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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:707.1 nTPM
HPA Brain:968.7 nTPM
GTEx:707.1 nTPM
FANTOM5:1132.2 Scaled Tags Per Million
Pig:303.2 nTPM
Mouse:480.9 nTPM
Allen mouse:13.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

968.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 638.4
2019 Male, age 18, unknown 766.6
2411 Female, age 72, unknown 761.3
2666 Male, age 74, left hemisphere 726.6
1833 Male, age 53, unknown 720.5
1830 Male, age 51, unknown 689.9
1870 Female, age 42, unknown 674.3
2828 Female, age 72, unknown 626.9
2219 Male, age 76, both hemispheres 503.4
1827 Male, age 72, unknown 468.4
2586 Male, age 75, left hemisphere 446.1
Dorsal raphe nucleus
nTPM: 475.8
2750 Male, age 76, both hemispheres 711.8
1828 Male, age 53, unknown 487.4
2016 Female, age 72, unknown 466.3
2047 Male, age 72, unknown 378.5
2298 Female, age 72, unknown 334.7
Inferior colliculus
nTPM: 448.6
1890 Male, age 53, unknown 492.8
2097 Female, age 72, unknown 460.9
1848 Female, age 42, unknown 446.8
2849 Male, age 72, unknown 393.8
Median raphe nucleus
nTPM: 384.4
2220 Male, age 76, midline 384.4
Periaquaductal grey, anterior
nTPM: 420.6
2502 Female, age 75, unknown 485.4
1947 Male, age 18, unknown 462.5
1795 Male, age 51, unknown 314.0
Periaquaductal grey, dorsal
nTPM: 288.5
2464 Female, age 72, unknown 467.6
1831 Male, age 72, unknown 265.0
1840 Male, age 53, unknown 213.5
2850 Male, age 76, both hemispheres 207.9
Periaquaductal grey, lateral
nTPM: 280.1
2272 Male, age 74, both hemispheres 319.9
2053 Male, age 18, unknown 318.2
2140 Male, age 76, both hemispheres 202.3
Pretectal area
nTPM: 396.7
1815 Male, age 53, unknown 594.2
2316 Male, age 76, right hemisphere 566.3
1817 Female, age 42, unknown 560.3
2007 Male, age 72, unknown 520.7
2825 Male, age 18, unknown 381.4
2407 Male, age 75, both hemispheres 323.3
2224 Female, age 72, unknown 306.4
1816 Male, age 51, unknown 305.1
2273 Male, age 74, both hemispheres 274.0
1944 Female, age 72, unknown 271.5
2667 Female, age 75, unknown 260.6
Red nucleus
nTPM: 968.7
1821 Female, age 72, unknown 1250.6
1904 Male, age 53, unknown 1175.6
2503 Female, age 72, unknown 1164.4
1865 Male, age 51, unknown 1053.0
1954 Female, age 42, unknown 1045.8
2823 Male, age 76, right hemisphere 1044.9
2227 Male, age 72, unknown 941.5
2769 Male, age 72, unknown 939.1
2725 Female, age 75, unknown 866.4
2785 Male, age 18, unknown 847.2
2588 Male, age 74, left hemisphere 789.4
2584 Male, age 75, left hemisphere 506.5
Substantia nigra
nTPM: 568.5
2241 Male, age 72, unknown 711.5
1851 Male, age 51, unknown 697.1
2409 Female, age 72, unknown 681.8
1916 Female, age 42, unknown 642.6
1889 Female, age 72, unknown 573.6
2590 Female, age 75, unknown 572.7
2699 Male, age 18, unknown 520.4
1941 Male, age 53, unknown 459.5
2583 Male, age 75, right hemisphere 428.3
2665 Male, age 74, both hemispheres 397.8
Superior colliculus
nTPM: 479.1
1895 Male, age 76, right hemisphere 761.0
2668 Female, age 75, unknown 601.3
2587 Male, age 74, left hemisphere 596.3
1839 Male, age 51, unknown 521.8
1995 Male, age 72, unknown 500.4
1913 Female, age 42, unknown 425.5
1796 Male, age 53, unknown 422.6
2261 Male, age 18, unknown 342.0
2087 Female, age 72, unknown 322.9
2664 Male, age 75, both hemispheres 296.8
Ventral tegmental area
nTPM: 521.4
2410 Female, age 72, unknown 858.3
1915 Female, age 42, unknown 539.8
2218 Male, age 76, both hemispheres 487.3
1942 Male, age 51, unknown 466.0
2223 Female, age 72, unknown 457.9
2021 Male, age 53, unknown 318.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

707.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 707.1
Samples: 139

Max nTPM: 2778.8
Min nTPM: 183.1
Std nTPM: 329.5
Median nTPM: 647.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 2778.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 1954.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1432.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1321.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1270.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1248.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 1246.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 1206.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1179.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 1178.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 1177.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 1166.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1157.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 1091.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 1081.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1077.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1068.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 1061.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1050.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 1021.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 989.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 978.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 977.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 943.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 940.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 938.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 928.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 924.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 916.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 889.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 867.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 843.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 841.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 836.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 832.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 821.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 817.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 815.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 815.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 802.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 798.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 787.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 779.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 769.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 762.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 757.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 754.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 749.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 749.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 743.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 738.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 737.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 736.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 735.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 734.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 727.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 715.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 710.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 707.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 705.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 703.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 694.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 691.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 677.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 661.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 661.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 660.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 650.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 649.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 647.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 642.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 637.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 636.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 627.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 625.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 624.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 622.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 613.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 612.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 612.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 611.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 607.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 596.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 583.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 579.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 577.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 576.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 572.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 569.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 568.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 562.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 554.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 546.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 545.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 541.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 532.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 531.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 531.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 524.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 520.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 519.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 519.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 516.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 514.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 497.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 494.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 484.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 480.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 479.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 479.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 475.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 472.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 472.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 468.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 465.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 463.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 462.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 451.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 433.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 431.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 406.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 402.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 388.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 386.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 382.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 377.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 377.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 351.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 351.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 349.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 294.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 288.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 274.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 269.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 267.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 265.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 257.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 253.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 183.1
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

1132.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 1132.2
FF:10158-103A5 76 years, female 1132.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

303.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 303.2
Samples: 4

Max nTPM: 396.1
Min nTPM: 175.7
Sample A Female 396.1
Sample B Female 175.7
Sample C Male 261.1
Sample D Male 379.9
Midbrain
nTPM: 237.8
Samples: 4

Max nTPM: 323.4
Min nTPM: 150.9
Sample A Female 323.4
Sample B Female 295.0
Sample C Male 150.9
Sample D Male 181.8
Periaqueductal gray
nTPM: 225.3
Samples: 3

Max nTPM: 230.3
Min nTPM: 216.6
Sample B Female 228.9
Sample C Male 216.6
Sample D Male 230.3
Superior colliculi
nTPM: 220.2
Samples: 4

Max nTPM: 294.6
Min nTPM: 106.6
Sample A Female 294.6
Sample B Female 106.6
Sample C Male 215.5
Sample D Male 264.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

480.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 480.9
Samples: 4

Max nTPM: 561.3
Min nTPM: 404.1
Sample A Male 561.3
Sample B Male 471.2
Sample C Female 404.1
Sample D Female 487.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

13.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 13.4
75042261 Antisense, RP_060412_02_D03, Mouse strain C57BL/6J (56 days, male) 15.3
631703 Antisense, RP_040907_01_A03, Mouse strain C57BL/6J (56 days, male) 11.5

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