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TISSUE PRIMARY DATA MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM
ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN NASOPHARYNX
ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE
SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
ANTIBODIES
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VALIDATION
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:12.0 nTPM
HPA Brain:59.5 nTPM
GTEx:12.0 nTPM
FANTOM5:26.5 Scaled Tags Per Million
Pig:48.3 nTPM
Mouse:56.3 nTPM
Allen mouse:3.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

59.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 43.6
2586 Male, age 75, left hemisphere 51.0
2019 Male, age 18, unknown 50.8
1827 Male, age 72, unknown 48.7
1870 Female, age 42, unknown 46.2
2411 Female, age 72, unknown 44.3
2666 Male, age 74, left hemisphere 42.7
2828 Female, age 72, unknown 41.3
1833 Male, age 53, unknown 38.3
2219 Male, age 76, both hemispheres 37.2
1830 Male, age 51, unknown 36.1
Dorsal raphe nucleus
nTPM: 51.5
2298 Female, age 72, unknown 60.6
1828 Male, age 53, unknown 53.4
2016 Female, age 72, unknown 53.2
2047 Male, age 72, unknown 49.7
2750 Male, age 76, both hemispheres 40.8
Inferior colliculus
nTPM: 55.5
2097 Female, age 72, unknown 67.1
1890 Male, age 53, unknown 59.8
1848 Female, age 42, unknown 50.3
2849 Male, age 72, unknown 44.9
Median raphe nucleus
nTPM: 39.6
2220 Male, age 76, midline 39.6
Periaquaductal grey, anterior
nTPM: 59.5
1795 Male, age 51, unknown 66.6
1947 Male, age 18, unknown 62.5
2502 Female, age 75, unknown 49.3
Periaquaductal grey, dorsal
nTPM: 54.1
1840 Male, age 53, unknown 63.2
2850 Male, age 76, both hemispheres 58.8
2464 Female, age 72, unknown 48.3
1831 Male, age 72, unknown 46.2
Periaquaductal grey, lateral
nTPM: 57.8
2272 Male, age 74, both hemispheres 59.5
2053 Male, age 18, unknown 58.5
2140 Male, age 76, both hemispheres 55.3
Pretectal area
nTPM: 58.5
1816 Male, age 51, unknown 70.0
2273 Male, age 74, both hemispheres 68.2
1817 Female, age 42, unknown 66.5
1944 Female, age 72, unknown 65.1
2007 Male, age 72, unknown 63.9
2667 Female, age 75, unknown 57.9
2825 Male, age 18, unknown 56.9
2224 Female, age 72, unknown 56.3
1815 Male, age 53, unknown 53.8
2407 Male, age 75, both hemispheres 44.4
2316 Male, age 76, right hemisphere 40.4
Red nucleus
nTPM: 47.7
1954 Female, age 42, unknown 59.7
1821 Female, age 72, unknown 58.7
1904 Male, age 53, unknown 49.4
2785 Male, age 18, unknown 48.4
1865 Male, age 51, unknown 48.2
2503 Female, age 72, unknown 47.4
2227 Male, age 72, unknown 46.7
2769 Male, age 72, unknown 46.3
2725 Female, age 75, unknown 45.2
2823 Male, age 76, right hemisphere 44.5
2588 Male, age 74, left hemisphere 39.5
2584 Male, age 75, left hemisphere 38.4
Substantia nigra
nTPM: 38.3
1889 Female, age 72, unknown 52.7
2590 Female, age 75, unknown 46.1
2583 Male, age 75, right hemisphere 42.9
2241 Male, age 72, unknown 40.9
2665 Male, age 74, both hemispheres 39.8
1916 Female, age 42, unknown 34.7
2409 Female, age 72, unknown 34.4
1851 Male, age 51, unknown 33.9
1941 Male, age 53, unknown 33.0
2699 Male, age 18, unknown 24.2
Superior colliculus
nTPM: 50.3
2261 Male, age 18, unknown 60.6
2087 Female, age 72, unknown 60.1
1995 Male, age 72, unknown 55.8
2668 Female, age 75, unknown 50.8
1796 Male, age 53, unknown 50.4
1913 Female, age 42, unknown 49.4
2587 Male, age 74, left hemisphere 47.1
2664 Male, age 75, both hemispheres 45.3
1839 Male, age 51, unknown 45.2
1895 Male, age 76, right hemisphere 38.5
Ventral tegmental area
nTPM: 40.0
2410 Female, age 72, unknown 46.9
2223 Female, age 72, unknown 41.9
1942 Male, age 51, unknown 41.7
2021 Male, age 53, unknown 38.8
2218 Male, age 76, both hemispheres 36.6
1915 Female, age 42, unknown 34.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

12.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 12.0
Samples: 139

Max nTPM: 30.8
Min nTPM: 6.0
Std nTPM: 3.8
Median nTPM: 11.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 30.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 29.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 25.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 23.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 20.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 18.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 18.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 18.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 17.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 16.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 16.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 16.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 16.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 16.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 16.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 15.8
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 15.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 15.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 15.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 15.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 14.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 14.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 14.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 14.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 14.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 14.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 14.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 14.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 14.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 14.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 14.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 13.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 13.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 13.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 13.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 13.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 13.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 13.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 13.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 13.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 13.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 13.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 13.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 13.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 13.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 13.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 12.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 12.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 12.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 12.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 12.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 12.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 12.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 12.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 12.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 12.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 12.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 12.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 12.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 12.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 11.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 11.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 11.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 11.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 11.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 11.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 11.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 11.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 11.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 11.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 11.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 11.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 11.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 10.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 10.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 10.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 10.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 10.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 10.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 10.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 10.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 10.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 10.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 10.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 10.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 10.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 10.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 10.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 10.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 10.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 10.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 10.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 10.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 10.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 10.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 10.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 9.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 9.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 9.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 9.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 9.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 9.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 9.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 9.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 9.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 9.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 9.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 9.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 9.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 9.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 9.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 9.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 9.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 9.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 9.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 9.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 9.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 8.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 8.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 8.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 8.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 8.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 8.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 8.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 8.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 8.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 8.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 8.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 8.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 8.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 8.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 8.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 7.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 7.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 7.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 6.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 6.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 6.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 6.0
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

26.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 26.5
FF:10158-103A5 76 years, female 26.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

48.3
Pig sample Sample description nTPM
Substantia nigra
nTPM: 27.9
Samples: 4

Max nTPM: 33.1
Min nTPM: 22.2
Sample A Female 31.2
Sample B Female 22.2
Sample C Male 33.1
Sample D Male 25.2
Midbrain
nTPM: 48.3
Samples: 4

Max nTPM: 69.5
Min nTPM: 30.3
Sample A Female 30.3
Sample B Female 33.3
Sample C Male 69.5
Sample D Male 60.1
Periaqueductal gray
nTPM: 44.0
Samples: 3

Max nTPM: 50.0
Min nTPM: 40.9
Sample B Female 41.2
Sample C Male 50.0
Sample D Male 40.9
Superior colliculi
nTPM: 44.1
Samples: 4

Max nTPM: 56.4
Min nTPM: 27.5
Sample A Female 45.2
Sample B Female 27.5
Sample C Male 56.4
Sample D Male 47.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

56.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 56.3
Samples: 4

Max nTPM: 62.5
Min nTPM: 50.7
Sample A Male 50.7
Sample B Male 55.0
Sample C Female 62.5
Sample D Female 57.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

3.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.9
79632275 Antisense, RP_071204_01_B10, Mouse strain C57BL/6J (56 days, male) 6.1
79556666 Antisense, RP_071204_01_B10, Mouse strain C57BL/6J (56 days, male) 4.9
237 Antisense, RP_Baylor_102676, Mouse strain C57BL/6J (56 days, male) 1.7
236 Antisense, RP_Baylor_102676, Mouse strain C57BL/6J (56 days, male) 0.3

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The Human Protein Atlas

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.


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