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EIF4A2
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  • EIF4A2
BRAIN PONS AND MEDULLA Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
PONS AND MEDULLA - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
HPA Brain:278.3 nTPM
FANTOM5:824.8 Scaled Tags Per Million
Mouse:878.1 nTPM
Allen mouse:15.6 Expression energy

PONS AND MEDULLA - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

278.3
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 159.1
2188 Female, age 91, both hemispheres 173.4
1984 Male, age 76, both hemispheres 172.1
2090 Male, age 80, both hemispheres 157.7
2301 Female, age 85, both hemispheres 133.5
Area postrema
nTPM: 119.8
2799 Male, age 61, both hemispheres 132.3
2306 Male, age 80, both hemispheres 119.5
2054 Male, age 76, both hemispheres 107.7
Dorsal cochlear nucleus
nTPM: 161.6
2187 Female, age 91, both hemispheres 197.8
2802 Male, age 74, right hemisphere 189.2
2370 Male, age 61, both hemispheres 144.3
2378 Male, age 80, both hemispheres 139.0
2058 Male, age 76, both hemispheres 137.9
Dorsal medullary reticular nucleus
nTPM: 165.9
2040 Female, age 85, both hemispheres 236.4
2373 Male, age 61, both hemispheres 147.1
2088 Male, age 76, both hemispheres 114.4
Dorsal motor vagal complex
nTPM: 146.2
2133 Female, age 91, both hemispheres 226.2
2000 Male, age 74, unknown 178.8
2813 Female, age 72, unknown 172.9
2844 Male, age 55, unknown 169.6
2643 Male, age 74, both hemispheres 137.6
2797 Male, age 61, both hemispheres 108.8
2185 Male, age 76, both hemispheres 90.9
2807 Female, age 85, both hemispheres 84.8
Dorsal tegmental nucleus
nTPM: 169.1
2326 Male, age 74, both hemispheres 207.2
2083 Male, age 80, both hemispheres 201.6
1936 Male, age 76, left hemisphere 137.1
2358 Male, age 61, both hemispheres 130.6
Dorsolateral tegmental area
nTPM: 181.6
2751 Female, age 85, both hemispheres 210.3
2654 Male, age 80, both hemispheres 196.5
2360 Male, age 74, both hemispheres 181.8
2141 Male, age 76, both hemispheres 162.6
2337 Male, age 61, both hemispheres 156.9
Gigantocellular reticular nuclei, medullary
nTPM: 191.8
2462 Male, age 74, both hemispheres 230.2
1876 Female, age 85, both hemispheres 224.5
2022 Male, age 76, right hemisphere 210.6
2314 Male, age 61, both hemispheres 170.6
2387 Female, age 91, both hemispheres 165.4
2310 Male, age 80, both hemispheres 149.4
Gigantocellular reticular nuclei, pars
nTPM: 174.7
2168 Male, age 76, both hemispheres 280.9
2084 Female, age 85, both hemispheres 191.2
2336 Male, age 61, both hemispheres 160.4
2706 Male, age 80, both hemispheres 123.4
2330 Male, age 80, both hemispheres 117.7
Inferior olive
nTPM: 147.9
2563 Male, age 74, both hemispheres 181.4
2178 Male, age 61, both hemispheres 170.9
2628 Female, age 91, both hemispheres 138.8
2085 Female, age 85, both hemispheres 124.4
2379 Male, age 80, both hemispheres 124.2
Kolliker-Fuse nucleus
nTPM: 192.1
2163 Male, age 80, both hemispheres 212.4
2315 Male, age 76, right hemisphere 202.2
2793 Female, age 91, left hemisphere 161.7
Lateral lemniscal nuclei
nTPM: 226.8
2169 Male, age 76, both hemispheres 325.2
2746 Female, age 85, left hemisphere 273.9
2036 Male, age 80, both hemispheres 201.7
2453 Male, age 74, right hemisphere 190.7
2320 Female, age 91, left hemisphere 142.5
Lateral medullary reticular nucleus
nTPM: 168.8
2044 Male, age 76, both hemispheres 216.9
2305 Male, age 74, both hemispheres 188.8
2804 Female, age 91, both hemispheres 166.4
2374 Male, age 61, both hemispheres 158.9
2190 Female, age 85, both hemispheres 150.2
2852 Male, age 80, both hemispheres 131.8
Lateral parabrachial nucleus
nTPM: 187.6
2139 Female, age 85, right hemisphere 283.4
2013 Male, age 80, both hemispheres 196.9
2792 Male, age 76, both hemispheres 137.1
2790 Male, age 61, both hemispheres 132.9
Lateral vestibular nucleus
nTPM: 170.6
2311 Male, age 80, both hemispheres 172.0
2184 Male, age 76, both hemispheres 169.3
Locus coeruleus
nTPM: 212.5
2123 Female, age 91, both hemispheres 263.7
2014 Male, age 55, unknown 243.0
2788 Male, age 74, unknown 238.7
2720 Male, age 74, both hemispheres 231.7
2317 Female, age 72, unknown 182.4
2162 Male, age 80, both hemispheres 174.6
1980 Male, age 76, both hemispheres 153.4
Medial olivary nucleus
nTPM: 164.4
1943 Male, age 61, both hemispheres 200.9
2138 Female, age 91, both hemispheres 164.3
1962 Male, age 76, both hemispheres 149.1
2851 Male, age 80, both hemispheres 143.2
Medial parabrachial nucleus
nTPM: 185.6
2170 Female, age 91, both hemispheres 252.2
2854 Male, age 80, both hemispheres 213.7
2463 Female, age 85, right hemisphere 159.3
2786 Male, age 76, both hemispheres 159.3
2156 Male, age 61, both hemispheres 143.2
Medial periolivary nuclei
nTPM: 230.7
2063 Male, age 76, both hemispheres 336.8
2171 Female, age 85, both hemispheres 327.8
2791 Male, age 74, right hemisphere 219.9
2081 Male, age 80, both hemispheres 140.4
2458 Female, age 91, both hemispheres 128.7
Medial vestibular nucleus
nTPM: 207.6
2803 Female, age 91, both hemispheres 252.5
2801 Male, age 74, both hemispheres 233.8
2743 Female, age 85, both hemispheres 206.8
2093 Male, age 80, both hemispheres 203.3
2134 Male, age 76, both hemispheres 194.0
2624 Male, age 61, both hemispheres 154.9
Motor facial nucleus
nTPM: 207.6
2062 Male, age 76, both hemispheres 324.9
2365 Male, age 74, right hemisphere 245.5
2697 Female, age 85, both hemispheres 198.1
2795 Female, age 91, both hemispheres 181.8
2126 Male, age 61, both hemispheres 155.7
2327 Male, age 80, both hemispheres 139.9
Motor hypoglossal nucleus
nTPM: 167.5
2125 Female, age 91, both hemispheres 235.1
2132 Female, age 85, both hemispheres 202.3
2461 Male, age 61, both hemispheres 161.4
2182 Male, age 80, both hemispheres 138.2
2277 Male, age 76, both hemispheres 100.6
Motor trigeminal nucleus
nTPM: 161.2
2079 Male, age 80, both hemispheres 185.3
2309 Male, age 76, both hemispheres 176.5
2560 Male, age 74, both hemispheres 159.9
2335 Male, age 61, both hemispheres 154.3
2321 Female, age 91, both hemispheres 130.2
Nuclei of the trapezoid body
nTPM: 241.3
1983 Male, age 76, both hemispheres 361.5
2735 Female, age 85, both hemispheres 322.4
2159 Male, age 61, both hemispheres 243.6
2166 Male, age 80, both hemispheres 160.1
2368 Female, age 91, both hemispheres 119.0
Nucleus ambiguus
nTPM: 130.2
2096 Female, age 85, both hemispheres 133.0
2071 Male, age 76, both hemispheres 127.4
Nucleus cuneatus
nTPM: 127.0
2376 Male, age 61, both hemispheres 162.4
2564 Male, age 74, both hemispheres 159.9
2381 Male, age 80, both hemispheres 132.9
2131 Male, age 76, both hemispheres 131.8
2562 Male, age 61, both hemispheres 129.7
2380 Male, age 80, both hemispheres 127.8
2805 Female, age 91, both hemispheres 111.2
2100 Male, age 76, both hemispheres 97.0
2808 Female, age 85, both hemispheres 90.5
Nucleus gracilis
nTPM: 129.3
2627 Male, age 74, both hemispheres 193.5
2382 Male, age 80, both hemispheres 120.7
2299 Female, age 85, both hemispheres 73.6
Nucleus raphe magnus
nTPM: 246.5
2160 Male, age 61, both hemispheres 359.8
2172 Female, age 85, both hemispheres 320.2
2455 Male, age 74, both hemispheres 275.7
2051 Male, age 76, both hemispheres 216.9
2328 Male, age 80, both hemispheres 158.5
2459 Female, age 91, both hemispheres 147.9
Nucleus raphe obscurus
nTPM: 159.2
2845 Female, age 85, midline 195.7
2800 Male, age 61, midline 186.0
2142 Male, age 76, midline 96.0
Nucleus raphe pallidus
nTPM: 188.6
1924 Male, age 61, midline 257.5
2183 Male, age 80, midline 203.4
2145 Male, age 76, midline 104.8
Nucleus tractus solitarii
nTPM: 155.2
2144 Female, age 91, right hemisphere 288.9
2656 Male, age 76, both hemispheres 131.1
2191 Female, age 85, both hemispheres 102.1
2307 Male, age 80, both hemispheres 98.6
Paramedian reticular nucleus
nTPM: 219.3
2050 Female, age 85, both hemispheres 294.6
2057 Male, age 80, both hemispheres 196.8
2313 Male, age 61, both hemispheres 195.0
2052 Male, age 76, both hemispheres 190.7
Parvicellular reticular nuclei
nTPM: 178.5
2095 Male, age 76, both hemispheres 192.1
2119 Male, age 80, both hemispheres 182.8
2558 Male, age 74, both hemispheres 160.5
Parvicellular reticular nuclei, medullary
nTPM: 203.7
2189 Female, age 91, both hemispheres 244.1
2181 Male, age 80, left hemisphere 184.9
2091 Female, age 85, both hemispheres 182.1
Pedunculopontine tegmental nucleus
nTPM: 197.0
1921 Female, age 85, both hemispheres 208.2
2334 Male, age 80, both hemispheres 197.3
2338 Male, age 61, both hemispheres 185.6
Peritrigeminal nucleus
nTPM: 195.9
2136 Male, age 76, both hemispheres 210.4
2179 Male, age 61, both hemispheres 193.4
2067 Female, age 85, both hemispheres 183.8
Pontine nuclei
nTPM: 278.3
2787 Female, age 85, both hemispheres 440.6
2727 Male, age 61, right hemisphere 369.2
1863 Male, age 55, unknown 358.4
1968 Male, age 76, left hemisphere 276.4
2109 Female, age 72, unknown 256.9
2454 Male, age 74, left hemisphere 211.5
2319 Female, age 91, both hemispheres 187.6
2115 Male, age 80, left hemisphere 126.3
Pontine raphe nucleus
nTPM: 250.6
2122 Female, age 85, midline 325.5
2853 Male, age 76, midline 175.7
Posteroventral cochlear nucleus
nTPM: 175.9
2752 Female, age 85, both hemispheres 224.4
2070 Male, age 76, both hemispheres 180.2
2341 Male, age 80, both hemispheres 162.5
2135 Female, age 91, both hemispheres 157.5
2371 Male, age 61, both hemispheres 154.8
Prepositus hypoglossal nucleus
nTPM: 177.3
2855 Female, age 85, right hemisphere 193.9
2086 Male, age 80, both hemispheres 160.7
Principal sensory trigeminal nucleus
nTPM: 198.3
2158 Male, age 61, both hemispheres 256.8
2008 Male, age 80, left hemisphere 223.2
2367 Female, age 91, left hemisphere 159.8
2324 Male, age 76, both hemispheres 153.4
Reticular pontine nucleus, caudal
nTPM: 185.0
2092 Male, age 76, both hemispheres 280.3
2559 Male, age 74, both hemispheres 176.6
2457 Female, age 91, both hemispheres 146.4
2332 Male, age 80, right hemisphere 136.7
Reticular pontine nucleus, oral
nTPM: 224.2
2361 Male, age 74, both hemispheres 292.6
2012 Female, age 85, both hemispheres 285.6
1939 Male, age 80, both hemispheres 210.1
2167 Male, age 76, both hemispheres 178.3
2366 Female, age 91, both hemispheres 154.2
Reticulotegmental nucleus
nTPM: 180.2
2325 Male, age 76, both hemispheres 224.1
2452 Male, age 74, both hemispheres 187.9
2322 Female, age 91, both hemispheres 159.0
2333 Male, age 80, both hemispheres 149.9
Spinal trigeminal nucleus, caudal
nTPM: 167.0
2390 Female, age 91, both hemispheres 238.9
2312 Male, age 61, both hemispheres 170.5
2642 Male, age 74, both hemispheres 147.3
2308 Male, age 80, both hemispheres 140.0
2447 Male, age 76, both hemispheres 138.4
Spinal trigeminal nucleus, interpolar
nTPM: 219.3
2066 Male, age 76, right hemisphere 298.6
2625 Male, age 61, both hemispheres 204.9
2386 Female, age 85, both hemispheres 200.3
2389 Female, age 91, both hemispheres 199.0
2033 Male, age 80, both hemispheres 193.4
Spinal trigeminal nucleus, oral
nTPM: 182.6
2737 Female, age 85, both hemispheres 214.6
2164 Male, age 80, both hemispheres 167.3
1978 Male, age 76, both hemispheres 165.7
Spinal vestibular nucleus
nTPM: 201.6
2186 Female, age 91, both hemispheres 233.2
2806 Female, age 85, both hemispheres 219.6
2780 Male, age 80, both hemispheres 214.6
2748 Male, age 76, both hemispheres 190.5
2384 Male, age 74, both hemispheres 180.5
2796 Male, age 61, both hemispheres 171.1
Subcoeruleus area
nTPM: 199.8
1958 Male, age 80, both hemispheres 241.6
2323 Female, age 91, left hemisphere 221.4
2089 Male, age 76, left hemisphere 193.3
2369 Female, age 85, left hemisphere 177.9
2451 Male, age 74, both hemispheres 164.9
Superior olive
nTPM: 234.7
1875 Female, age 85, both hemispheres 379.0
2020 Male, age 76, both hemispheres 264.3
2364 Male, age 74, right hemisphere 260.5
2329 Male, age 80, right hemisphere 139.1
2561 Female, age 91, both hemispheres 130.5
Superior vestibular nucleus
nTPM: 200.5
2383 Male, age 74, both hemispheres 260.1
2015 Male, age 80, both hemispheres 205.1
2061 Male, age 76, both hemispheres 136.2
Ventral medullary reticular nucleus
nTPM: 164.9
2372 Male, age 61, both hemispheres 165.6
2060 Male, age 76, both hemispheres 164.3
Ventral periolivary nuclei
nTPM: 234.4
2130 Female, age 85, both hemispheres 290.6
2023 Male, age 76, both hemispheres 275.1
2165 Male, age 80, both hemispheres 223.9
2794 Female, age 91, left hemisphere 148.0
Ventrolateral medulla, A1-C1 cell groups
nTPM: 183.9
1986 Male, age 76, both hemispheres 219.6
2741 Female, age 85, both hemispheres 211.1
2180 Male, age 61, both hemispheres 195.5
2302 Female, age 91, both hemispheres 154.2
2118 Male, age 80, both hemispheres 139.2
Ventrolateral tegmental area, A5 NE cell group
nTPM: 199.6
1959 Male, age 76, both hemispheres 254.4
2840 Female, age 85, both hemispheres 235.7
2449 Male, age 74, both hemispheres 217.0
2359 Male, age 61, both hemispheres 187.6
2161 Male, age 80, both hemispheres 172.9
2456 Female, age 91, both hemispheres 130.2

PONS AND MEDULLA - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

824.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 527.9
FF:10182-103D2 60 years, female 568.5
FF:10165-103B3 76 years, female 487.3
Medulla oblongata
Scaled Tags Per Million: 472.4
FF:10174-103C3 60 years, female 550.3
FF:10155-103A2 76 years, female 444.0
FF:10038-101F2 18-64 years, mixed 423.0
Pons
Scaled Tags Per Million: 824.8
FF:10033-101E6 18-54 years, mixed 824.8

PONS AND MEDULLA - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

878.1
Mouse sample Sample description nTPM
Pons and medulla
nTPM: 878.1
Samples: 4

Max nTPM: 905.9
Min nTPM: 853.3
Sample A Male 853.3
Sample B Male 897.9
Sample C Female 855.1
Sample D Female 905.9

PONS AND MEDULLA - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

15.6
Allen experiment id Experiment description Expression energy
Medulla oblongata
Expression energy: 15.6
71381013 Antisense, RP_050428_02_F12, Mouse strain C57BL/6J (56 days, male) 15.6
Pons
Expression energy: 15.4
71381013 Antisense, RP_050428_02_F12, Mouse strain C57BL/6J (56 days, male) 15.4

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