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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:1774.3 nTPM
HPA Brain:456.9 nTPM
GTEx:1774.3 nTPM
FANTOM5:120.0 Scaled Tags Per Million
Pig:342.6 nTPM
Mouse:1600.8 nTPM
Allen mouse:12.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

456.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 386.9
2666 Male, age 74, left hemisphere 483.4
1870 Female, age 42, unknown 428.1
1833 Male, age 53, unknown 403.4
2411 Female, age 72, unknown 397.2
1827 Male, age 72, unknown 386.4
1830 Male, age 51, unknown 386.2
2219 Male, age 76, both hemispheres 374.4
2828 Female, age 72, unknown 361.2
2019 Male, age 18, unknown 335.9
2586 Male, age 75, left hemisphere 313.0
Dorsal raphe nucleus
nTPM: 363.8
2750 Male, age 76, both hemispheres 429.3
2298 Female, age 72, unknown 378.7
2016 Female, age 72, unknown 377.8
1828 Male, age 53, unknown 361.5
2047 Male, age 72, unknown 271.8
Inferior colliculus
nTPM: 397.1
2849 Male, age 72, unknown 449.1
1890 Male, age 53, unknown 396.4
2097 Female, age 72, unknown 379.0
1848 Female, age 42, unknown 364.0
Median raphe nucleus
nTPM: 405.5
2220 Male, age 76, midline 405.5
Periaquaductal grey, anterior
nTPM: 377.6
2502 Female, age 75, unknown 416.8
1795 Male, age 51, unknown 358.7
1947 Male, age 18, unknown 357.4
Periaquaductal grey, dorsal
nTPM: 377.4
2850 Male, age 76, both hemispheres 392.9
1840 Male, age 53, unknown 386.5
1831 Male, age 72, unknown 381.9
2464 Female, age 72, unknown 348.3
Periaquaductal grey, lateral
nTPM: 347.5
2053 Male, age 18, unknown 377.6
2140 Male, age 76, both hemispheres 346.5
2272 Male, age 74, both hemispheres 318.4
Pretectal area
nTPM: 377.1
1815 Male, age 53, unknown 445.4
1816 Male, age 51, unknown 422.5
2825 Male, age 18, unknown 421.4
1817 Female, age 42, unknown 418.4
2316 Male, age 76, right hemisphere 391.8
2224 Female, age 72, unknown 377.0
2007 Male, age 72, unknown 371.7
1944 Female, age 72, unknown 357.3
2667 Female, age 75, unknown 333.4
2407 Male, age 75, both hemispheres 315.9
2273 Male, age 74, both hemispheres 293.0
Red nucleus
nTPM: 430.9
2503 Female, age 72, unknown 533.1
1821 Female, age 72, unknown 502.0
2725 Female, age 75, unknown 493.7
1865 Male, age 51, unknown 463.2
2584 Male, age 75, left hemisphere 446.4
2588 Male, age 74, left hemisphere 410.6
2227 Male, age 72, unknown 408.3
2823 Male, age 76, right hemisphere 406.7
1904 Male, age 53, unknown 403.2
2769 Male, age 72, unknown 389.6
1954 Female, age 42, unknown 357.9
2785 Male, age 18, unknown 356.6
Substantia nigra
nTPM: 456.9
2699 Male, age 18, unknown 577.6
2665 Male, age 74, both hemispheres 541.3
2241 Male, age 72, unknown 538.3
2409 Female, age 72, unknown 524.4
1851 Male, age 51, unknown 511.9
1916 Female, age 42, unknown 413.9
1889 Female, age 72, unknown 396.6
2590 Female, age 75, unknown 387.8
1941 Male, age 53, unknown 361.5
2583 Male, age 75, right hemisphere 315.4
Superior colliculus
nTPM: 410.9
2587 Male, age 74, left hemisphere 510.1
1913 Female, age 42, unknown 488.1
1995 Male, age 72, unknown 449.7
2668 Female, age 75, unknown 413.8
1796 Male, age 53, unknown 409.0
1895 Male, age 76, right hemisphere 388.0
1839 Male, age 51, unknown 382.6
2261 Male, age 18, unknown 372.7
2087 Female, age 72, unknown 365.4
2664 Male, age 75, both hemispheres 329.6
Ventral tegmental area
nTPM: 434.4
2223 Female, age 72, unknown 537.1
1915 Female, age 42, unknown 475.0
2021 Male, age 53, unknown 437.5
2410 Female, age 72, unknown 410.7
2218 Male, age 76, both hemispheres 403.3
1942 Male, age 51, unknown 342.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1774.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 1774.3
Samples: 139

Max nTPM: 4652.2
Min nTPM: 662.9
Std nTPM: 677.3
Median nTPM: 1679.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 4652.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 4562.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 4364.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 3983.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 3051.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 3003.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 2998.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 2948.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 2912.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 2887.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 2843.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 2786.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 2780.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 2516.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 2469.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 2429.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 2427.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 2331.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 2329.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 2276.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 2264.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 2260.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 2251.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 2227.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 2226.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 2224.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 2211.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 2204.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 2173.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 2148.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 2142.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 2142.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 2079.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 2070.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 2067.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 2066.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 2046.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 2007.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1999.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 1962.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 1962.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 1917.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 1907.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1905.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 1872.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 1862.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1849.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 1838.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 1837.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 1816.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 1815.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 1813.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1799.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 1794.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 1779.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 1778.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 1773.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1769.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1764.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 1752.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1751.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 1749.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 1734.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 1729.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 1728.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1719.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1706.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 1700.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 1680.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1679.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 1668.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 1632.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 1616.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 1587.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 1587.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 1587.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1568.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 1554.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 1547.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1546.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 1524.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 1517.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 1513.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 1506.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1498.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 1493.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 1460.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 1438.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 1437.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 1431.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 1423.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 1406.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 1404.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 1391.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 1383.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 1366.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 1359.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 1358.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 1357.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 1346.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 1336.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 1331.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 1331.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 1323.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 1316.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 1313.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 1270.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 1258.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 1253.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 1244.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 1242.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 1224.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 1223.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1222.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 1221.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 1216.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1215.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 1209.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 1203.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 1196.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 1191.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 1175.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 1161.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 1159.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 1134.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 1134.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 1126.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 1120.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 1102.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 1075.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 1053.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 1044.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 1034.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 1021.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 998.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 886.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 878.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 870.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 662.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

120.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 120.0
FF:10158-103A5 76 years, female 120.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

342.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 318.8
Samples: 4

Max nTPM: 381.3
Min nTPM: 230.4
Sample A Female 380.4
Sample B Female 381.3
Sample C Male 282.9
Sample D Male 230.4
Midbrain
nTPM: 306.9
Samples: 4

Max nTPM: 385.7
Min nTPM: 233.5
Sample A Female 363.5
Sample B Female 385.7
Sample C Male 244.8
Sample D Male 233.5
Periaqueductal gray
nTPM: 257.1
Samples: 3

Max nTPM: 285.9
Min nTPM: 234.1
Sample B Female 285.9
Sample C Male 251.2
Sample D Male 234.1
Superior colliculi
nTPM: 342.6
Samples: 4

Max nTPM: 420.1
Min nTPM: 289.3
Sample A Female 353.9
Sample B Female 420.1
Sample C Male 307.2
Sample D Male 289.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1600.8
Mouse sample Sample description nTPM
Midbrain
nTPM: 1600.8
Samples: 4

Max nTPM: 1667.6
Min nTPM: 1544.0
Sample A Male 1667.6
Sample B Male 1588.3
Sample C Female 1544.0
Sample D Female 1603.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

12.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 12.1
69816792 Antisense, RP_050510_01_H06, Mouse strain C57BL/6J (56 days, male) 12.1

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