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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Low
Hepatocytes:
Low
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
148.0
nTPM
HPA:
148.0
nTPM
GTEx:
101.8
nTPM
FANTOM5:
178.0
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA008352
Antibody CAB001994
Cholangiocytes
Medium
Low
Hepatocytes
Medium
Not detected
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
148.0
Female, age 60
Liver sample 21 nTPM: 128.1
Male, age 54
Liver sample 23 nTPM: 121
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 123.9
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 172.7
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 179.1
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 158.5
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 157.5
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 152
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 130.5
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 157.1
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
101.8
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 101.8
Samples: 226
Max nTPM: 254.0
Min nTPM: 49.7
Std nTPM: 30.6
Median nTPM: 98.3
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
254.0
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
214.2
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
203.3
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
184.1
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
177.8
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
172.6
GTEX-S32W-1926-SM-4AD63
50-59 years, female
170.7
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
168.1
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
164.3
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
162.4
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
161.7
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
161.0
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
159.5
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
158.2
GTEX-14PJO-1726-SM-68719
60-69 years, male
156.1
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
152.2
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
149.6
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
147.9
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
147.7
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
147.3
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
146.8
GTEX-14XAO-0226-SM-68728
60-69 years, female
143.0
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
142.1
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
140.6
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
140.4
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
138.8
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
138.2
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
138.0
GTEX-QEL4-1226-SM-447A4
50-59 years, male
138.0
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
137.3
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
136.3
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
135.9
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
134.0
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
133.9
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
129.8
GTEX-REY6-1226-SM-48FDR
60-69 years, male
128.5
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
128.2
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
128.1
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
127.9
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
126.4
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
125.9
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
125.2
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
124.9
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
124.8
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
123.2
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
121.4
GTEX-18A66-2026-SM-7189C
60-69 years, male
118.9
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
117.6
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
116.7
GTEX-1B932-1426-SM-793AN
40-49 years, female
116.6
GTEX-Q734-0326-SM-48U15
40-49 years, female
116.6
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
116.4
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
116.1
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
116.1
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
115.7
GTEX-14PHX-0526-SM-664NW
50-59 years, male
114.8
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
114.5
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
114.1
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
113.5
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
113.2
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
112.9
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
112.8
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
112.6
GTEX-S33H-1626-SM-4AD68
30-39 years, male
111.7
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
111.6
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
111.4
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
111.2
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
111.1
GTEX-12696-0826-SM-5EGGE
60-69 years, male
109.8
GTEX-R53T-0326-SM-48FEC
50-59 years, female
109.1
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
108.6
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
108.4
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
107.9
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
107.5
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
107.4
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
107.3
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
107.2
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
106.9
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
106.7
GTEX-P78B-1326-SM-3P611
40-49 years, female
106.6
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
106.4
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
106.3
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
106.2
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
106.2
GTEX-QESD-2026-SM-447BI
20-29 years, male
106.1
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
106.1
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
106.0
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
105.9
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
105.6
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
105.6
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
105.3
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
105.2
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
105.0
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
105.0
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
104.1
GTEX-X261-1726-SM-4PQYT
50-59 years, male
103.9
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
103.2
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
103.1
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
103.0
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
102.9
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
102.8
GTEX-17HHE-0126-SM-79398
50-59 years, male
102.3
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
102.2
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
102.0
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
101.8
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
101.2
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
101.2
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
100.7
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
100.1
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
100.1
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
99.8
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
99.1
GTEX-13113-1326-SM-5GCOI
60-69 years, female
98.4
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
98.1
GTEX-1399T-0826-SM-5IFES
60-69 years, male
97.3
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
96.7
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
96.5
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
96.3
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
96.1
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
96.0
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
95.8
GTEX-O5YV-0726-SM-EV798
60-69 years, female
94.7
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
94.3
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
94.0
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
93.9
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
93.9
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
92.7
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
91.7
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
91.2
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
90.3
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
90.2
GTEX-RU72-1426-SM-46MUF
50-59 years, female
89.9
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
89.6
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
89.2
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
88.9
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
88.8
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
88.0
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
87.7
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
87.4
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
87.4
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
87.4
GTEX-14JG1-1626-SM-664NH
40-49 years, male
87.0
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
86.6
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
86.0
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
85.8
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
85.6
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
85.6
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
85.3
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
85.0
GTEX-14E7W-1526-SM-6871X
70-79 years, male
84.8
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
84.7
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
84.1
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
84.1
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
83.7
GTEX-11GSP-0626-SM-5986T
60-69 years, female
83.6
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
83.6
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
83.6
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
83.5
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
83.1
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
82.8
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
82.4
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
82.4
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
82.2
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
82.1
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
82.0
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
81.8
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
81.6
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
80.8
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
80.4
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
79.8
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
79.4
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
79.2
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
78.9
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
78.8
GTEX-YECK-1926-SM-4W21H
60-69 years, male
78.8
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
78.6
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
77.7
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
77.4
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
77.0
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
76.9
GTEX-18A7A-1526-SM-72D69
50-59 years, female
76.5
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
76.4
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
76.2
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
76.0
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
75.8
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
75.7
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
74.9
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
74.6
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
74.1
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
73.9
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
73.7
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
73.5
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
73.2
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
72.5
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
72.0
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
71.8
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
71.2
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
71.2
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
70.6
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
70.1
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
69.3
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
68.8
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
68.6
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
68.5
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
68.4
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
67.9
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
67.5
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
66.7
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
66.6
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
66.0
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
64.8
GTEX-13112-1426-SM-5EGH8
50-59 years, male
64.6
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
64.3
GTEX-1B933-1226-SM-731DW
50-59 years, female
63.8
GTEX-11ZUS-2526-SM-59872
30-39 years, male
63.4
GTEX-18465-1626-SM-7LG6N
50-59 years, male
63.4
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
63.4
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
62.6
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
62.5
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
62.4
GTEX-17F96-1226-SM-79OK2
70-79 years, male
61.5
GTEX-144GL-1426-SM-79OMA
50-59 years, male
60.7
GTEX-RN64-1826-SM-48FDV
50-59 years, male
56.7
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
53.0
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
51.0
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
49.7
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
