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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:557.2 nTPM
HPA Brain:364.1 nTPM
GTEx:557.2 nTPM
FANTOM5:396.6 Scaled Tags Per Million
Pig:399.4 nTPM
Mouse:622.4 nTPM
Allen mouse:11.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

364.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 272.3
2586 Male, age 75, left hemisphere 331.3
1827 Male, age 72, unknown 295.0
2219 Male, age 76, both hemispheres 290.9
2828 Female, age 72, unknown 272.3
2666 Male, age 74, left hemisphere 268.1
2411 Female, age 72, unknown 264.9
1833 Male, age 53, unknown 263.6
2019 Male, age 18, unknown 258.7
1870 Female, age 42, unknown 254.0
1830 Male, age 51, unknown 224.0
Dorsal raphe nucleus
nTPM: 308.3
2298 Female, age 72, unknown 350.5
2047 Male, age 72, unknown 338.4
1828 Male, age 53, unknown 314.8
2750 Male, age 76, both hemispheres 284.9
2016 Female, age 72, unknown 252.9
Inferior colliculus
nTPM: 266.7
2097 Female, age 72, unknown 280.4
2849 Male, age 72, unknown 278.5
1890 Male, age 53, unknown 271.3
1848 Female, age 42, unknown 236.4
Median raphe nucleus
nTPM: 356.9
2220 Male, age 76, midline 356.9
Periaquaductal grey, anterior
nTPM: 304.7
1795 Male, age 51, unknown 325.3
1947 Male, age 18, unknown 316.5
2502 Female, age 75, unknown 272.2
Periaquaductal grey, dorsal
nTPM: 270.3
2850 Male, age 76, both hemispheres 326.7
1840 Male, age 53, unknown 272.2
1831 Male, age 72, unknown 259.6
2464 Female, age 72, unknown 222.8
Periaquaductal grey, lateral
nTPM: 264.7
2272 Male, age 74, both hemispheres 275.3
2140 Male, age 76, both hemispheres 259.7
2053 Male, age 18, unknown 259.0
Pretectal area
nTPM: 302.6
1816 Male, age 51, unknown 362.8
1817 Female, age 42, unknown 360.9
1944 Female, age 72, unknown 343.8
2007 Male, age 72, unknown 341.8
2667 Female, age 75, unknown 320.1
1815 Male, age 53, unknown 314.2
2224 Female, age 72, unknown 294.5
2825 Male, age 18, unknown 270.3
2273 Male, age 74, both hemispheres 267.7
2316 Male, age 76, right hemisphere 226.4
2407 Male, age 75, both hemispheres 225.9
Red nucleus
nTPM: 290.8
1821 Female, age 72, unknown 358.8
2725 Female, age 75, unknown 352.3
2503 Female, age 72, unknown 299.6
1954 Female, age 42, unknown 286.6
1904 Male, age 53, unknown 285.0
2769 Male, age 72, unknown 283.6
2227 Male, age 72, unknown 279.7
2785 Male, age 18, unknown 276.0
1865 Male, age 51, unknown 271.6
2588 Male, age 74, left hemisphere 269.2
2584 Male, age 75, left hemisphere 268.3
2823 Male, age 76, right hemisphere 258.6
Substantia nigra
nTPM: 364.1
1916 Female, age 42, unknown 514.7
1851 Male, age 51, unknown 424.8
2699 Male, age 18, unknown 397.1
2665 Male, age 74, both hemispheres 382.3
1889 Female, age 72, unknown 346.4
1941 Male, age 53, unknown 331.1
2409 Female, age 72, unknown 320.9
2241 Male, age 72, unknown 313.9
2583 Male, age 75, right hemisphere 308.1
2590 Female, age 75, unknown 301.6
Superior colliculus
nTPM: 263.5
1796 Male, age 53, unknown 319.5
2261 Male, age 18, unknown 282.2
2087 Female, age 72, unknown 273.8
2587 Male, age 74, left hemisphere 270.3
2668 Female, age 75, unknown 267.1
2664 Male, age 75, both hemispheres 253.5
1839 Male, age 51, unknown 249.2
1895 Male, age 76, right hemisphere 248.8
1913 Female, age 42, unknown 243.9
1995 Male, age 72, unknown 226.6
Ventral tegmental area
nTPM: 336.5
1915 Female, age 42, unknown 400.3
2218 Male, age 76, both hemispheres 373.3
2410 Female, age 72, unknown 370.7
2223 Female, age 72, unknown 304.7
1942 Male, age 51, unknown 293.7
2021 Male, age 53, unknown 276.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

557.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 557.2
Samples: 139

Max nTPM: 1050.9
Min nTPM: 247.1
Std nTPM: 150.1
Median nTPM: 555.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1050.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 932.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 907.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 907.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 880.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 865.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 861.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 840.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 820.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 794.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 741.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 736.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 732.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 731.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 729.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 710.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 706.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 705.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 703.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 703.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 702.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 701.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 700.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 699.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 698.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 691.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 690.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 685.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 677.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 675.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 670.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 664.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 660.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 658.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 657.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 656.5
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 652.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 646.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 626.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 623.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 623.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 618.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 617.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 614.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 611.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 609.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 605.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 604.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 604.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 602.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 602.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 601.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 600.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 599.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 595.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 592.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 590.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 587.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 587.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 575.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 575.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 573.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 571.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 567.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 566.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 566.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 565.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 561.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 556.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 555.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 549.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 548.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 546.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 544.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 539.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 536.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 533.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 528.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 524.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 522.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 521.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 519.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 516.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 514.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 511.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 510.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 509.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 507.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 503.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 500.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 500.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 490.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 490.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 489.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 485.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 483.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 479.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 473.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 470.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 469.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 455.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 450.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 447.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 447.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 446.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 444.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 443.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 441.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 438.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 438.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 437.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 435.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 430.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 428.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 425.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 417.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 416.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 414.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 413.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 408.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 394.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 390.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 388.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 387.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 367.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 360.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 354.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 340.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 331.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 331.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 318.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 314.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 306.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 301.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 289.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 288.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 269.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 263.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 247.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

396.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 396.6
FF:10158-103A5 76 years, female 396.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

399.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 337.0
Samples: 4

Max nTPM: 507.2
Min nTPM: 209.6
Sample A Female 507.2
Sample B Female 251.4
Sample C Male 379.9
Sample D Male 209.6
Midbrain
nTPM: 330.0
Samples: 4

Max nTPM: 385.9
Min nTPM: 292.3
Sample A Female 312.0
Sample B Female 292.3
Sample C Male 385.9
Sample D Male 329.8
Periaqueductal gray
nTPM: 242.1
Samples: 3

Max nTPM: 285.0
Min nTPM: 220.1
Sample B Female 221.2
Sample C Male 285.0
Sample D Male 220.1
Superior colliculi
nTPM: 399.4
Samples: 4

Max nTPM: 517.1
Min nTPM: 320.1
Sample A Female 517.1
Sample B Female 320.1
Sample C Male 436.3
Sample D Male 324.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

622.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 622.4
Samples: 4

Max nTPM: 698.7
Min nTPM: 538.8
Sample A Male 698.7
Sample B Male 588.4
Sample C Female 538.8
Sample D Female 663.8

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

11.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 11.8
69734572 Antisense, RP_050503_01_B10, Mouse strain C57BL/6J (56 days, male) 11.8

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