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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:108.0 nTPM
HPA Brain:55.8 nTPM
GTEx:108.0 nTPM
FANTOM5:140.9 Scaled Tags Per Million
Pig:71.5 nTPM
Mouse:104.6 nTPM
Allen mouse:6.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

55.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 51.4
2666 Male, age 74, left hemisphere 59.9
2586 Male, age 75, left hemisphere 54.7
2828 Female, age 72, unknown 54.5
1870 Female, age 42, unknown 53.9
1827 Male, age 72, unknown 52.1
2019 Male, age 18, unknown 50.5
2411 Female, age 72, unknown 50.1
1833 Male, age 53, unknown 49.4
1830 Male, age 51, unknown 45.2
2219 Male, age 76, both hemispheres 43.6
Dorsal raphe nucleus
nTPM: 46.0
2750 Male, age 76, both hemispheres 47.6
1828 Male, age 53, unknown 47.5
2016 Female, age 72, unknown 46.4
2298 Female, age 72, unknown 46.0
2047 Male, age 72, unknown 42.6
Inferior colliculus
nTPM: 45.3
2849 Male, age 72, unknown 48.7
1890 Male, age 53, unknown 46.4
1848 Female, age 42, unknown 43.4
2097 Female, age 72, unknown 42.7
Median raphe nucleus
nTPM: 46.9
2220 Male, age 76, midline 46.9
Periaquaductal grey, anterior
nTPM: 48.2
2502 Female, age 75, unknown 53.1
1795 Male, age 51, unknown 49.4
1947 Male, age 18, unknown 42.3
Periaquaductal grey, dorsal
nTPM: 43.5
2850 Male, age 76, both hemispheres 48.3
2464 Female, age 72, unknown 43.9
1831 Male, age 72, unknown 42.8
1840 Male, age 53, unknown 38.9
Periaquaductal grey, lateral
nTPM: 43.5
2140 Male, age 76, both hemispheres 48.9
2053 Male, age 18, unknown 43.3
2272 Male, age 74, both hemispheres 38.2
Pretectal area
nTPM: 46.7
1816 Male, age 51, unknown 52.4
1817 Female, age 42, unknown 50.5
2007 Male, age 72, unknown 50.5
2407 Male, age 75, both hemispheres 49.3
1815 Male, age 53, unknown 48.3
2825 Male, age 18, unknown 46.8
2667 Female, age 75, unknown 46.3
2224 Female, age 72, unknown 45.4
1944 Female, age 72, unknown 45.1
2316 Male, age 76, right hemisphere 40.3
2273 Male, age 74, both hemispheres 39.2
Red nucleus
nTPM: 55.8
2503 Female, age 72, unknown 62.3
1865 Male, age 51, unknown 61.5
2725 Female, age 75, unknown 59.2
1904 Male, age 53, unknown 57.9
1821 Female, age 72, unknown 57.8
2769 Male, age 72, unknown 56.8
2227 Male, age 72, unknown 55.9
2588 Male, age 74, left hemisphere 54.1
1954 Female, age 42, unknown 53.4
2785 Male, age 18, unknown 52.0
2584 Male, age 75, left hemisphere 51.5
2823 Male, age 76, right hemisphere 47.3
Substantia nigra
nTPM: 47.2
2699 Male, age 18, unknown 58.0
2665 Male, age 74, both hemispheres 55.4
1916 Female, age 42, unknown 52.6
1851 Male, age 51, unknown 50.0
1889 Female, age 72, unknown 48.6
1941 Male, age 53, unknown 47.2
2590 Female, age 75, unknown 45.7
2583 Male, age 75, right hemisphere 43.7
2241 Male, age 72, unknown 36.1
2409 Female, age 72, unknown 34.3
Superior colliculus
nTPM: 49.6
1995 Male, age 72, unknown 57.1
1913 Female, age 42, unknown 56.8
2587 Male, age 74, left hemisphere 54.7
1796 Male, age 53, unknown 50.4
2664 Male, age 75, both hemispheres 49.8
2261 Male, age 18, unknown 48.7
1895 Male, age 76, right hemisphere 47.8
1839 Male, age 51, unknown 45.0
2087 Female, age 72, unknown 43.1
2668 Female, age 75, unknown 43.0
Ventral tegmental area
nTPM: 49.3
2223 Female, age 72, unknown 53.7
1915 Female, age 42, unknown 53.4
2410 Female, age 72, unknown 48.8
2021 Male, age 53, unknown 48.0
2218 Male, age 76, both hemispheres 47.4
1942 Male, age 51, unknown 44.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

108.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 108.0
Samples: 139

Max nTPM: 237.9
Min nTPM: 54.5
Std nTPM: 26.3
Median nTPM: 104.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 237.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 190.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 182.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 167.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 163.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 159.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 156.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 153.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 153.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 153.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 152.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 149.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 139.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 136.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 136.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 135.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 131.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 131.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 131.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 130.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 130.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 130.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 129.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 127.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 126.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 126.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 125.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 125.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 124.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 124.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 123.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 123.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 122.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 121.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 120.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 120.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 119.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 118.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 117.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 116.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 116.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 115.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 115.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 114.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 114.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 113.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 113.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 113.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 113.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 113.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 113.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 112.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 112.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 112.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 111.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 110.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 109.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 109.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 109.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 108.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 108.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 108.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 107.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 106.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 106.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 105.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 105.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 105.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 105.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 104.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 104.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 104.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 103.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 103.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 103.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 102.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 102.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 102.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 101.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 101.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 100.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 99.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 99.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 99.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 98.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 98.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 98.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 98.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 97.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 97.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 96.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 96.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 96.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 95.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 95.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 94.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 94.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 93.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 93.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 92.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 91.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 90.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 90.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 90.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 90.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 90.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 88.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 88.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 88.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 88.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 87.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 87.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 86.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 86.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 86.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 86.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 86.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 85.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 85.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 85.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 83.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 83.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 81.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 80.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 80.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 79.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 79.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 78.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 77.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 77.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 76.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 75.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 73.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 72.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 69.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 68.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 60.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 58.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 54.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

140.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 140.9
FF:10158-103A5 76 years, female 140.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

71.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 69.5
Samples: 4

Max nTPM: 85.4
Min nTPM: 60.0
Sample A Female 85.4
Sample B Female 60.0
Sample C Male 67.1
Sample D Male 65.4
Midbrain
nTPM: 70.9
Samples: 4

Max nTPM: 105.9
Min nTPM: 49.9
Sample A Female 105.9
Sample B Female 68.8
Sample C Male 58.9
Sample D Male 49.9
Periaqueductal gray
nTPM: 55.6
Samples: 3

Max nTPM: 59.9
Min nTPM: 51.1
Sample B Female 55.8
Sample C Male 59.9
Sample D Male 51.1
Superior colliculi
nTPM: 71.5
Samples: 4

Max nTPM: 83.5
Min nTPM: 63.5
Sample A Female 83.5
Sample B Female 63.5
Sample C Male 72.8
Sample D Male 66.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

104.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 104.6
Samples: 4

Max nTPM: 119.8
Min nTPM: 90.4
Sample A Male 119.8
Sample B Male 102.1
Sample C Female 90.4
Sample D Female 106.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

6.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 6.3
71992097 Antisense, RP_051012_04_B07, Mouse strain C57BL/6J (56 days, male) 6.3

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