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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:310.4 nTPM
HPA Brain:276.1 nTPM
GTEx:310.4 nTPM
FANTOM5:138.4 Scaled Tags Per Million
Pig:103.8 nTPM
Mouse:798.8 nTPM
Allen mouse:12.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

276.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 174.2
2219 Male, age 76, both hemispheres 228.1
1827 Male, age 72, unknown 198.3
2019 Male, age 18, unknown 198.1
2411 Female, age 72, unknown 196.3
2828 Female, age 72, unknown 170.8
1833 Male, age 53, unknown 166.8
1870 Female, age 42, unknown 165.3
2666 Male, age 74, left hemisphere 141.5
1830 Male, age 51, unknown 141.0
2586 Male, age 75, left hemisphere 135.8
Dorsal raphe nucleus
nTPM: 205.6
2298 Female, age 72, unknown 253.6
1828 Male, age 53, unknown 237.9
2047 Male, age 72, unknown 199.5
2750 Male, age 76, both hemispheres 171.2
2016 Female, age 72, unknown 165.6
Inferior colliculus
nTPM: 207.9
2097 Female, age 72, unknown 249.5
1890 Male, age 53, unknown 214.8
1848 Female, age 42, unknown 201.6
2849 Male, age 72, unknown 165.7
Median raphe nucleus
nTPM: 176.3
2220 Male, age 76, midline 176.3
Periaquaductal grey, anterior
nTPM: 179.3
1947 Male, age 18, unknown 203.4
1795 Male, age 51, unknown 172.9
2502 Female, age 75, unknown 161.6
Periaquaductal grey, dorsal
nTPM: 162.1
1840 Male, age 53, unknown 185.6
2464 Female, age 72, unknown 155.3
1831 Male, age 72, unknown 155.1
2850 Male, age 76, both hemispheres 152.5
Periaquaductal grey, lateral
nTPM: 167.4
2272 Male, age 74, both hemispheres 209.4
2053 Male, age 18, unknown 147.5
2140 Male, age 76, both hemispheres 145.3
Pretectal area
nTPM: 210.7
1816 Male, age 51, unknown 262.5
1944 Female, age 72, unknown 254.7
2667 Female, age 75, unknown 251.3
1817 Female, age 42, unknown 249.4
2007 Male, age 72, unknown 245.1
2273 Male, age 74, both hemispheres 215.7
1815 Male, age 53, unknown 201.8
2224 Female, age 72, unknown 188.5
2316 Male, age 76, right hemisphere 168.7
2825 Male, age 18, unknown 158.1
2407 Male, age 75, both hemispheres 121.5
Red nucleus
nTPM: 184.4
1821 Female, age 72, unknown 276.4
2725 Female, age 75, unknown 222.7
1954 Female, age 42, unknown 197.6
2503 Female, age 72, unknown 188.9
2823 Male, age 76, right hemisphere 183.1
2785 Male, age 18, unknown 177.3
2769 Male, age 72, unknown 176.7
2227 Male, age 72, unknown 175.4
1904 Male, age 53, unknown 174.9
1865 Male, age 51, unknown 169.7
2588 Male, age 74, left hemisphere 144.5
2584 Male, age 75, left hemisphere 125.4
Substantia nigra
nTPM: 276.1
1916 Female, age 42, unknown 420.5
2241 Male, age 72, unknown 352.5
1851 Male, age 51, unknown 324.4
1889 Female, age 72, unknown 270.2
2409 Female, age 72, unknown 264.9
1941 Male, age 53, unknown 261.5
2699 Male, age 18, unknown 260.9
2665 Male, age 74, both hemispheres 259.2
2590 Female, age 75, unknown 203.1
2583 Male, age 75, right hemisphere 143.5
Superior colliculus
nTPM: 174.2
2087 Female, age 72, unknown 234.3
1895 Male, age 76, right hemisphere 220.1
2261 Male, age 18, unknown 196.3
1796 Male, age 53, unknown 195.3
2587 Male, age 74, left hemisphere 180.8
2668 Female, age 75, unknown 164.0
1839 Male, age 51, unknown 157.9
1913 Female, age 42, unknown 134.9
1995 Male, age 72, unknown 129.8
2664 Male, age 75, both hemispheres 128.5
Ventral tegmental area
nTPM: 227.3
1915 Female, age 42, unknown 295.2
2410 Female, age 72, unknown 281.2
2218 Male, age 76, both hemispheres 277.9
1942 Male, age 51, unknown 203.5
2223 Female, age 72, unknown 156.2
2021 Male, age 53, unknown 149.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

310.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 310.4
Samples: 139

Max nTPM: 681.0
Min nTPM: 118.8
Std nTPM: 111.3
Median nTPM: 307.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 681.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 665.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 650.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 624.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 558.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 553.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 549.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 541.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 484.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 477.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 474.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 468.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 456.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 445.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 441.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 440.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 434.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 423.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 422.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 420.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 419.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 410.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 406.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 404.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 393.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 388.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 379.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 379.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 379.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 376.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 369.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 367.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 363.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 361.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 361.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 360.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 359.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 355.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 355.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 355.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 355.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 353.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 352.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 352.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 352.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 351.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 349.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 343.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 343.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 339.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 331.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 330.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 329.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 327.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 327.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 326.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 325.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 322.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 320.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 317.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 316.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 315.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 314.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 311.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 311.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 309.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 308.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 308.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 307.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 307.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 306.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 304.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 292.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 292.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 292.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 288.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 286.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 284.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 282.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 281.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 279.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 277.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 272.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 271.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 271.6
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 266.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 265.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 261.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 260.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 259.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 253.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 252.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 252.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 250.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 248.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 248.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 246.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 242.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 241.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 238.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 235.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 235.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 231.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 230.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 228.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 227.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 226.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 224.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 223.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 222.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 220.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 219.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 215.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 215.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 211.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 209.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 209.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 201.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 200.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 199.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 197.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 194.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 191.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 191.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 189.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 185.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 181.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 181.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 156.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 155.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 152.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 146.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 145.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 145.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 143.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 141.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 128.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 121.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 118.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

138.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 138.4
FF:10158-103A5 76 years, female 138.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

103.8
Pig sample Sample description nTPM
Substantia nigra
nTPM: 80.8
Samples: 4

Max nTPM: 108.4
Min nTPM: 63.2
Sample A Female 108.4
Sample B Female 67.2
Sample C Male 84.4
Sample D Male 63.2
Midbrain
nTPM: 90.4
Samples: 4

Max nTPM: 113.7
Min nTPM: 76.5
Sample A Female 84.8
Sample B Female 76.5
Sample C Male 113.7
Sample D Male 86.6
Periaqueductal gray
nTPM: 72.1
Samples: 3

Max nTPM: 79.1
Min nTPM: 62.3
Sample B Female 74.9
Sample C Male 79.1
Sample D Male 62.3
Superior colliculi
nTPM: 103.8
Samples: 4

Max nTPM: 125.9
Min nTPM: 85.5
Sample A Female 118.3
Sample B Female 85.5
Sample C Male 125.9
Sample D Male 85.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

798.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 798.8
Samples: 4

Max nTPM: 815.8
Min nTPM: 768.7
Sample A Male 815.8
Sample B Male 800.0
Sample C Female 768.7
Sample D Female 810.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

12.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 12.3
1579 Antisense, RP_040526_01_D04, Mouse strain C57BL/6J (56 days, male) 12.3
1580 Antisense, RP_040526_01_D04, Mouse strain C57BL/6J (56 days, male) 10.9

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