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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:838.0 nTPM
HPA Brain:411.7 nTPM
GTEx:838.0 nTPM
FANTOM5:326.5 Scaled Tags Per Million
Pig:857.9 nTPM
Mouse:223.6 nTPM
Allen mouse:15.5 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

411.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 364.6
2828 Female, age 72, unknown 410.7
2411 Female, age 72, unknown 390.1
1870 Female, age 42, unknown 389.5
1827 Male, age 72, unknown 384.1
1833 Male, age 53, unknown 375.0
1830 Male, age 51, unknown 364.5
2666 Male, age 74, left hemisphere 364.3
2019 Male, age 18, unknown 354.7
2586 Male, age 75, left hemisphere 334.0
2219 Male, age 76, both hemispheres 279.0
Dorsal raphe nucleus
nTPM: 399.4
2298 Female, age 72, unknown 463.2
2750 Male, age 76, both hemispheres 398.4
1828 Male, age 53, unknown 389.1
2016 Female, age 72, unknown 380.5
2047 Male, age 72, unknown 365.8
Inferior colliculus
nTPM: 349.2
2097 Female, age 72, unknown 397.8
1890 Male, age 53, unknown 339.7
2849 Male, age 72, unknown 334.1
1848 Female, age 42, unknown 325.2
Median raphe nucleus
nTPM: 411.7
2220 Male, age 76, midline 411.7
Periaquaductal grey, anterior
nTPM: 352.5
1947 Male, age 18, unknown 369.5
1795 Male, age 51, unknown 348.9
2502 Female, age 75, unknown 339.2
Periaquaductal grey, dorsal
nTPM: 348.7
2850 Male, age 76, both hemispheres 380.8
1840 Male, age 53, unknown 360.1
1831 Male, age 72, unknown 343.9
2464 Female, age 72, unknown 310.0
Periaquaductal grey, lateral
nTPM: 353.1
2053 Male, age 18, unknown 357.6
2140 Male, age 76, both hemispheres 355.5
2272 Male, age 74, both hemispheres 346.3
Pretectal area
nTPM: 376.2
1817 Female, age 42, unknown 414.3
2667 Female, age 75, unknown 404.3
1815 Male, age 53, unknown 396.2
2273 Male, age 74, both hemispheres 389.0
1816 Male, age 51, unknown 386.5
2224 Female, age 72, unknown 384.8
2007 Male, age 72, unknown 373.1
2825 Male, age 18, unknown 366.9
1944 Female, age 72, unknown 362.6
2316 Male, age 76, right hemisphere 343.5
2407 Male, age 75, both hemispheres 316.4
Red nucleus
nTPM: 372.5
1821 Female, age 72, unknown 471.2
2503 Female, age 72, unknown 402.6
2823 Male, age 76, right hemisphere 400.3
1904 Male, age 53, unknown 393.9
1865 Male, age 51, unknown 381.5
2227 Male, age 72, unknown 376.4
1954 Female, age 42, unknown 372.4
2769 Male, age 72, unknown 370.5
2725 Female, age 75, unknown 357.8
2785 Male, age 18, unknown 356.5
2588 Male, age 74, left hemisphere 310.4
2584 Male, age 75, left hemisphere 276.7
Substantia nigra
nTPM: 395.0
1916 Female, age 42, unknown 481.6
1851 Male, age 51, unknown 426.4
2699 Male, age 18, unknown 423.0
2241 Male, age 72, unknown 411.7
1889 Female, age 72, unknown 401.2
2665 Male, age 74, both hemispheres 400.1
1941 Male, age 53, unknown 366.2
2409 Female, age 72, unknown 364.5
2590 Female, age 75, unknown 350.8
2583 Male, age 75, right hemisphere 324.7
Superior colliculus
nTPM: 368.2
2587 Male, age 74, left hemisphere 409.9
2668 Female, age 75, unknown 409.3
1913 Female, age 42, unknown 396.3
1995 Male, age 72, unknown 373.4
1796 Male, age 53, unknown 367.0
2087 Female, age 72, unknown 359.6
2261 Male, age 18, unknown 347.9
2664 Male, age 75, both hemispheres 347.5
1839 Male, age 51, unknown 339.3
1895 Male, age 76, right hemisphere 331.6
Ventral tegmental area
nTPM: 398.1
1915 Female, age 42, unknown 443.9
2410 Female, age 72, unknown 430.4
2218 Male, age 76, both hemispheres 394.0
2223 Female, age 72, unknown 375.4
1942 Male, age 51, unknown 374.0
2021 Male, age 53, unknown 370.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

838.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 838.0
Samples: 139

Max nTPM: 1594.4
Min nTPM: 518.6
Std nTPM: 174.2
Median nTPM: 818.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1594.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1428.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1341.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1274.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1266.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 1168.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1145.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1125.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1113.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1108.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1077.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 1067.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1059.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 1050.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1045.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1042.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1037.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1029.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1009.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1002.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 989.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 975.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 974.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 972.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 966.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 963.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 956.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 945.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 945.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 945.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 944.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 944.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 941.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 940.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 935.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 932.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 925.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 919.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 918.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 908.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 901.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 899.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 893.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 893.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 893.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 890.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 885.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 880.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 878.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 877.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 877.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 876.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 869.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 866.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 862.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 862.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 859.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 852.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 847.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 845.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 845.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 844.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 843.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 839.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 839.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 827.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 822.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 822.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 820.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 818.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 816.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 815.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 807.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 805.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 805.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 803.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 802.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 785.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 779.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 776.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 776.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 776.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 775.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 769.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 768.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 767.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 759.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 753.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 753.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 753.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 752.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 743.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 739.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 738.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 734.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 732.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 731.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 725.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 724.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 723.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 721.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 720.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 716.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 715.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 710.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 708.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 707.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 703.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 702.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 701.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 699.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 698.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 696.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 696.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 695.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 692.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 692.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 689.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 683.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 677.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 667.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 666.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 660.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 655.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 652.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 642.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 642.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 638.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 637.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 633.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 628.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 624.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 597.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 593.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 573.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 566.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 564.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 527.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 518.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

326.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 326.5
FF:10158-103A5 76 years, female 326.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

857.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 809.0
Samples: 4

Max nTPM: 1048.5
Min nTPM: 691.9
Sample A Female 1048.5
Sample B Female 722.5
Sample C Male 691.9
Sample D Male 773.2
Midbrain
nTPM: 858.0
Samples: 4

Max nTPM: 1438.0
Min nTPM: 576.8
Sample A Female 1438.0
Sample B Female 810.4
Sample C Male 606.6
Sample D Male 576.8
Periaqueductal gray
nTPM: 646.5
Samples: 3

Max nTPM: 676.6
Min nTPM: 620.6
Sample B Female 620.6
Sample C Male 676.6
Sample D Male 642.4
Superior colliculi
nTPM: 765.7
Samples: 4

Max nTPM: 993.6
Min nTPM: 631.8
Sample A Female 993.6
Sample B Female 631.8
Sample C Male 718.4
Sample D Male 719.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

223.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 223.6
Samples: 4

Max nTPM: 242.5
Min nTPM: 211.5
Sample A Male 242.5
Sample B Male 219.4
Sample C Female 211.5
Sample D Female 221.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

15.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 15.5
2245 Antisense, RP_040420_01_B03, Mouse strain C57BL/6J (56 days, male) 15.5
2246 Antisense, RP_040420_01_B03, Mouse strain C57BL/6J (56 days, male) 15.2

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