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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:72.4 nTPM
HPA Brain:91.8 nTPM
GTEx:72.4 nTPM
FANTOM5:123.4 Scaled Tags Per Million
Pig:161.8 nTPM
Mouse:165.0 nTPM
Allen mouse:4.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

91.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 72.9
2219 Male, age 76, both hemispheres 83.5
1870 Female, age 42, unknown 83.4
1827 Male, age 72, unknown 79.1
1833 Male, age 53, unknown 78.8
1830 Male, age 51, unknown 75.7
2411 Female, age 72, unknown 74.7
2666 Male, age 74, left hemisphere 69.3
2019 Male, age 18, unknown 63.8
2828 Female, age 72, unknown 62.4
2586 Male, age 75, left hemisphere 58.4
Dorsal raphe nucleus
nTPM: 71.1
2750 Male, age 76, both hemispheres 79.7
1828 Male, age 53, unknown 71.3
2016 Female, age 72, unknown 70.9
2047 Male, age 72, unknown 66.9
2298 Female, age 72, unknown 66.9
Inferior colliculus
nTPM: 84.2
2849 Male, age 72, unknown 99.9
2097 Female, age 72, unknown 83.6
1848 Female, age 42, unknown 81.1
1890 Male, age 53, unknown 72.1
Median raphe nucleus
nTPM: 91.8
2220 Male, age 76, midline 91.8
Periaquaductal grey, anterior
nTPM: 75.3
1947 Male, age 18, unknown 80.2
2502 Female, age 75, unknown 76.4
1795 Male, age 51, unknown 69.2
Periaquaductal grey, dorsal
nTPM: 84.4
2850 Male, age 76, both hemispheres 101.6
1840 Male, age 53, unknown 83.5
1831 Male, age 72, unknown 77.7
2464 Female, age 72, unknown 74.7
Periaquaductal grey, lateral
nTPM: 77.5
2140 Male, age 76, both hemispheres 83.8
2272 Male, age 74, both hemispheres 76.5
2053 Male, age 18, unknown 72.2
Pretectal area
nTPM: 78.9
2224 Female, age 72, unknown 82.8
1816 Male, age 51, unknown 82.7
2273 Male, age 74, both hemispheres 82.1
1944 Female, age 72, unknown 81.1
2825 Male, age 18, unknown 80.1
1815 Male, age 53, unknown 79.9
1817 Female, age 42, unknown 79.3
2667 Female, age 75, unknown 77.5
2407 Male, age 75, both hemispheres 74.6
2007 Male, age 72, unknown 74.3
2316 Male, age 76, right hemisphere 73.6
Red nucleus
nTPM: 70.5
2725 Female, age 75, unknown 79.1
1821 Female, age 72, unknown 78.2
2503 Female, age 72, unknown 77.4
1954 Female, age 42, unknown 73.7
2823 Male, age 76, right hemisphere 72.0
2227 Male, age 72, unknown 70.5
1865 Male, age 51, unknown 69.7
2785 Male, age 18, unknown 67.9
2769 Male, age 72, unknown 67.6
1904 Male, age 53, unknown 66.9
2584 Male, age 75, left hemisphere 64.5
2588 Male, age 74, left hemisphere 58.9
Substantia nigra
nTPM: 70.8
1941 Male, age 53, unknown 83.9
2241 Male, age 72, unknown 80.6
2699 Male, age 18, unknown 79.5
1889 Female, age 72, unknown 77.3
2409 Female, age 72, unknown 72.6
1916 Female, age 42, unknown 67.7
1851 Male, age 51, unknown 64.7
2665 Male, age 74, both hemispheres 62.4
2590 Female, age 75, unknown 60.3
2583 Male, age 75, right hemisphere 59.0
Superior colliculus
nTPM: 74.8
1895 Male, age 76, right hemisphere 87.0
2587 Male, age 74, left hemisphere 81.7
1839 Male, age 51, unknown 78.2
2668 Female, age 75, unknown 77.1
2261 Male, age 18, unknown 76.3
1913 Female, age 42, unknown 76.0
1796 Male, age 53, unknown 72.8
2087 Female, age 72, unknown 70.5
2664 Male, age 75, both hemispheres 65.6
1995 Male, age 72, unknown 62.6
Ventral tegmental area
nTPM: 74.5
2223 Female, age 72, unknown 84.6
2218 Male, age 76, both hemispheres 78.3
1942 Male, age 51, unknown 76.6
2021 Male, age 53, unknown 70.2
2410 Female, age 72, unknown 68.9
1915 Female, age 42, unknown 68.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

72.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 72.4
Samples: 139

Max nTPM: 120.6
Min nTPM: 49.7
Std nTPM: 11.3
Median nTPM: 72.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 120.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 119.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 100.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 95.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 94.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 93.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 92.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 90.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 89.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 89.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 88.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 87.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 85.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 85.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 84.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 83.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 83.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 82.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 82.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 81.9
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 81.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 80.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 80.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 80.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 80.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 80.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 79.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 79.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 79.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 78.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 78.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 78.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 78.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 77.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 77.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 77.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 77.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 77.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 77.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 77.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 76.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 76.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 76.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 75.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 75.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 75.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 75.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 75.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 75.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 75.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 75.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 75.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 75.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 74.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 74.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 74.5
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 74.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 74.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 74.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 74.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 73.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 73.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 73.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 73.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 73.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 72.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 72.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 72.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 72.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 72.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 72.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 72.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 71.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 71.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 71.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 71.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 71.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 70.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 70.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 70.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 70.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 69.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 69.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 69.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 68.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 68.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 68.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 68.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 67.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 67.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 67.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 67.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 67.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 66.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 66.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 66.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 66.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 66.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 66.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 65.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 65.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 65.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 64.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 64.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 64.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 64.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 64.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 63.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 63.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 63.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 63.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 63.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 63.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 63.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 63.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 62.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 62.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 62.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 61.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 61.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 61.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 60.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 60.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 60.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 59.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 59.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 59.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 59.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 58.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 57.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 56.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 56.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 55.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 55.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 52.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 51.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 50.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 50.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 49.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

123.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 123.4
FF:10158-103A5 76 years, female 123.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

161.8
Pig sample Sample description nTPM
Substantia nigra
nTPM: 129.9
Samples: 4

Max nTPM: 143.5
Min nTPM: 111.3
Sample A Female 141.0
Sample B Female 111.3
Sample C Male 143.5
Sample D Male 123.8
Midbrain
nTPM: 161.7
Samples: 4

Max nTPM: 178.0
Min nTPM: 131.0
Sample A Female 176.4
Sample B Female 131.0
Sample C Male 178.0
Sample D Male 161.5
Periaqueductal gray
nTPM: 144.2
Samples: 3

Max nTPM: 155.3
Min nTPM: 126.5
Sample B Female 126.5
Sample C Male 150.8
Sample D Male 155.3
Superior colliculi
nTPM: 141.4
Samples: 4

Max nTPM: 157.0
Min nTPM: 103.3
Sample A Female 155.1
Sample B Female 103.3
Sample C Male 150.2
Sample D Male 157.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

165.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 165.0
Samples: 4

Max nTPM: 177.2
Min nTPM: 157.5
Sample A Male 157.5
Sample B Male 166.2
Sample C Female 177.2
Sample D Female 159.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

4.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.4
70565135 Antisense, RP_050623_04_C09, Mouse strain C57BL/6J (56 days, male) 4.4

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