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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
Not detected
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
71.8
nTPM
HPA:
36.7
nTPM
GTEx:
71.8
nTPM
FANTOM5:
110.8
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA026430
Antibody CAB003834
Antibody CAB080093
Cholangiocytes
Not detected
Low
Medium
Hepatocytes
Not detected
Not detected
High
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
36.7
Female, age 60
Liver sample 21 nTPM: 34.7
Male, age 54
Liver sample 23 nTPM: 59
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 41
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 32.3
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 27.7
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 23.5
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 41.4
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 35.3
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 32.7
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 39.7
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
71.8
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 71.8
Samples: 226
Max nTPM: 183.6
Min nTPM: 19.8
Std nTPM: 32.5
Median nTPM: 64.9
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
183.6
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
182.9
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
174.3
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
172.2
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
169.4
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
150.2
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
146.9
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
142.8
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
139.7
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
135.9
GTEX-14E7W-1526-SM-6871X
70-79 years, male
134.3
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
134.1
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
133.4
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
132.8
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
131.6
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
131.2
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
129.8
GTEX-17F96-1226-SM-79OK2
70-79 years, male
128.5
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
127.1
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
127.0
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
125.5
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
121.5
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
120.7
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
118.6
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
118.0
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
117.3
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
117.2
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
115.0
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
113.7
GTEX-11ZUS-2526-SM-59872
30-39 years, male
112.6
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
111.0
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
109.1
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
106.3
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
105.4
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
103.5
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
103.2
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
100.9
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
99.7
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
99.3
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
99.2
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
97.7
GTEX-144GL-1426-SM-79OMA
50-59 years, male
97.1
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
95.9
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
94.9
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
93.1
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
91.9
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
91.9
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
91.8
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
91.7
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
91.5
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
91.2
GTEX-13112-1426-SM-5EGH8
50-59 years, male
91.0
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
90.6
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
90.0
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
89.8
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
88.7
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
88.3
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
88.3
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
87.4
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
87.2
GTEX-RN64-1826-SM-48FDV
50-59 years, male
86.5
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
85.7
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
85.7
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
85.6
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
84.9
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
84.2
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
84.2
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
83.2
GTEX-18465-1626-SM-7LG6N
50-59 years, male
82.8
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
82.7
GTEX-18A7A-1526-SM-72D69
50-59 years, female
82.2
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
82.1
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
81.1
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
81.1
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
80.6
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
79.7
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
79.4
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
79.3
GTEX-R53T-0326-SM-48FEC
50-59 years, female
77.9
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
77.7
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
77.5
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
77.3
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
77.2
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
76.4
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
76.0
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
74.9
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
74.0
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
73.9
GTEX-17HHE-0126-SM-79398
50-59 years, male
72.8
GTEX-1399T-0826-SM-5IFES
60-69 years, male
72.4
GTEX-14PHX-0526-SM-664NW
50-59 years, male
71.9
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
71.8
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
71.5
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
70.7
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
70.7
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
70.0
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
69.6
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
69.5
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
69.0
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
68.3
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
67.8
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
67.5
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
67.4
GTEX-P78B-1326-SM-3P611
40-49 years, female
67.1
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
67.1
GTEX-YECK-1926-SM-4W21H
60-69 years, male
67.0
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
66.4
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
66.4
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
66.2
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
65.7
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
65.4
GTEX-X261-1726-SM-4PQYT
50-59 years, male
65.3
GTEX-REY6-1226-SM-48FDR
60-69 years, male
65.0
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
64.9
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
64.2
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
64.0
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
63.7
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
63.6
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
63.3
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
63.1
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
62.8
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
62.8
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
62.7
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
62.6
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
62.2
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
62.2
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
61.8
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
59.5
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
59.4
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
59.0
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
58.7
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
58.3
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
57.3
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
56.9
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
56.5
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
56.0
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
56.0
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
55.6
GTEX-14JG1-1626-SM-664NH
40-49 years, male
55.3
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
55.3
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
54.9
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
54.6
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
53.9
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
53.8
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
53.2
GTEX-11GSP-0626-SM-5986T
60-69 years, female
53.0
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
52.9
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
52.8
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
52.8
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
52.3
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
52.1
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
52.1
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
52.0
GTEX-14XAO-0226-SM-68728
60-69 years, female
51.9
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
51.1
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
51.1
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
51.1
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
50.9
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
50.7
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
50.4
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
50.3
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
50.3
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
49.8
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
49.4
GTEX-RU72-1426-SM-46MUF
50-59 years, female
49.1
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
49.1
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
48.9
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
48.6
GTEX-14PJO-1726-SM-68719
60-69 years, male
47.9
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
47.4
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
47.3
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
47.0
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
47.0
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
46.6
GTEX-O5YV-0726-SM-EV798
60-69 years, female
46.6
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
46.2
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
46.1
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
45.2
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
44.6
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
44.2
GTEX-13113-1326-SM-5GCOI
60-69 years, female
44.1
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
43.0
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
42.7
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
42.6
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
42.4
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
42.2
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
41.7
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
41.5
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
41.1
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
40.7
GTEX-1B932-1426-SM-793AN
40-49 years, female
40.6
GTEX-1B933-1226-SM-731DW
50-59 years, female
40.5
GTEX-S33H-1626-SM-4AD68
30-39 years, male
39.6
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
39.5
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
39.2
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
39.1
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
38.9
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
38.8
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
38.5
GTEX-S32W-1926-SM-4AD63
50-59 years, female
37.8
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
37.7
GTEX-QEL4-1226-SM-447A4
50-59 years, male
37.4
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
37.3
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
37.0
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
36.5
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
36.2
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
35.9
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
35.9
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
35.6
GTEX-QESD-2026-SM-447BI
20-29 years, male
35.6
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
35.4
GTEX-12696-0826-SM-5EGGE
60-69 years, male
35.2
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
35.1
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
34.9
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
33.8
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
33.5
GTEX-Q734-0326-SM-48U15
40-49 years, female
32.5
GTEX-18A66-2026-SM-7189C
60-69 years, male
32.2
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
31.7
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
31.0
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
30.9
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
30.3
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
29.0
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
28.5
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
27.1
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
19.8
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
