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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:77.8 nTPM
HPA Brain:113.9 nTPM
GTEx:77.8 nTPM
FANTOM5:33.2 Scaled Tags Per Million
Pig:44.4 nTPM
Mouse:178.4 nTPM
Allen mouse:16.4 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

113.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 98.1
2586 Male, age 75, left hemisphere 121.1
2411 Female, age 72, unknown 115.3
1833 Male, age 53, unknown 106.3
1830 Male, age 51, unknown 104.2
1870 Female, age 42, unknown 100.0
2019 Male, age 18, unknown 92.9
2828 Female, age 72, unknown 90.2
2666 Male, age 74, left hemisphere 89.0
1827 Male, age 72, unknown 83.5
2219 Male, age 76, both hemispheres 78.6
Dorsal raphe nucleus
nTPM: 83.2
2750 Male, age 76, both hemispheres 102.1
1828 Male, age 53, unknown 87.6
2016 Female, age 72, unknown 82.3
2047 Male, age 72, unknown 78.9
2298 Female, age 72, unknown 65.1
Inferior colliculus
nTPM: 76.0
2849 Male, age 72, unknown 80.3
1890 Male, age 53, unknown 78.4
1848 Female, age 42, unknown 73.6
2097 Female, age 72, unknown 71.7
Median raphe nucleus
nTPM: 70.3
2220 Male, age 76, midline 70.3
Periaquaductal grey, anterior
nTPM: 76.9
2502 Female, age 75, unknown 87.3
1947 Male, age 18, unknown 78.2
1795 Male, age 51, unknown 65.2
Periaquaductal grey, dorsal
nTPM: 63.8
2464 Female, age 72, unknown 81.1
1831 Male, age 72, unknown 61.1
1840 Male, age 53, unknown 59.9
2850 Male, age 76, both hemispheres 53.1
Periaquaductal grey, lateral
nTPM: 60.4
2053 Male, age 18, unknown 65.3
2272 Male, age 74, both hemispheres 58.3
2140 Male, age 76, both hemispheres 57.7
Pretectal area
nTPM: 74.9
2407 Male, age 75, both hemispheres 94.9
2316 Male, age 76, right hemisphere 85.0
1815 Male, age 53, unknown 83.8
1817 Female, age 42, unknown 83.5
2825 Male, age 18, unknown 82.6
2007 Male, age 72, unknown 80.8
2667 Female, age 75, unknown 75.4
1816 Male, age 51, unknown 62.3
1944 Female, age 72, unknown 61.4
2224 Female, age 72, unknown 60.6
2273 Male, age 74, both hemispheres 53.2
Red nucleus
nTPM: 113.9
1904 Male, age 53, unknown 126.4
2588 Male, age 74, left hemisphere 123.6
2227 Male, age 72, unknown 122.6
1865 Male, age 51, unknown 122.1
2769 Male, age 72, unknown 121.3
2503 Female, age 72, unknown 118.3
2823 Male, age 76, right hemisphere 113.3
1821 Female, age 72, unknown 112.0
1954 Female, age 42, unknown 107.6
2584 Male, age 75, left hemisphere 103.3
2785 Male, age 18, unknown 102.7
2725 Female, age 75, unknown 93.9
Substantia nigra
nTPM: 86.2
1851 Male, age 51, unknown 102.6
2699 Male, age 18, unknown 102.2
2583 Male, age 75, right hemisphere 98.6
1916 Female, age 42, unknown 95.3
2409 Female, age 72, unknown 83.5
1889 Female, age 72, unknown 82.3
2665 Male, age 74, both hemispheres 79.6
2590 Female, age 75, unknown 78.3
1941 Male, age 53, unknown 73.1
2241 Male, age 72, unknown 66.4
Superior colliculus
nTPM: 88.1
1913 Female, age 42, unknown 105.4
1995 Male, age 72, unknown 105.1
2668 Female, age 75, unknown 98.3
1895 Male, age 76, right hemisphere 94.8
2664 Male, age 75, both hemispheres 90.1
1839 Male, age 51, unknown 88.9
2587 Male, age 74, left hemisphere 83.4
1796 Male, age 53, unknown 78.1
2087 Female, age 72, unknown 69.3
2261 Male, age 18, unknown 67.9
Ventral tegmental area
nTPM: 87.5
2410 Female, age 72, unknown 107.6
1915 Female, age 42, unknown 89.4
2223 Female, age 72, unknown 88.0
1942 Male, age 51, unknown 85.3
2021 Male, age 53, unknown 78.3
2218 Male, age 76, both hemispheres 76.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

77.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 77.8
Samples: 139

Max nTPM: 201.8
Min nTPM: 36.6
Std nTPM: 26.9
Median nTPM: 70.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 201.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 183.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 162.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 136.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 135.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 132.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 129.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 127.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 123.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 121.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 118.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 117.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 116.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 111.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 107.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 106.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 106.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 105.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 105.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 102.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 102.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 101.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 100.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 100.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 100.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 99.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 99.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 97.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 95.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 94.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 93.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 92.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 91.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 91.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 90.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 90.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 88.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 88.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 88.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 86.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 85.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 84.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 84.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 84.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 82.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 81.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 80.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 80.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 80.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 79.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 79.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 79.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 79.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 78.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 78.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 77.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 77.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 77.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 76.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 76.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 75.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 73.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 73.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 72.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 72.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 72.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 72.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 71.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 71.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 70.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 69.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 69.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 69.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 69.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 69.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 69.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 69.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 69.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 68.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 68.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 67.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 67.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 67.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 67.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 67.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 66.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 66.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 65.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 65.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 65.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 65.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 65.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 64.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 63.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 63.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 63.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 63.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 62.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 61.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 61.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 60.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 60.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 60.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 59.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 59.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 59.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 58.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 58.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 58.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 57.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 57.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 57.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 56.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 56.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 56.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 55.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 55.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 54.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 54.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 54.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 53.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 53.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 53.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 52.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 52.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 51.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 49.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 48.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 47.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 47.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 46.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 44.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 44.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 42.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 42.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 40.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 40.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 39.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 36.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

33.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 33.2
FF:10158-103A5 76 years, female 33.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

44.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 41.2
Samples: 4

Max nTPM: 48.4
Min nTPM: 30.5
Sample A Female 45.1
Sample B Female 30.5
Sample C Male 40.9
Sample D Male 48.4
Midbrain
nTPM: 44.4
Samples: 4

Max nTPM: 57.3
Min nTPM: 39.4
Sample A Female 57.3
Sample B Female 41.3
Sample C Male 39.5
Sample D Male 39.4
Periaqueductal gray
nTPM: 35.8
Samples: 3

Max nTPM: 37.8
Min nTPM: 34.1
Sample B Female 37.8
Sample C Male 35.4
Sample D Male 34.1
Superior colliculi
nTPM: 41.7
Samples: 4

Max nTPM: 51.7
Min nTPM: 23.8
Sample A Female 46.1
Sample B Female 23.8
Sample C Male 45.0
Sample D Male 51.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

178.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 178.4
Samples: 4

Max nTPM: 192.0
Min nTPM: 164.0
Sample A Male 192.0
Sample B Male 169.7
Sample C Female 164.0
Sample D Female 187.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

16.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 16.4
69080509 Antisense, RP_050324_02_B10, Mouse strain C57BL/6J (56 days, male) 16.4

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