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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:84.3 nTPM
HPA Brain:187.0 nTPM
GTEx:84.3 nTPM
FANTOM5:704.7 Scaled Tags Per Million
Pig:96.5 nTPM
Mouse:93.5 nTPM
Allen mouse:0.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

187.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 147.9
1870 Female, age 42, unknown 216.8
2411 Female, age 72, unknown 213.7
1830 Male, age 51, unknown 201.8
1833 Male, age 53, unknown 175.9
2828 Female, age 72, unknown 131.7
2019 Male, age 18, unknown 129.8
1827 Male, age 72, unknown 120.3
2219 Male, age 76, both hemispheres 108.1
2666 Male, age 74, left hemisphere 104.7
2586 Male, age 75, left hemisphere 75.9
Dorsal raphe nucleus
nTPM: 111.8
2750 Male, age 76, both hemispheres 215.4
2016 Female, age 72, unknown 113.7
1828 Male, age 53, unknown 97.2
2047 Male, age 72, unknown 67.7
2298 Female, age 72, unknown 64.9
Inferior colliculus
nTPM: 105.7
2097 Female, age 72, unknown 115.9
1890 Male, age 53, unknown 108.7
1848 Female, age 42, unknown 107.0
2849 Male, age 72, unknown 91.1
Median raphe nucleus
nTPM: 86.2
2220 Male, age 76, midline 86.2
Periaquaductal grey, anterior
nTPM: 110.4
1947 Male, age 18, unknown 160.6
2502 Female, age 75, unknown 99.0
1795 Male, age 51, unknown 71.6
Periaquaductal grey, dorsal
nTPM: 73.9
2464 Female, age 72, unknown 118.9
1831 Male, age 72, unknown 72.4
1840 Male, age 53, unknown 56.7
2850 Male, age 76, both hemispheres 47.7
Periaquaductal grey, lateral
nTPM: 84.8
2272 Male, age 74, both hemispheres 111.9
2053 Male, age 18, unknown 94.5
2140 Male, age 76, both hemispheres 47.9
Pretectal area
nTPM: 95.5
2316 Male, age 76, right hemisphere 147.0
1815 Male, age 53, unknown 124.4
2273 Male, age 74, both hemispheres 111.7
2825 Male, age 18, unknown 106.2
2407 Male, age 75, both hemispheres 96.4
1817 Female, age 42, unknown 96.3
2007 Male, age 72, unknown 94.8
2224 Female, age 72, unknown 92.7
1944 Female, age 72, unknown 61.8
2667 Female, age 75, unknown 61.8
1816 Male, age 51, unknown 57.0
Red nucleus
nTPM: 187.0
1865 Male, age 51, unknown 250.3
1821 Female, age 72, unknown 228.6
1904 Male, age 53, unknown 221.8
1954 Female, age 42, unknown 199.2
2769 Male, age 72, unknown 198.4
2227 Male, age 72, unknown 194.7
2823 Male, age 76, right hemisphere 192.1
2503 Female, age 72, unknown 191.2
2725 Female, age 75, unknown 162.0
2785 Male, age 18, unknown 152.5
2588 Male, age 74, left hemisphere 143.4
2584 Male, age 75, left hemisphere 110.3
Substantia nigra
nTPM: 110.7
2590 Female, age 75, unknown 160.0
2409 Female, age 72, unknown 136.4
1851 Male, age 51, unknown 132.3
1889 Female, age 72, unknown 123.2
2583 Male, age 75, right hemisphere 116.5
2241 Male, age 72, unknown 112.4
1941 Male, age 53, unknown 92.8
1916 Female, age 42, unknown 90.3
2699 Male, age 18, unknown 83.7
2665 Male, age 74, both hemispheres 59.0
Superior colliculus
nTPM: 133.1
1913 Female, age 42, unknown 213.5
1995 Male, age 72, unknown 186.2
1895 Male, age 76, right hemisphere 174.5
2587 Male, age 74, left hemisphere 166.1
2668 Female, age 75, unknown 143.6
1839 Male, age 51, unknown 134.3
1796 Male, age 53, unknown 101.2
2261 Male, age 18, unknown 95.5
2087 Female, age 72, unknown 67.6
2664 Male, age 75, both hemispheres 48.7
Ventral tegmental area
nTPM: 133.7
2223 Female, age 72, unknown 200.6
2410 Female, age 72, unknown 169.3
1915 Female, age 42, unknown 114.8
1942 Male, age 51, unknown 111.7
2021 Male, age 53, unknown 106.5
2218 Male, age 76, both hemispheres 99.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

84.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 84.3
Samples: 139

Max nTPM: 277.3
Min nTPM: 17.7
Std nTPM: 51.7
Median nTPM: 65.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 277.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 248.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 247.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 245.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 240.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 231.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 224.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 217.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 198.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 193.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 176.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 165.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 152.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 147.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 142.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 141.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 137.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 137.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 133.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 129.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 127.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 127.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 123.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 121.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 120.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 116.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 115.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 113.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 106.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 105.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 105.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 102.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 101.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 100.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 99.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 98.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 97.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 94.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 94.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 90.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 88.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 88.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 87.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 86.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 85.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 83.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 82.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 82.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 82.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 80.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 79.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 79.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 79.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 78.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 78.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 77.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 77.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 76.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 75.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 74.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 71.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 69.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 68.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 68.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 67.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 67.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 67.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 67.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 65.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 65.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 65.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 65.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 64.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 64.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 64.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 64.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 63.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 63.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 63.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 63.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 63.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 62.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 62.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 62.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 61.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 60.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 59.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 59.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 59.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 59.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 59.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 58.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 58.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 57.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 57.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 56.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 55.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 55.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 55.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 54.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 54.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 54.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 53.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 53.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 52.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 51.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 50.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 50.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 49.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 49.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 46.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 46.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 46.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 46.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 45.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 45.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 44.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 44.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 43.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 43.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 43.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 43.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 42.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 42.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 42.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 40.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 39.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 38.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 37.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 35.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 35.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 34.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 33.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 31.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 30.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 29.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 26.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 20.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 17.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

704.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 704.7
FF:10158-103A5 76 years, female 704.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

96.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 96.4
Samples: 4

Max nTPM: 137.4
Min nTPM: 58.7
Sample A Female 99.8
Sample B Female 58.7
Sample C Male 89.8
Sample D Male 137.4
Midbrain
nTPM: 96.5
Samples: 4

Max nTPM: 134.1
Min nTPM: 70.2
Sample A Female 134.1
Sample B Female 99.4
Sample C Male 70.2
Sample D Male 82.2
Periaqueductal gray
nTPM: 80.4
Samples: 3

Max nTPM: 87.7
Min nTPM: 69.4
Sample B Female 84.0
Sample C Male 69.4
Sample D Male 87.7
Superior colliculi
nTPM: 78.3
Samples: 4

Max nTPM: 108.4
Min nTPM: 32.9
Sample A Female 84.7
Sample B Female 32.9
Sample C Male 87.1
Sample D Male 108.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

93.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 93.5
Samples: 4

Max nTPM: 105.4
Min nTPM: 82.7
Sample A Male 82.7
Sample B Male 92.9
Sample C Female 105.4
Sample D Female 93.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.8
76003522 Antisense, RP_060608_02_F03, Mouse strain C57BL/6J (56 days, male) 0.8

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