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TSC22D4
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  • TSC22D4
TISSUE PRIMARY DATA MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN NASOPHARYNX
ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
ANTIBODIES
AND
VALIDATION
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:846.0 nTPM
HPA Brain:785.1 nTPM
GTEx:846.0 nTPM
FANTOM5:859.0 Scaled Tags Per Million
Pig:191.4 nTPM
Mouse:133.4 nTPM
Allen mouse:3.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

785.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 626.9
2586 Male, age 75, left hemisphere 931.9
2828 Female, age 72, unknown 837.5
1833 Male, age 53, unknown 658.5
1870 Female, age 42, unknown 658.2
1830 Male, age 51, unknown 634.4
2411 Female, age 72, unknown 615.3
2019 Male, age 18, unknown 540.5
1827 Male, age 72, unknown 530.0
2666 Male, age 74, left hemisphere 491.0
2219 Male, age 76, both hemispheres 371.6
Dorsal raphe nucleus
nTPM: 547.2
2750 Male, age 76, both hemispheres 605.1
2016 Female, age 72, unknown 603.4
1828 Male, age 53, unknown 567.1
2047 Male, age 72, unknown 486.3
2298 Female, age 72, unknown 474.1
Inferior colliculus
nTPM: 503.8
1848 Female, age 42, unknown 542.3
2849 Male, age 72, unknown 520.3
1890 Male, age 53, unknown 519.4
2097 Female, age 72, unknown 433.1
Median raphe nucleus
nTPM: 393.2
2220 Male, age 76, midline 393.2
Periaquaductal grey, anterior
nTPM: 485.9
2502 Female, age 75, unknown 507.4
1947 Male, age 18, unknown 481.4
1795 Male, age 51, unknown 468.8
Periaquaductal grey, dorsal
nTPM: 479.8
2464 Female, age 72, unknown 540.1
2850 Male, age 76, both hemispheres 488.0
1831 Male, age 72, unknown 448.8
1840 Male, age 53, unknown 442.3
Periaquaductal grey, lateral
nTPM: 492.6
2053 Male, age 18, unknown 551.6
2140 Male, age 76, both hemispheres 505.2
2272 Male, age 74, both hemispheres 420.9
Pretectal area
nTPM: 484.0
1815 Male, age 53, unknown 554.0
2316 Male, age 76, right hemisphere 553.0
2825 Male, age 18, unknown 548.1
2667 Female, age 75, unknown 537.5
1817 Female, age 42, unknown 522.1
2407 Male, age 75, both hemispheres 497.4
2273 Male, age 74, both hemispheres 436.4
1944 Female, age 72, unknown 435.7
2224 Female, age 72, unknown 429.4
2007 Male, age 72, unknown 418.4
1816 Male, age 51, unknown 392.0
Red nucleus
nTPM: 785.1
2769 Male, age 72, unknown 962.4
2823 Male, age 76, right hemisphere 896.3
2227 Male, age 72, unknown 868.1
1865 Male, age 51, unknown 860.7
1904 Male, age 53, unknown 833.8
1954 Female, age 42, unknown 818.9
2503 Female, age 72, unknown 800.0
1821 Female, age 72, unknown 796.9
2588 Male, age 74, left hemisphere 714.4
2725 Female, age 75, unknown 689.0
2785 Male, age 18, unknown 660.1
2584 Male, age 75, left hemisphere 521.2
Substantia nigra
nTPM: 546.0
2699 Male, age 18, unknown 687.6
2583 Male, age 75, right hemisphere 657.1
1851 Male, age 51, unknown 619.5
1916 Female, age 42, unknown 567.6
2409 Female, age 72, unknown 530.1
2665 Male, age 74, both hemispheres 526.2
2590 Female, age 75, unknown 509.6
1889 Female, age 72, unknown 505.4
2241 Male, age 72, unknown 438.6
1941 Male, age 53, unknown 418.0
Superior colliculus
nTPM: 570.8
1995 Male, age 72, unknown 757.9
1913 Female, age 42, unknown 674.0
2664 Male, age 75, both hemispheres 595.3
2668 Female, age 75, unknown 575.7
1796 Male, age 53, unknown 569.9
1839 Male, age 51, unknown 550.6
1895 Male, age 76, right hemisphere 542.8
2587 Male, age 74, left hemisphere 520.7
2087 Female, age 72, unknown 461.6
2261 Male, age 18, unknown 459.7
Ventral tegmental area
nTPM: 542.9
2223 Female, age 72, unknown 589.6
1915 Female, age 42, unknown 575.4
2410 Female, age 72, unknown 569.2
1942 Male, age 51, unknown 530.1
2021 Male, age 53, unknown 517.1
2218 Male, age 76, both hemispheres 475.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

846.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 846.0
Samples: 139

Max nTPM: 2158.9
Min nTPM: 189.1
Std nTPM: 339.9
Median nTPM: 787.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 2158.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1954.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1578.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1513.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1498.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 1497.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1452.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 1444.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1407.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1398.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1378.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1360.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1345.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1331.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1302.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1300.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1287.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 1249.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1221.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1212.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1165.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 1159.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 1146.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1141.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1140.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1130.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1109.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 1104.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1092.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1092.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1083.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 1079.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1072.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 1052.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 1040.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 1033.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1019.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 1018.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 1018.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1016.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1016.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1015.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1008.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 1002.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1002.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 996.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 985.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 971.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 940.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 930.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 928.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 925.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 919.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 914.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 898.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 896.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 889.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 883.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 883.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 883.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 875.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 869.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 861.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 851.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 841.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 827.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 809.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 805.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 795.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 787.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 779.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 772.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 770.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 764.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 760.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 750.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 742.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 741.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 735.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 724.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 723.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 708.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 704.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 701.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 699.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 698.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 697.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 690.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 680.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 678.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 673.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 672.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 663.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 651.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 647.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 645.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 643.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 640.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 639.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 634.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 630.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 622.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 615.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 615.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 611.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 582.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 576.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 573.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 570.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 566.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 561.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 554.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 546.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 545.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 543.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 538.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 532.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 520.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 513.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 508.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 506.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 498.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 495.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 490.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 487.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 449.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 430.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 424.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 420.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 415.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 404.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 392.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 342.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 334.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 330.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 262.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 262.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 260.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 189.1
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

859.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 859.0
FF:10158-103A5 76 years, female 859.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

191.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 186.7
Samples: 4

Max nTPM: 240.4
Min nTPM: 147.2
Sample A Female 202.2
Sample B Female 147.2
Sample C Male 157.1
Sample D Male 240.4
Midbrain
nTPM: 191.4
Samples: 4

Max nTPM: 333.2
Min nTPM: 119.7
Sample A Female 333.2
Sample B Female 192.7
Sample C Male 119.7
Sample D Male 119.8
Periaqueductal gray
nTPM: 142.9
Samples: 3

Max nTPM: 162.3
Min nTPM: 132.7
Sample B Female 162.3
Sample C Male 132.7
Sample D Male 133.6
Superior colliculi
nTPM: 157.2
Samples: 4

Max nTPM: 202.4
Min nTPM: 102.3
Sample A Female 202.4
Sample B Female 102.3
Sample C Male 148.9
Sample D Male 175.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

133.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 133.4
Samples: 4

Max nTPM: 157.6
Min nTPM: 111.5
Sample A Male 157.6
Sample B Male 116.6
Sample C Female 111.5
Sample D Female 147.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

3.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.1
1465 Antisense, RP_040420_01_D05, Mouse strain C57BL/6J (56 days, male) 6.1
1464 Antisense, RP_040420_01_D05, Mouse strain C57BL/6J (56 days, male) 2.1
74581363 Antisense, RP_060215_03_B02, Mouse strain C57BL/6J (56 days, male) 0.1

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