
Sample A Male 470.1
Sample B Male 469.2
Sample C Female 473.6
Sample D Female 495.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

17.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 17.7
68632051 Antisense, RP_050125_01_F03, Mouse strain C57BL/6J (56 days, male) 17.7

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