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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
Not detected
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
141.8
nTPM
HPA:
80.2
nTPM
GTEx:
141.8
nTPM
FANTOM5:
77.7
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA028875
Cholangiocytes
Not detected
Hepatocytes
Not detected
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
80.2
Female, age 60
Liver sample 21 nTPM: 45.7
Male, age 54
Liver sample 23 nTPM: 32.3
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 40.9
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 22.5
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 58.8
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 279.5
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 74.9
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 123.1
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 31.1
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 92.9
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
141.8
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 141.8
Samples: 226
Max nTPM: 9330.5
Min nTPM: 6.9
Std nTPM: 666.4
Median nTPM: 50.7
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
9330.5
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
2851.9
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
2418.8
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
1200.9
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
450.9
GTEX-18465-1626-SM-7LG6N
50-59 years, male
396.6
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
387.1
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
372.1
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
360.4
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
349.0
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
324.4
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
287.6
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
278.5
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
272.8
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
264.6
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
262.1
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
255.6
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
205.4
GTEX-144GL-1426-SM-79OMA
50-59 years, male
203.5
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
181.8
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
156.2
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
153.9
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
152.7
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
150.2
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
147.6
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
147.3
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
146.7
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
138.7
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
137.4
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
137.0
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
134.8
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
132.1
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
130.5
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
130.5
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
125.7
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
125.3
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
124.6
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
116.6
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
116.4
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
110.2
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
109.3
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
104.8
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
102.7
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
100.5
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
98.4
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
98.2
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
97.4
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
96.9
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
96.5
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
95.6
GTEX-QEL4-1226-SM-447A4
50-59 years, male
94.4
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
92.7
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
92.3
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
89.4
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
88.9
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
86.7
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
84.3
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
82.9
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
82.8
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
80.6
GTEX-X261-1726-SM-4PQYT
50-59 years, male
80.2
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
79.5
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
77.2
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
76.9
GTEX-1B932-1426-SM-793AN
40-49 years, female
75.6
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
74.9
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
74.9
GTEX-S32W-1926-SM-4AD63
50-59 years, female
74.2
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
71.4
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
70.7
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
70.7
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
70.5
GTEX-18A66-2026-SM-7189C
60-69 years, male
69.8
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
68.1
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
68.0
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
67.9
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
67.3
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
66.5
GTEX-14JG1-1626-SM-664NH
40-49 years, male
65.7
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
65.7
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
65.7
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
65.4
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
65.1
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
65.0
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
63.1
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
61.6
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
61.6
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
61.4
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
61.1
GTEX-RN64-1826-SM-48FDV
50-59 years, male
60.5
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
60.4
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
60.2
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
59.7
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
59.7
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
59.6
GTEX-14E7W-1526-SM-6871X
70-79 years, male
59.6
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
58.1
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
57.0
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
56.5
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
56.1
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
55.6
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
54.8
GTEX-11GSP-0626-SM-5986T
60-69 years, female
54.5
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
54.3
GTEX-17HHE-0126-SM-79398
50-59 years, male
52.9
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
52.6
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
52.6
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
52.2
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
51.7
GTEX-RU72-1426-SM-46MUF
50-59 years, female
51.6
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
51.4
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
50.8
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
50.8
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
50.6
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
50.3
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
49.3
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
49.2
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
49.2
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
49.0
GTEX-12696-0826-SM-5EGGE
60-69 years, male
48.4
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
48.3
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
48.2
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
47.7
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
47.2
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
47.0
GTEX-14PJO-1726-SM-68719
60-69 years, male
46.5
GTEX-18A7A-1526-SM-72D69
50-59 years, female
46.4
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
46.2
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
46.2
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
46.2
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
46.0
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
46.0
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
45.9
GTEX-QESD-2026-SM-447BI
20-29 years, male
45.4
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
44.8
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
44.6
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
44.6
GTEX-14PHX-0526-SM-664NW
50-59 years, male
43.8
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
42.0
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
41.9
GTEX-R53T-0326-SM-48FEC
50-59 years, female
41.1
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
40.4
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
39.9
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
39.7
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
39.5
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
38.6
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
37.3
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
37.2
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
36.9
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
36.7
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
36.0
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
35.4
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
35.3
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
35.1
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
35.0
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
34.6
GTEX-S33H-1626-SM-4AD68
30-39 years, male
34.5
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
34.4
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
34.1
GTEX-17F96-1226-SM-79OK2
70-79 years, male
33.9
GTEX-REY6-1226-SM-48FDR
60-69 years, male
33.9
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
33.4
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
33.3
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
33.2
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
32.0
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
31.9
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
31.4
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
30.9
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
30.3
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
30.0
GTEX-1B933-1226-SM-731DW
50-59 years, female
29.7
GTEX-Q734-0326-SM-48U15
40-49 years, female
29.7
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
29.0
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
29.0
GTEX-13112-1426-SM-5EGH8
50-59 years, male
28.0
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
28.0
GTEX-YECK-1926-SM-4W21H
60-69 years, male
28.0
GTEX-1399T-0826-SM-5IFES
60-69 years, male
27.1
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
26.2
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
26.2
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
26.1
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
25.9
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
25.8
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
24.8
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
24.6
GTEX-14XAO-0226-SM-68728
60-69 years, female
24.6
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
24.1
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
24.0
GTEX-P78B-1326-SM-3P611
40-49 years, female
23.8
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
23.6
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
23.6
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
23.4
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
23.4
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
23.1
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
23.0
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
22.8
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
22.7
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
22.6
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
22.5
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
22.2
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
22.1
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
22.1
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
20.5
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
20.4
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
20.0
GTEX-11ZUS-2526-SM-59872
30-39 years, male
19.4
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
19.3
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
19.0
GTEX-13113-1326-SM-5GCOI
60-69 years, female
17.5
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
17.5
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
16.5
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
16.4
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
16.2
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
15.7
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
14.1
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
12.9
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
12.2
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
11.8
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
10.4
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
10.2
GTEX-O5YV-0726-SM-EV798
60-69 years, female
10.0
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
9.3
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
9.3
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
8.9
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
7.8
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
6.9
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
