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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:95.9 nTPM
HPA Brain:93.1 nTPM
GTEx:95.9 nTPM
FANTOM5:31.9 Scaled Tags Per Million
Pig:36.0 nTPM
Mouse:128.7 nTPM
Allen mouse:0.1 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

93.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 64.4
2586 Male, age 75, left hemisphere 111.7
2219 Male, age 76, both hemispheres 94.5
2828 Female, age 72, unknown 81.7
1827 Male, age 72, unknown 63.1
2666 Male, age 74, left hemisphere 56.7
1870 Female, age 42, unknown 56.3
2411 Female, age 72, unknown 54.7
1833 Male, age 53, unknown 52.5
1830 Male, age 51, unknown 45.5
2019 Male, age 18, unknown 26.7
Dorsal raphe nucleus
nTPM: 79.6
2047 Male, age 72, unknown 96.5
2298 Female, age 72, unknown 89.8
2016 Female, age 72, unknown 83.0
1828 Male, age 53, unknown 72.1
2750 Male, age 76, both hemispheres 56.6
Inferior colliculus
nTPM: 62.1
2849 Male, age 72, unknown 70.5
1890 Male, age 53, unknown 66.3
1848 Female, age 42, unknown 58.8
2097 Female, age 72, unknown 52.9
Median raphe nucleus
nTPM: 44.6
2220 Male, age 76, midline 44.6
Periaquaductal grey, anterior
nTPM: 73.1
1795 Male, age 51, unknown 81.2
1947 Male, age 18, unknown 76.9
2502 Female, age 75, unknown 61.3
Periaquaductal grey, dorsal
nTPM: 70.8
1840 Male, age 53, unknown 106.1
2464 Female, age 72, unknown 68.6
2850 Male, age 76, both hemispheres 63.9
1831 Male, age 72, unknown 44.7
Periaquaductal grey, lateral
nTPM: 64.1
2140 Male, age 76, both hemispheres 75.7
2053 Male, age 18, unknown 71.5
2272 Male, age 74, both hemispheres 45.2
Pretectal area
nTPM: 54.4
2224 Female, age 72, unknown 82.9
2825 Male, age 18, unknown 75.0
2667 Female, age 75, unknown 59.8
1816 Male, age 51, unknown 58.5
1944 Female, age 72, unknown 57.1
1817 Female, age 42, unknown 53.0
2316 Male, age 76, right hemisphere 50.1
1815 Male, age 53, unknown 49.0
2273 Male, age 74, both hemispheres 42.4
2007 Male, age 72, unknown 36.7
2407 Male, age 75, both hemispheres 34.0
Red nucleus
nTPM: 54.4
2503 Female, age 72, unknown 73.6
2227 Male, age 72, unknown 65.3
2769 Male, age 72, unknown 64.8
2725 Female, age 75, unknown 59.9
1821 Female, age 72, unknown 58.2
2823 Male, age 76, right hemisphere 57.0
1954 Female, age 42, unknown 54.1
1904 Male, age 53, unknown 50.4
2584 Male, age 75, left hemisphere 47.8
2588 Male, age 74, left hemisphere 47.8
1865 Male, age 51, unknown 44.5
2785 Male, age 18, unknown 29.6
Substantia nigra
nTPM: 93.1
2699 Male, age 18, unknown 167.9
1916 Female, age 42, unknown 139.1
1851 Male, age 51, unknown 95.9
2665 Male, age 74, both hemispheres 90.6
2241 Male, age 72, unknown 84.3
2409 Female, age 72, unknown 80.0
2590 Female, age 75, unknown 79.5
2583 Male, age 75, right hemisphere 72.1
1889 Female, age 72, unknown 63.7
1941 Male, age 53, unknown 58.2
Superior colliculus
nTPM: 52.6
1796 Male, age 53, unknown 73.4
2261 Male, age 18, unknown 62.5
2087 Female, age 72, unknown 59.9
2664 Male, age 75, both hemispheres 56.9
2668 Female, age 75, unknown 53.0
1995 Male, age 72, unknown 52.7
1839 Male, age 51, unknown 51.5
1913 Female, age 42, unknown 40.8
1895 Male, age 76, right hemisphere 38.1
2587 Male, age 74, left hemisphere 36.9
Ventral tegmental area
nTPM: 70.2
1915 Female, age 42, unknown 96.1
1942 Male, age 51, unknown 79.8
2410 Female, age 72, unknown 69.5
2218 Male, age 76, both hemispheres 68.8
2021 Male, age 53, unknown 60.8
2223 Female, age 72, unknown 46.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

95.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 95.9
Samples: 139

Max nTPM: 284.9
Min nTPM: 7.2
Std nTPM: 56.1
Median nTPM: 86.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 284.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 271.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 248.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 238.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 233.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 213.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 207.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 203.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 196.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 186.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 181.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 178.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 177.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 176.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 170.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 163.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 163.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 162.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 159.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 157.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 156.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 155.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 154.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 151.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 145.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 141.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 140.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 136.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 136.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 134.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 133.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 131.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 130.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 129.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 123.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 122.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 121.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 121.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 121.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 118.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 117.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 111.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 110.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 109.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 109.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 109.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 108.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 107.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 106.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 106.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 105.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 104.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 103.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 100.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 99.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 99.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 99.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 97.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 96.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 95.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 93.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 92.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 89.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 89.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 89.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 89.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 88.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 88.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 88.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 86.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 85.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 85.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 83.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 83.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 83.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 83.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 82.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 82.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 80.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 79.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 78.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 77.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 76.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 76.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 76.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 75.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 75.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 75.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 74.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 73.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 70.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 67.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 67.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 66.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 65.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 65.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 65.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 64.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 60.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 57.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 57.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 56.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 56.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 56.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 55.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 54.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 54.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 53.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 50.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 49.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 47.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 46.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 46.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 43.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 43.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 42.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 42.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 41.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 39.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 39.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 38.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 36.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 32.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 31.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 30.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 27.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 25.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 25.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 24.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 23.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 23.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 20.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 19.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 16.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 15.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 14.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 12.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 12.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 7.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

31.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 31.9
FF:10158-103A5 76 years, female 31.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

36.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 36.0
Samples: 4

Max nTPM: 46.6
Min nTPM: 25.3
Sample A Female 46.6
Sample B Female 25.3
Sample C Male 31.0
Sample D Male 41.0
Midbrain
nTPM: 34.3
Samples: 4

Max nTPM: 42.2
Min nTPM: 24.8
Sample A Female 42.2
Sample B Female 41.8
Sample C Male 28.3
Sample D Male 24.8
Periaqueductal gray
nTPM: 29.6
Samples: 3

Max nTPM: 35.6
Min nTPM: 25.1
Sample B Female 35.6
Sample C Male 28.0
Sample D Male 25.1
Superior colliculi
nTPM: 29.4
Samples: 4

Max nTPM: 43.0
Min nTPM: 15.6
Sample A Female 43.0
Sample B Female 15.6
Sample C Male 29.3
Sample D Male 29.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

128.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 128.7
Samples: 4

Max nTPM: 146.9
Min nTPM: 114.0
Sample A Male 146.9
Sample B Male 114.0
Sample C Female 120.8
Sample D Female 132.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.1
81600566 Antisense, RP_080625_04_G09, Mouse strain C57BL/6J (56 days, male) 0.3
100145352 Antisense, RP_110519_02_H04, Mouse strain C57BL/6J (56 days, male) 0.0

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