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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:191.0 nTPM
HPA Brain:509.0 nTPM
GTEx:191.0 nTPM
FANTOM5:197.2 Scaled Tags Per Million
Pig:621.5 nTPM
Mouse:423.3 nTPM
Allen mouse:13.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

509.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 364.2
1827 Male, age 72, unknown 520.3
2828 Female, age 72, unknown 431.4
2666 Male, age 74, left hemisphere 426.1
2019 Male, age 18, unknown 421.8
2411 Female, age 72, unknown 348.6
2219 Male, age 76, both hemispheres 330.4
1870 Female, age 42, unknown 319.9
2586 Male, age 75, left hemisphere 316.0
1833 Male, age 53, unknown 265.8
1830 Male, age 51, unknown 261.6
Dorsal raphe nucleus
nTPM: 345.2
2298 Female, age 72, unknown 498.6
2750 Male, age 76, both hemispheres 361.7
2047 Male, age 72, unknown 340.7
1828 Male, age 53, unknown 296.9
2016 Female, age 72, unknown 228.2
Inferior colliculus
nTPM: 285.4
2097 Female, age 72, unknown 374.7
1890 Male, age 53, unknown 272.5
1848 Female, age 42, unknown 263.3
2849 Male, age 72, unknown 231.1
Median raphe nucleus
nTPM: 411.1
2220 Male, age 76, midline 411.1
Periaquaductal grey, anterior
nTPM: 466.6
1795 Male, age 51, unknown 551.6
1947 Male, age 18, unknown 469.5
2502 Female, age 75, unknown 378.7
Periaquaductal grey, dorsal
nTPM: 314.0
1831 Male, age 72, unknown 375.5
2850 Male, age 76, both hemispheres 312.9
1840 Male, age 53, unknown 300.9
2464 Female, age 72, unknown 266.9
Periaquaductal grey, lateral
nTPM: 323.8
2272 Male, age 74, both hemispheres 354.7
2053 Male, age 18, unknown 343.5
2140 Male, age 76, both hemispheres 273.1
Pretectal area
nTPM: 509.0
1816 Male, age 51, unknown 831.8
1944 Female, age 72, unknown 720.3
1817 Female, age 42, unknown 653.8
2007 Male, age 72, unknown 634.8
1815 Male, age 53, unknown 619.4
2667 Female, age 75, unknown 426.0
2224 Female, age 72, unknown 393.7
2273 Male, age 74, both hemispheres 356.9
2407 Male, age 75, both hemispheres 355.1
2825 Male, age 18, unknown 324.2
2316 Male, age 76, right hemisphere 282.5
Red nucleus
nTPM: 291.2
2785 Male, age 18, unknown 403.1
2725 Female, age 75, unknown 379.5
2584 Male, age 75, left hemisphere 325.7
1821 Female, age 72, unknown 308.9
2588 Male, age 74, left hemisphere 298.5
2503 Female, age 72, unknown 283.2
1865 Male, age 51, unknown 274.1
1954 Female, age 42, unknown 269.4
1904 Male, age 53, unknown 263.7
2823 Male, age 76, right hemisphere 250.8
2769 Male, age 72, unknown 220.9
2227 Male, age 72, unknown 216.8
Substantia nigra
nTPM: 426.0
1916 Female, age 42, unknown 556.8
1889 Female, age 72, unknown 556.3
1941 Male, age 53, unknown 481.1
1851 Male, age 51, unknown 451.7
2241 Male, age 72, unknown 423.6
2409 Female, age 72, unknown 409.5
2590 Female, age 75, unknown 384.4
2583 Male, age 75, right hemisphere 362.3
2665 Male, age 74, both hemispheres 360.2
2699 Male, age 18, unknown 274.0
Superior colliculus
nTPM: 410.5
2087 Female, age 72, unknown 560.6
1796 Male, age 53, unknown 533.2
2261 Male, age 18, unknown 496.9
2668 Female, age 75, unknown 449.1
1913 Female, age 42, unknown 400.1
2587 Male, age 74, left hemisphere 395.0
1995 Male, age 72, unknown 344.3
2664 Male, age 75, both hemispheres 319.1
1895 Male, age 76, right hemisphere 312.6
1839 Male, age 51, unknown 294.4
Ventral tegmental area
nTPM: 375.9
2218 Male, age 76, both hemispheres 416.6
2410 Female, age 72, unknown 408.2
1915 Female, age 42, unknown 393.7
2223 Female, age 72, unknown 387.1
2021 Male, age 53, unknown 328.8
1942 Male, age 51, unknown 321.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

191.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 191.0
Samples: 139

Max nTPM: 458.6
Min nTPM: 117.7
Std nTPM: 60.9
Median nTPM: 175.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 458.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 447.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 426.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 398.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 349.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 345.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 283.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 282.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 282.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 280.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 267.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 257.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 256.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 255.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 251.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 250.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 249.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 246.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 242.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 238.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 234.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 230.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 229.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 229.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 228.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 227.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 224.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 223.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 223.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 222.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 221.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 218.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 217.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 217.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 217.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 214.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 213.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 213.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 211.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 211.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 210.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 210.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 206.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 206.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 205.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 204.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 202.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 201.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 199.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 199.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 196.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 194.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 192.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 191.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 190.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 189.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 189.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 189.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 188.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 187.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 186.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 184.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 184.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 183.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 181.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 181.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 179.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 177.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 177.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 175.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 175.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 175.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 174.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 171.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 171.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 170.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 170.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 169.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 168.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 166.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 166.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 164.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 164.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 164.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 163.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 162.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 160.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 159.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 158.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 158.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 158.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 158.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 157.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 157.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 154.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 154.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 153.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 152.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 151.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 150.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 150.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 149.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 149.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 148.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 148.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 148.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 147.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 146.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 146.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 145.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 145.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 144.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 144.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 144.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 144.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 143.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 142.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 140.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 139.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 138.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 138.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 137.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 137.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 137.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 137.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 136.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 136.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 134.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 134.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 131.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 130.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 130.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 130.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 126.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 123.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 121.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 118.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 118.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 117.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

197.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 197.2
FF:10158-103A5 76 years, female 197.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

621.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 386.1
Samples: 4

Max nTPM: 508.5
Min nTPM: 243.2
Sample A Female 508.5
Sample B Female 354.8
Sample C Male 437.8
Sample D Male 243.2
Midbrain
nTPM: 613.5
Samples: 4

Max nTPM: 1093.4
Min nTPM: 369.7
Sample A Female 465.3
Sample B Female 369.7
Sample C Male 1093.4
Sample D Male 525.4
Periaqueductal gray
nTPM: 357.9
Samples: 3

Max nTPM: 439.9
Min nTPM: 295.8
Sample B Female 338.1
Sample C Male 439.9
Sample D Male 295.8
Superior colliculi
nTPM: 621.5
Samples: 4

Max nTPM: 983.8
Min nTPM: 474.4
Sample A Female 517.9
Sample B Female 474.4
Sample C Male 983.8
Sample D Male 509.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

423.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 423.3
Samples: 4

Max nTPM: 444.2
Min nTPM: 408.0
Sample A Male 408.0
Sample B Male 427.1
Sample C Female 444.2
Sample D Female 413.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

13.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 13.3
1133 Antisense, RP_Baylor_103130, Mouse strain C57BL/6J (56 days, male) 13.3
1134 Antisense, RP_Baylor_103130, Mouse strain C57BL/6J (56 days, male) 9.7

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