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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Medium
Hepatocytes:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
129.1
nTPM
HPA:
30.4
nTPM
GTEx:
129.1
nTPM
FANTOM5:
71.4
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA046615
Cholangiocytes
Medium
Hepatocytes
Medium
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
30.4
Female, age 60
Liver sample 21 nTPM: 63
Male, age 54
Liver sample 23 nTPM: 41.5
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 48.6
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 7.1
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 7.2
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 18.1
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 14.3
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 53.3
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 18.9
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 32.1
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
129.1
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 129.1
Samples: 226
Max nTPM: 278.8
Min nTPM: 45.3
Std nTPM: 37.6
Median nTPM: 121.8
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
278.8
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
278.3
GTEX-14PJO-1726-SM-68719
60-69 years, male
259.8
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
253.8
GTEX-REY6-1226-SM-48FDR
60-69 years, male
229.5
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
210.8
GTEX-11ZUS-2526-SM-59872
30-39 years, male
210.6
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
203.7
GTEX-13113-1326-SM-5GCOI
60-69 years, female
202.4
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
202.4
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
200.9
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
199.9
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
198.5
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
196.7
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
192.9
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
192.6
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
190.7
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
189.8
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
187.8
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
180.7
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
180.0
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
176.4
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
173.7
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
170.1
GTEX-S33H-1626-SM-4AD68
30-39 years, male
169.8
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
169.8
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
168.8
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
168.2
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
166.7
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
166.0
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
165.2
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
163.2
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
162.5
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
161.6
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
160.9
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
160.8
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
160.1
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
159.9
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
159.6
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
159.6
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
159.2
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
159.0
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
158.2
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
157.9
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
156.6
GTEX-QESD-2026-SM-447BI
20-29 years, male
156.3
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
156.2
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
155.9
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
154.7
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
154.4
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
154.3
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
154.1
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
153.9
GTEX-O5YV-0726-SM-EV798
60-69 years, female
153.7
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
152.9
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
151.4
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
150.9
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
150.6
GTEX-P78B-1326-SM-3P611
40-49 years, female
150.5
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
149.5
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
148.8
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
148.5
GTEX-RU72-1426-SM-46MUF
50-59 years, female
146.6
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
146.1
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
145.5
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
144.9
GTEX-R53T-0326-SM-48FEC
50-59 years, female
143.7
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
140.9
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
140.7
GTEX-1B932-1426-SM-793AN
40-49 years, female
139.7
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
139.6
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
139.6
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
139.2
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
139.2
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
139.1
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
138.8
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
138.8
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
138.7
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
137.6
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
137.5
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
137.2
GTEX-14JG1-1626-SM-664NH
40-49 years, male
136.3
GTEX-QEL4-1226-SM-447A4
50-59 years, male
135.3
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
135.0
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
135.0
GTEX-12696-0826-SM-5EGGE
60-69 years, male
134.8
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
134.8
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
134.3
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
134.2
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
133.7
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
133.4
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
133.3
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
132.4
GTEX-X261-1726-SM-4PQYT
50-59 years, male
132.4
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
132.2
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
131.9
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
131.8
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
130.6
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
130.1
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
130.0
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
129.9
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
129.4
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
127.7
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
126.6
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
126.3
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
126.3
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
124.0
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
123.8
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
123.7
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
123.1
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
122.7
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
121.9
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
121.9
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
121.8
GTEX-S32W-1926-SM-4AD63
50-59 years, female
121.6
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
120.7
GTEX-14XAO-0226-SM-68728
60-69 years, female
120.5
GTEX-Q734-0326-SM-48U15
40-49 years, female
119.6
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
119.5
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
119.4
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
119.1
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
118.8
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
118.6
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
118.5
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
117.9
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
117.4
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
116.7
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
116.7
GTEX-18A66-2026-SM-7189C
60-69 years, male
116.5
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
116.3
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
116.3
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
115.4
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
115.1
GTEX-14PHX-0526-SM-664NW
50-59 years, male
114.9
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
114.7
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
114.6
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
114.5
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
113.7
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
113.2
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
113.0
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
112.8
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
112.8
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
112.7
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
111.9
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
110.9
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
110.6
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
110.6
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
110.6
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
109.8
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
109.6
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
109.3
GTEX-18A7A-1526-SM-72D69
50-59 years, female
108.3
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
107.7
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
107.6
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
107.5
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
107.0
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
106.1
GTEX-18465-1626-SM-7LG6N
50-59 years, male
105.4
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
105.2
GTEX-14E7W-1526-SM-6871X
70-79 years, male
104.8
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
104.6
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
103.9
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
103.8
GTEX-YECK-1926-SM-4W21H
60-69 years, male
103.7
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
103.0
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
103.0
GTEX-1B933-1226-SM-731DW
50-59 years, female
102.8
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
102.8
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
102.2
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
102.2
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
101.4
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
101.3
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
101.0
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
100.4
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
100.4
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
100.2
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
100.2
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
100.1
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
100.0
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
99.6
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
99.4
GTEX-RN64-1826-SM-48FDV
50-59 years, male
98.6
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
98.3
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
98.1
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
97.6
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
97.4
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
96.8
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
96.6
GTEX-144GL-1426-SM-79OMA
50-59 years, male
96.3
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
95.6
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
95.0
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
94.8
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
94.7
GTEX-17HHE-0126-SM-79398
50-59 years, male
94.2
GTEX-17F96-1226-SM-79OK2
70-79 years, male
93.3
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
93.2
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
92.9
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
92.7
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
91.2
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
90.9
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
90.4
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
90.1
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
89.8
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
89.6
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
89.2
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
89.2
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
88.1
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
87.9
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
87.2
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
87.2
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
85.5
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
85.4
GTEX-1399T-0826-SM-5IFES
60-69 years, male
85.1
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
83.9
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
83.8
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
82.3
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
81.4
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
80.2
GTEX-13112-1426-SM-5EGH8
50-59 years, male
77.7
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
75.5
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
73.9
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
73.4
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
72.1
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
63.2
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
45.9
GTEX-11GSP-0626-SM-5986T
60-69 years, female
45.3
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
