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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
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Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:384.8 nTPM
HPA Brain:358.9 nTPM
GTEx:384.8 nTPM
FANTOM5:173.0 Scaled Tags Per Million
Pig:467.6 nTPM
Mouse:329.6 nTPM
Allen mouse:0.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

358.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 268.7
2019 Male, age 18, unknown 372.7
2219 Male, age 76, both hemispheres 348.7
2411 Female, age 72, unknown 312.2
1827 Male, age 72, unknown 300.4
2828 Female, age 72, unknown 266.4
1833 Male, age 53, unknown 233.8
2666 Male, age 74, left hemisphere 225.7
2586 Male, age 75, left hemisphere 216.3
1870 Female, age 42, unknown 215.5
1830 Male, age 51, unknown 195.8
Dorsal raphe nucleus
nTPM: 316.2
2298 Female, age 72, unknown 435.4
1828 Male, age 53, unknown 331.8
2047 Male, age 72, unknown 304.4
2750 Male, age 76, both hemispheres 276.9
2016 Female, age 72, unknown 232.5
Inferior colliculus
nTPM: 263.5
2097 Female, age 72, unknown 323.3
1890 Male, age 53, unknown 281.7
1848 Female, age 42, unknown 248.3
2849 Male, age 72, unknown 200.7
Median raphe nucleus
nTPM: 322.4
2220 Male, age 76, midline 322.4
Periaquaductal grey, anterior
nTPM: 277.1
1795 Male, age 51, unknown 304.3
1947 Male, age 18, unknown 273.5
2502 Female, age 75, unknown 253.5
Periaquaductal grey, dorsal
nTPM: 225.9
1831 Male, age 72, unknown 234.2
2464 Female, age 72, unknown 232.3
2850 Male, age 76, both hemispheres 222.2
1840 Male, age 53, unknown 215.0
Periaquaductal grey, lateral
nTPM: 228.2
2272 Male, age 74, both hemispheres 297.9
2140 Male, age 76, both hemispheres 193.9
2053 Male, age 18, unknown 192.7
Pretectal area
nTPM: 329.2
2007 Male, age 72, unknown 431.5
1944 Female, age 72, unknown 431.1
1817 Female, age 42, unknown 431.0
1816 Male, age 51, unknown 419.5
2667 Female, age 75, unknown 360.3
1815 Male, age 53, unknown 335.7
2224 Female, age 72, unknown 313.5
2273 Male, age 74, both hemispheres 300.5
2825 Male, age 18, unknown 205.3
2316 Male, age 76, right hemisphere 203.3
2407 Male, age 75, both hemispheres 189.2
Red nucleus
nTPM: 266.6
1821 Female, age 72, unknown 354.8
2785 Male, age 18, unknown 322.1
2725 Female, age 75, unknown 318.3
2503 Female, age 72, unknown 271.2
1954 Female, age 42, unknown 268.2
2823 Male, age 76, right hemisphere 258.7
2227 Male, age 72, unknown 254.3
2769 Male, age 72, unknown 254.1
1904 Male, age 53, unknown 253.0
1865 Male, age 51, unknown 247.4
2588 Male, age 74, left hemisphere 219.8
2584 Male, age 75, left hemisphere 178.0
Substantia nigra
nTPM: 358.9
1916 Female, age 42, unknown 552.9
1851 Male, age 51, unknown 432.1
1941 Male, age 53, unknown 411.6
1889 Female, age 72, unknown 407.0
2241 Male, age 72, unknown 374.5
2409 Female, age 72, unknown 325.9
2665 Male, age 74, both hemispheres 317.0
2699 Male, age 18, unknown 302.1
2590 Female, age 75, unknown 255.2
2583 Male, age 75, right hemisphere 210.6
Superior colliculus
nTPM: 256.9
2087 Female, age 72, unknown 375.5
2261 Male, age 18, unknown 298.4
1796 Male, age 53, unknown 296.1
2668 Female, age 75, unknown 269.0
1895 Male, age 76, right hemisphere 255.6
2587 Male, age 74, left hemisphere 252.0
1913 Female, age 42, unknown 222.8
1839 Male, age 51, unknown 215.8
1995 Male, age 72, unknown 201.2
2664 Male, age 75, both hemispheres 182.7
Ventral tegmental area
nTPM: 332.7
2410 Female, age 72, unknown 445.3
2218 Male, age 76, both hemispheres 424.0
1915 Female, age 42, unknown 385.4
1942 Male, age 51, unknown 290.9
2021 Male, age 53, unknown 226.3
2223 Female, age 72, unknown 224.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

384.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 384.8
Samples: 139

Max nTPM: 953.6
Min nTPM: 130.5
Std nTPM: 146.3
Median nTPM: 360.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 953.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 786.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 775.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 770.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 730.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 716.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 706.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 662.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 634.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 631.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 591.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 586.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 568.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 565.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 561.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 558.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 556.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 550.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 546.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 539.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 535.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 533.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 523.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 519.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 517.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 510.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 509.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 506.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 505.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 504.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 502.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 493.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 491.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 487.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 459.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 457.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 454.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 449.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 448.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 440.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 438.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 428.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 424.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 418.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 417.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 411.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 408.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 408.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 403.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 403.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 399.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 398.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 397.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 394.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 393.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 388.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 386.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 385.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 383.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 382.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 382.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 380.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 379.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 378.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 377.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 376.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 375.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 372.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 370.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 360.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 360.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 359.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 359.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 352.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 351.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 342.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 342.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 341.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 339.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 337.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 333.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 331.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 329.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 328.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 324.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 322.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 321.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 320.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 319.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 319.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 318.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 317.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 317.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 313.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 307.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 305.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 304.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 303.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 301.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 291.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 277.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 277.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 275.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 272.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 264.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 264.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 263.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 263.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 261.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 260.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 260.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 259.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 258.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 253.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 248.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 246.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 239.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 233.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 232.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 230.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 230.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 226.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 222.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 221.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 218.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 217.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 214.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 214.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 210.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 208.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 207.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 204.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 202.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 202.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 194.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 191.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 175.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 164.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 130.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

173.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 173.0
FF:10158-103A5 76 years, female 173.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

467.6
Pig sample Sample description nTPM
Substantia nigra
nTPM: 323.4
Samples: 4

Max nTPM: 462.5
Min nTPM: 230.2
Sample A Female 462.5
Sample B Female 250.3
Sample C Male 350.4
Sample D Male 230.2
Midbrain
nTPM: 389.5
Samples: 4

Max nTPM: 527.7
Min nTPM: 301.1
Sample A Female 391.1
Sample B Female 301.1
Sample C Male 527.7
Sample D Male 338.2
Periaqueductal gray
nTPM: 263.9
Samples: 3

Max nTPM: 310.3
Min nTPM: 223.4
Sample B Female 258.1
Sample C Male 310.3
Sample D Male 223.4
Superior colliculi
nTPM: 467.6
Samples: 4

Max nTPM: 645.8
Min nTPM: 362.7
Sample A Female 491.4
Sample B Female 370.4
Sample C Male 645.8
Sample D Male 362.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

329.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 329.6
Samples: 4

Max nTPM: 348.1
Min nTPM: 308.3
Sample A Male 348.1
Sample B Male 323.8
Sample C Female 308.3
Sample D Female 338.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.4
75233570 Antisense, RP_051121_03_C01, Mouse strain C57BL/6J (56 days, male) 0.4

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